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Proper Citation: RRID:MGI:2175062
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: absent otic vesicle, decreased forebrain size, absent hippocampal commissure, abnormal midbrain-hindbrain boundary development, absent pituitary infundibular stalk, absent Rathke's pouch, abnormal septum pellucidum morphology, microphthalmia, enophthalmos, olfactory bulb hypoplasia, abnormal telencephalon morphology, absent corpus callosum, small vomeronasal organ, anophthalmia, abnormal eye morphology, abnormal telencephalon morphology, absent anterior commissure, abnormal olfactory epithelium morphology, abnormal nasal cavity morphology, abnormal optic vesicle formation, abnormal nasal pit morphology, abnormal hypothalamus morphology, decreased embryonic neuroepithelium thickness, bifurcated Rathke's pouch, abnormal optic cup morphology, abnormal craniofacial morphology, short snout, microcephaly, abnormal telencephalon development, decreased forebrain size, abnormal nasal placode morphology, small embryonic telencephalon, small adenohypophysis, abnormal forebrain development, abnormal frontonasal prominence morphology, anophthalmia, small embryonic telencephalon, postnatal lethality, incomplete penetrance, neonatal lethality, incomplete penetrance
Affected Gene: Hesx1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI