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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=66730
Proper Citation: RRID:MMRRC_066730-JAX
Description: Mus musculus with name STOCK Adora1tm1Jgsc Adora3tm1Jbsn Adora2atm1Jfc Adora2btm1Till/ReiMmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Endocrine Deficiency, Metabolism, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal response/metabolism to endogenous compounds [MP:0003638]| increased susceptibility to kidney reperfusion injury [MP:0004041]| increased circulating creatinine level [MP:0005553]| absent tubuloglomerular feedback response [MP:0011297]| decreased airway responsiveness [MP:0002335]| abnormal mast cell physiology [MP:0002423]| abnormal nociception after inflammation [MP:0002736]| decreased systemic arterial blood pressure [MP:0002843]| increased coronary flow rate [MP:0003022]| decreased myocardial infarction size [MP:0003038]| abnormal response/metabolism to endogenous compounds [MP:0003638]| decreased susceptibility to kidney reperfusion injury [MP:0004042]| decreased acute inflammation [MP:0005087]| ocular hypotension [MP:0005260]| decreased circulating creatinine level [MP:0005554]| decreased tumor necrosis factor secretion [MP:0008561]| impaired neutrophil recruitment [MP:0008719]| abnormal mast cell degranulation [MP:0008763]| heart right ventricle hypertrophy [MP:0000276]| abnormal pulmonary artery morphology [MP:0000484]| hypoactivity [MP:0001402]| abnormal sclera morphology [MP:0002698]| vascular smooth muscle hypertrophy [MP:0002975]| myopia [MP:0003100]| abnormal locomotor activation [MP:0003313]| pulmonary hypertension [MP:0003548]| abnormal lung vasculature morphology [MP:0004007]| decreased cerebral infarction size [MP:0006058]| decreased susceptibility to ischemic brain injury [MP:0006059]| decreased physiological sensitivity to xenobiotic [MP:0008874]| impaired behavioral response to addictive substance [MP:0009750]| increased right ventricle systolic pressure [MP:0010758]| decreased susceptibility to induction of seizure by inducing agent [MP:0012348]| increased susceptibility to type I hypersensitivity reaction [MP:0005596]| increased interleukin-6 secretion [MP:0008705]| decreased physiological sensitivity to xenobiotic [MP:0008874]| increased sensitivity to induced morbidity/mortality [MP:0009763]| abnormal cellular extravasation [MP:0009858]| impaired adaptive thermogenesis [MP:0011049]
Affected Gene: |Adora1||Adora2b||Adora2a|Adora3|
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No rating or validation information has been found for STOCK Adora1tm1Jgsc Adora3tm1Jbsn Adora2atm1Jfc Adora2btm1Till/ReiMmjax.
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)