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URL: https://www.mmrrc.org/catalog/cellLineSDS.php?mmrrc_id=58313
Proper Citation: RRID:MMRRC_058313-UCD
Description: Mus musculus with name KOMP ES cell line Manftm1a(KOMP)Wtsi from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: KOMP
Phenotype: decreased body size [MP:0001265]| polydipsia [MP:0001426]| hyperglycemia [MP:0001559]| postnatal growth retardation [MP:0001732]| abnormal glucose homeostasis [MP:0002078]| decreased circulating insulin level [MP:0002727]| decreased pancreatic beta cell number [MP:0003339]| fetal growth retardation [MP:0004201]| abnormal fat pad morphology [MP:0005334]| abnormal neuronal migration [MP:0006009]| thin cerebral cortex [MP:0006254]| abnormal neurite morphology [MP:0008415]| abnormal cortical plate morphology [MP:0008439]| thin cortical plate [MP:0008441]| abnormal cortical intermediate zone morphology [MP:0008457]| slow postnatal weight gain [MP:0008489]| decreased pancreatic beta cell mass [MP:0009114]| decreased pancreatic islet number [MP:0009168]| abnormal pancreatic beta cell differentiation [MP:0009175]| abnormal neuronal stem cell morphology [MP:0012203]| increased pancreas apoptosis [MP:0013220]| abnormal translation [MP:0013272]| increased cerebral cortex cell density [MP:0020599]
Affected Gene: Manf
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)