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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=69519
Proper Citation: RRID:MMRRC_069519-UNC
Description: Mus musculus with name 129S1.Cg-Fbn1tm3Rmz/RmzMmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cardiovascular, Dermatology, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection:
Phenotype: decreased bone mineral density [MP:0000063]| abnormal trabecular bone morphology [MP:0000130]| abnormal rib morphology [MP:0000150]| overexpanded pulmonary alveoli [MP:0001183]| abnormal respiration [MP:0001943]| abnormal diaphragm morphology [MP:0002279]| abnormal intercostal muscle morphology [MP:0002280]| abnormal bone marrow cell morphology/development [MP:0002398]| abnormal bone remodeling [MP:0002998]| abnormal aorta elastic fiber morphology [MP:0003211]| diaphragmatic hernia [MP:0003924]| decreased bone mass [MP:0004016]| long ribs [MP:0004671]| hemothorax [MP:0005243]| hemopericardium [MP:0005244]| abnormal skin tensile strength [MP:0005275]| aortic aneurysm [MP:0006278]| decreased trabecular bone thickness [MP:0009346]| abnormal aorta elastic tissue morphology [MP:0009862]| abnormal aorta tunica media morphology [MP:0009873]| ascending aorta dilation [MP:0010470]| abnormal bone trabecula morphology [MP:0010867]| decreased bone trabecula number [MP:0010869]| decreased bone volume [MP:0010876]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011099]| lethality throughout fetal growth and development [MP:0011109]
Affected Gene: Fbn1
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
