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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=50436
Proper Citation: RRID:MMRRC_050436-UCD
Description: Mus musculus with name C57BL/6N-Zfp106tm1a(KOMP)Wtsi/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: KOMP
Phenotype: kyphosis [MP:0000160]| increased circulating calcium level [MP:0000194]| tremors [MP:0000745]| motor neuron degeneration [MP:0000938]| abnormal spinal cord morphology [MP:0000955]| small dorsal root ganglion [MP:0000964]| small L4 dorsal root ganglion [MP:0001021]| small L5 dorsal root ganglion [MP:0001024]| decreased body weight [MP:0001262]| weight loss [MP:0001263]| hypoactivity [MP:0001402]| impaired coordination [MP:0001405]| abnormal gait [MP:0001406]| limb grasping [MP:0001513]| impaired limb coordination [MP:0001524]| increased thermal nociceptive threshold [MP:0001973]| premature death [MP:0002083]| abnormal muscle physiology [MP:0002106]| gliosis [MP:0002183]| neurodegeneration [MP:0002229]| chromatolysis [MP:0002883]| abnormal soleus morphology [MP:0003081]| abnormal gastrocnemius morphology [MP:0003082]| abnormal redox activity [MP:0003186]| astrocytosis [MP:0003354]| abnormal muscle electrophysiology [MP:0004145]| positive geotaxis [MP:0005356]| abnormal axon morphology [MP:0005404]| axon degeneration [MP:0005405]| decreased mean corpuscular hemoglobin [MP:0005562]| abnormal mitochondrial physiology [MP:0006036]| abnormal lumbar dorsal root ganglion morphology [MP:0006404]| microgliosis [MP:0008918]| abnormal external male genitalia morphology [MP:0009199]| increased variability of skeletal muscle fiber size [MP:0009403]| centrally nucleated skeletal muscle fibers [MP:0009404]| decreased skeletal muscle fiber number [MP:0009406]| abnormal skeletal muscle fiber type ratio [MP:0009409]| skeletal muscle fiber atrophy [MP:0009413]| skeletal muscle atrophy [MP:0009417]| skeletal muscle fibrosis [MP:0009419]| decreased gastrocnemius weight [MP:0009422]| decreased soleus weight [MP:0009426]| decreased tibialis anterior weight [MP:0009428]| decreased grip strength [MP:0010053]| abnormal mitochondrial ATP synthesis coupled electron transport [MP:0010956]| increased spinal cord apoptosis [MP:0013182]
Affected Gene: Zfp106
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
