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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=37088
Proper Citation: RRID:MMRRC_037088-UNC
Description: Mus musculus with name B6.129S6(C)-Fli1tm1.1Dkw/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Cardiovascular, Cell Biology, Developmental Biology, Hematology, Immunology and Inflammation, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection:
Phenotype: spleen hyperplasia [MP:0000693]| abnormal humoral immune response [MP:0001800]| abnormal B cell differentiation [MP:0002144]| abnormal class switch recombination [MP:0004816]| decreased B cell number [MP:0005017]| decreased B cell proliferation [MP:0005093]| decreased follicular B cell number [MP:0008174]| increased marginal zone B cell number [MP:0008181]| increased transitional stage B cell number [MP:0008189]| decreased IgG1 level [MP:0008495]| decreased IgG3 level [MP:0008498]| abnormal splenic cell ratio [MP:0008826]
Affected Gene: Fli1
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)