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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=69611
Proper Citation: RRID:MMRRC_069611-JAX
Description: Mus musculus with name STOCK Gpd2tm1Tka Slc25a13tm1Lct/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Metabolism, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| abnormal gluconeogenesis [MP:0003383]| increased circulating glycerol level [MP:0003443]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| abnormal urine homeostasis [MP:0009643]| hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| decreased body size [MP:0001265]| abnormal eating behavior [MP:0001431]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| decreased insulin secretion [MP:0003059]| increased circulating glycerol level [MP:0003443]| increased circulating cholesterol level [MP:0005178]| decreased oxygen consumption [MP:0005290]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| abnormal triiodothyronine level [MP:0005472]| increased circulating thyroxine level [MP:0005477]| increased circulating triiodothyronine level [MP:0005480]| increased body temperature [MP:0005533]| decreased brown fat cell lipid droplet size [MP:0009125]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| impaired adaptive thermogenesis [MP:0011049]| decreased brown adipose tissue mass [MP:0014169]
Affected Gene: |Gpd2||Slc25a13
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No rating or validation information has been found for STOCK Gpd2tm1Tka Slc25a13tm1Lct/Mmjax.
Issue
Warning. Researchers have noted that this genotype does not sufficiently model human citrullinemia.
Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
