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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41882
Proper Citation: RRID:MMRRC_041882-UNC
Description: Mus musculus with name B6;SJL-Prop1df Tg(PROP1)884Sac/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Developmental Biology, Endocrine Deficiency, Models for Human Disease, Research Tools; Mutation Type: Transgenic ; Collection:
Phenotype: abnormal pituitary gland morphology [MP:0000633]| small ovary [MP:0001127]| absent corpus luteum [MP:0001134]| decreased body size [MP:0001265]| male infertility [MP:0001925]| female infertility [MP:0001926]| premature death [MP:0002083]| pituitary gland hypoplasia [MP:0002659]| absent ovarian follicles [MP:0002777]| decreased circulating follicle stimulating hormone level [MP:0002790]| small thyroid gland [MP:0002951]| abnormal pituitary gland development [MP:0003816]| decreased pituitary hormone level [MP:0003972]| decreased circulating thyroid-stimulating hormone level [MP:0005119]| decreased circulating growth hormone level [MP:0005120]| decreased circulating prolactin level [MP:0005121]| decreased follicle stimulating hormone level [MP:0005130]| decreased luteinizing hormone level [MP:0005132]| decreased thyroid-stimulating hormone level [MP:0005134]| decreased growth hormone level [MP:0005136]| abnormal enzyme/coenzyme activity [MP:0005584]| absent adenohypophysis [MP:0008320]| small adenohypophysis [MP:0008321]| absent somatotrophs [MP:0008330]| absent gonadotrophs [MP:0008336]| decreased thyrotroph cell number [MP:0008338]| proportional dwarf [MP:0008974]| small Rathke's pouch [MP:0013349]| abnormal Rathke's pouch development [MP:0013351]| abnormal Rathke's pouch apoptosis [MP:0013352]
Affected Gene: PROP1||Prop1|
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
