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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=11536
Proper Citation: RRID:MMRRC_011536-UNC
Description: Mus musculus with name B6;129-Aregtm1Dle Egftm1Dle Tgfatm1Unc/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Cell Biology, Dermatology, Developmental Biology, Immunology and Inflammation, Internal/Organ, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: waved hair [MP:0000410]| alopecia [MP:0000414]| abnormal small intestine morphology [MP:0000496]| abnormal branching of the mammary ductal tree [MP:0000662]| dermatitis [MP:0001194]| spontaneous skin ulceration [MP:0001209]| decreased body weight [MP:0001262]| weight loss [MP:0001263]| curly vibrissae [MP:0001274]| microphthalmia [MP:0001297]| eyelids open at birth [MP:0001302]| corneal opacity [MP:0001314]| postnatal growth retardation [MP:0001732]| duodenal lesions [MP:0002580]| abnormal ileum morphology [MP:0002581]| abnormal intestinal goblet cell morphology [MP:0003449]| abnormal small intestine crypts of Lieberkuhn morphology [MP:0004841]| abnormal mammary gland growth during pregnancy [MP:0006269]| hypolactation [MP:0013716]| abnormal adipose tissue distribution [MP:0000013]| abnormal hair follicle morphology [MP:0000377]| abnormal hair follicle orientation [MP:0000383]| waved hair [MP:0000410]| alopecia [MP:0000414]| abnormal small intestine morphology [MP:0000496]| abnormal branching of the mammary ductal tree [MP:0000662]| dermatitis [MP:0001194]| spontaneous skin ulceration [MP:0001209]| decreased body weight [MP:0001262]| weight loss [MP:0001263]| curly vibrissae [MP:0001274]| kinked vibrissae [MP:0001278]| microphthalmia [MP:0001297]| eyelids open at birth [MP:0001302]| cataract [MP:0001304]| corneal opacity [MP:0001314]| corneal scarring [MP:0001316]| abnormal iris morphology [MP:0001322]| abnormal eyelid morphology [MP:0001340]| disheveled coat [MP:0001511]| postnatal growth retardation [MP:0001732]| abnormal eye morphology [MP:0002092]| duodenal lesions [MP:0002580]| abnormal ileum morphology [MP:0002581]| abnormal intestinal goblet cell morphology [MP:0003449]| abnormal eyelid aperture [MP:0003671]| abnormal hair shaft morphology [MP:0003809]| abnormal hair medulla [MP:0003812]| absent Descemet membrane [MP:0004285]| small mandible [MP:0004592]| abnormal small intestine crypts of Lieberkuhn morphology [MP:0004841]| abnormal anterior eye segment morphology [MP:0005193]| abnormal mammary gland growth during pregnancy [MP:0006269]| ruptured lens capsule [MP:0008841]| retinal neovascularization [MP:0008852]| abnormal eyelid development [MP:0009651]| absent eye anterior chamber [MP:0010709]| Meibomian gland hypoplasia [MP:0013389]| eyelid hyperplasia [MP:0013396]| hypolactation [MP:0013716]| orbicularis oculi muscle hypoplasia [MP:0030175]| waved hair [MP:0000410]| alopecia [MP:0000414]| abnormal small intestine morphology [MP:0000496]| abnormal branching of the mammary ductal tree [MP:0000662]| dermatitis [MP:0001194]| spontaneous skin ulceration [MP:0001209]| decreased body weight [MP:0001262]| weight loss [MP:0001263]| curly vibrissae [MP:0001274]| microphthalmia [MP:0001297]| eyelids open at birth [MP:0001302]| corneal opacity [MP:0001314]| postnatal growth retardation [MP:0001732]| no abnormal phenotype detected [MP:0002169]| duodenal lesions [MP:0002580]| abnormal ileum morphology [MP:0002581]| abnormal intestinal goblet cell morphology [MP:0003449]| abnormal small intestine crypts of Lieberkuhn morphology [MP:0004841]| abnormal mammary gland growth during pregnancy [MP:0006269]| hypolactation [MP:0013716]
Affected Gene: |Areg||Egf||Tgfa
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)