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Proper Citation: RRID:MGI:2450095
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal capillary morphology, skin edema, decreased hematocrit, decreased hemoglobin content, increased mean corpuscular volume, absent mesangial cell, abnormal aorta smooth muscle morphology, aorta dilation, respiratory failure, abnormal urinary bladder morphology, lethality throughout fetal growth and development, incomplete penetrance, abnormal artery morphology, small liver, macrocytic anemia, kidney microaneurysm, abnormal vascular endothelial cell morphology, abnormal glial cell morphology, mesangial cell hypoplasia, hemorrhage, abnormal renal glomerulus morphology, abnormal blood vessel morphology, small kidney, perinatal lethality, incomplete penetrance, abnormal pericyte morphology, abnormal placenta vasculature, abnormal placental labyrinth vasculature morphology, abnormal trophoblast layer morphology, abnormal heart right ventricle morphology, abnormal coronary vessel morphology, congestive heart failure, erythroblastosis, enlarged heart, dilated heart right ventricle, dilated heart left ventricle, thrombocytopenia, abnormal kidney morphology, abnormal blood vessel morphology, increased vascular endothelial cell number
Affected Gene: Pdgfb
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI