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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=17244
Proper Citation: RRID:MMRRC_017244-UNC
Description: Mus musculus with name C.129(Cg)-Rag1tm1Bal Igk-Jtm2Mwg Igh-Jtm2(3H9-VDJ*)Mwg/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Immunology and Inflammation, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: spleen hypoplasia [MP:0000694]| increased anti-double stranded DNA antibody level [MP:0004762]| decreased B cell number [MP:0005017]| abnormal marginal zone B cell morphology [MP:0008180]| increased marginal zone B cell number [MP:0008181]| abnormal B cell receptor editing [MP:0008766]| arrested T cell differentiation [MP:0001825]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| premature death [MP:0002083]| abnormal kidney morphology [MP:0002135]| abnormal CD4-positive [MP:0002432]| alpha beta T cell morphology [MP:0002599]| increased mean platelet volume [MP:0002703]| abnormal renal tubule morphology [MP:0002962]| increased urine protein level [MP:0003179]| thrombocytopenia [MP:0004505]| decreased renal glomerulus number [MP:0005048]| abnormal thrombosis [MP:0008075]| decreased CD4-positive [MP:0008078]| alpha beta T cell number [MP:0009446]| increased CD8-positive [MP:0009549]
Affected Gene: |Igk-J||||Rag1
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No rating or validation information has been found for C.129(Cg)-Rag1tm1Bal Igk-Jtm2Mwg Igh-Jtm2(3H9-VDJ*)Mwg/Mmnc.
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
