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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=11869
Proper Citation: RRID:MMRRC_011869-UNC
Description: Mus musculus with name STOCK Smarca4tm1Mag/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Developmental Biology, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal liver morphology [MP:0000598]| absent CD8-positive [MP:0000727]| alpha-beta T cells [MP:0000914]| exencephaly [MP:0001823]| thymus hypoplasia [MP:0001825]| arrested T cell differentiation [MP:0001883]| increased mammary adenocarcinoma incidence [MP:0002020]| increased tumor incidence [MP:0002083]| premature death [MP:0002145]| abnormal T cell differentiation [MP:0002429]| abnormal blood cell morphology/development [MP:0002447]| abnormal erythrocyte morphology [MP:0003667]| increased hemangiosarcoma incidence [MP:0003789]| increased osteosarcoma incidence [MP:0005089]| decreased double-negative T cell number [MP:0005092]| decreased double-positive T cell number [MP:0008075]| decreased CD4-positive [MP:0008770]| alpha beta T cell number [MP:0010299]| decreased survivor rate [MP:0010320]| increased mammary gland tumor incidence [MP:0011086]| increased pituitary gland tumor incidence [MP:0011094]| postnatal lethality [MP:0011098]
Affected Gene: Smarca4
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)