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URL: https://www.mmrrc.org/catalog/cellLineSDS.php?mmrrc_id=53143
Proper Citation: RRID:MMRRC_053143-UCD
Description: Mus musculus with name KOMP ES cell line Cbliftm1a(KOMP)Wtsi from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: KOMP
Phenotype: extramedullary hematopoiesis [MP:0000240]| abnormal hepatocyte morphology [MP:0000607]| decreased body weight [MP:0001262]| increased susceptibility to bacterial infection [MP:0002412]| abnormal megakaryocyte morphology [MP:0002417]| increased mean corpuscular volume [MP:0002590]| decreased erythrocyte cell number [MP:0002875]| decreased circulating glycerol level [MP:0003442]| maternal effect [MP:0003718]| decreased circulating iron level [MP:0004151]| increased T cell number [MP:0005015]| decreased circulating cholesterol level [MP:0005179]| decreased circulating serum albumin level [MP:0005419]| decreased circulating glucose level [MP:0005560]| increased blood urea nitrogen level [MP:0005565]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0009788]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0010330]| abnormal circulating lipoprotein level [MP:0011227]
Affected Gene: Cblif
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)