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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=362
Proper Citation: RRID:MMRRC_000362-UNC
Description: Mus musculus with name B6.129X1-Trp53tm1Ldo/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer; Mutation Type: Targeted Mutation ; Collection:
Phenotype: decreased bone mineral density [MP:0000063]| kyphosis [MP:0000160]| lordosis [MP:0000162]| sparse hair [MP:0000416]| delayed hair regrowth [MP:0000423]| liver hypoplasia [MP:0000600]| abnormal mammary gland development [MP:0000628]| spleen hypoplasia [MP:0000694]| thin dermal layer [MP:0001244]| weight loss [MP:0001263]| testis hypoplasia [MP:0001940]| increased tumor incidence [MP:0002020]| increased T cell derived lymphoma incidence [MP:0002024]| increased sarcoma incidence [MP:0002032]| increased lung adenoma incidence [MP:0002048]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| muscular atrophy [MP:0002269]| delayed wound healing [MP:0002908]| decreased liver weight [MP:0003402]| renal hypoplasia [MP:0003446]| premature aging [MP:0003786]| decreased kidney weight [MP:0003918]| decreased circulating insulin-like growth factor I level [MP:0004701]| decreased skeletal muscle mass [MP:0004819]| decreased testis weight [MP:0004852]| decreased spleen weight [MP:0004953]| lethargy [MP:0005202]| abnormal cell physiology [MP:0005621]| decreased subcutaneous adipose tissue amount [MP:0008844]| abnormal physiological response to xenobiotic [MP:0008872]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009766]
Affected Gene: Trp53
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
