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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41200
Proper Citation: RRID:MMRRC_041200-MU
Description: Mus musculus with name B6.Cg-Nfatc2tm1Rao Tg(APPswe,PSEN1dE9)85Dbo/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Immunology and Inflammation, Neurobiology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal T cell differentiation [MP:0002145]| abnormal double-negative T cell morphology [MP:0002407]| abnormal mast cell physiology [MP:0002423]| abnormal B cell physiology [MP:0002459]| increased T cell apoptosis [MP:0006413]| decreased tumor necrosis factor secretion [MP:0008561]| decreased interleukin-13 secretion [MP:0008673]| decreased interleukin-2 secretion [MP:0008688]| decreased interleukin-4 secretion [MP:0008700]
Affected Gene: Nfatc2||APPswe||APP|PSEN1
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No rating or validation information has been found for B6.Cg-Nfatc2tm1Rao Tg(APPswe,PSEN1dE9)85Dbo/Mmmh.
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
