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Proper Citation: RRID:MGI:3608331
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal duodenum morphology, abnormal metallophilic macrophage morphology, steatorrhea, decreased Peyer's patch number, abnormal spleen B cell follicle morphology, abnormal leukocyte migration, increased enterocyte cell number, absent spleen, abnormal mesenteric lymph node morphology, abnormal small intestine morphology, spleen atrophy, decreased CD4-positive, alpha beta T cell number, abnormal small intestinal villus morphology, abnormal intestinal mucosa morphology, increased leukocyte cell number, abnormal jejunum morphology, decreased plasma cell number, diarrhea, abnormal spleen red pulp morphology, absent spleen marginal zone, decreased circulating triglyceride level, small Peyer's patches, postnatal lethality, incomplete penetrance, delayed intestine development, abnormal intestine morphology, abnormal gut-associated lymphoid tissue morphology, abnormal intestinal peristalsis, abnormal jejunum crypts of Lieberkuhn morphology, small cecum, small spleen, abnormal spleen periarteriolar lymphoid sheath morphology
Affected Gene: Nkx2-3
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
