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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=46270
Proper Citation: RRID:MMRRC_046270-UCD
Description: Mus musculus with name B6.129-Tg(ITGAL-Ptprca)LP26Rasch Ptprctm1Holm/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Developmental Biology, Immunology and Inflammation, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection:
Phenotype: spleen hyperplasia [MP:0000693]| thymus hyperplasia [MP:0000708]| decreased thymocyte number [MP:0000715]| increased T cell derived lymphoma incidence [MP:0002024]| abnormal T cell differentiation [MP:0002145]| abnormal lymphopoiesis [MP:0002401]| abnormal B cell number [MP:0002458]| decreased T cell number [MP:0005018]| increased double-negative T cell number [MP:0005090]| decreased double-positive T cell number [MP:0005092]| decreased CD4-positive [MP:0008075]| alpha beta T cell number [MP:0008079]| abnormal T cell differentiation [MP:0002145]| abnormal interferon level [MP:0008750]| altered susceptibility to infection induced morbidity/mortality [MP:0009785]| decreased susceptibility to viral infection induced morbidity/mortality [MP:0009790]| increased susceptibility to viral infection induced morbidity/mortality [MP:0009791]| abnormal NK cell physiology [MP:0010766]
Affected Gene: |Ptprc|||
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
