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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43505
Proper Citation: RRID:MMRRC_043505-UNC
Description: Mus musculus with name 129/Sv-Sp4tm3(Sp4)Krc/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Developmental Biology, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal hippocampus morphology [MP:0000807]| abnormal dentate gyrus morphology [MP:0000812]| abnormal locomotor behavior [MP:0001392]| hyperactivity [MP:0001399]| impaired coordination [MP:0001405]| decreased exploration in new environment [MP:0001417]| reduced long term potentiation [MP:0001473]| abnormal startle reflex [MP:0001486]| gliosis [MP:0002183]| reduced sensorimotor gating [MP:0002635]| decreased vertical activity [MP:0002757]| impaired passive avoidance behavior [MP:0004000]| abnormal spatial reference memory [MP:0008414]| impaired contextual conditioning behavior [MP:0009454]| impaired cued conditioning behavior [MP:0009456]| impaired spatial learning [MP:0012307]
Affected Gene: Sp4
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
