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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=68229
Proper Citation: RRID:MMRRC_068229-JAX
Description: Mus musculus with name B6J.129X1-Ier3tm1Mxw/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cardiovascular, Cell Biology, Dermatology, Hematology, Immunology and Inflammation, Metabolism, Models for Human Disease, Neurobiology, Obesity, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: increased neutrophil cell number [MP:0000219]| increased granulocyte number [MP:0000322]| impaired macrophage phagocytosis [MP:0001798]| abnormal macrophage physiology [MP:0002451]| increased systemic arterial blood pressure [MP:0002842]| delayed wound healing [MP:0002908]| decreased incidence of tumors by chemical induction [MP:0004502]| decreased regulatory T cell number [MP:0004974]| abnormal response to infection [MP:0005025]| increased susceptibility to parasitic infection [MP:0005027]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005591]| decreased vasodilation [MP:0008539]| decreased susceptibility to induced colitis [MP:0008556]| abnormal tumor necrosis factor secretion [MP:0008751]| abnormal interleukin level [MP:0008752]| abnormal tumor necrosis factor level [MP:0008872]| abnormal physiological response to xenobiotic [MP:0010155]| abnormal intestine physiology [MP:0010219]
Affected Gene: Ier3
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
