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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43537
Proper Citation: RRID:MMRRC_043537-UNC
Description: Mus musculus with name B6.Cg-Cdkn2atm3.1Nesh Tyrc-2J/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Cell Biology, Dermatology, Hematology, Immunology and Inflammation, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: absent hair follicle melanin granules [MP:0000394]| abnormal retinal photoreceptor morphology [MP:0001004]| absent skin pigmentation [MP:0001189]| abnormal keratinocyte apoptosis [MP:0001224]| abnormal retina morphology [MP:0001325]| retinal degeneration [MP:0001326]| decreased retinal photoreceptor cell number [MP:0001327]| abnormal vision [MP:0002090]| no abnormal phenotype detected [MP:0002169]| decreased susceptibility to bacterial infection [MP:0002411]| abnormal iridocorneal angle [MP:0004221]| iris synechia [MP:0004222]| absent Schlemm's canal [MP:0004226]| increased cellular sensitivity to ionizing radiation [MP:0004227]| abnormal melanosome morphology [MP:0005075]| absent coat pigmentation [MP:0005171]| abnormal aqueous drainage system morphology [MP:0005198]| abnormal trabecular meshwork morphology [MP:0005203]| abnormal retinal ganglion layer morphology [MP:0005241]| abnormal eye physiology [MP:0005253]| abnormal intraocular pressure [MP:0005257]| ocular albinism [MP:0006159]| decreased circulating interferon-alpha level [MP:0008574]| decreased circulating interferon-beta level [MP:0008576]| abnormal vitamin A metabolism [MP:0011233]| anterior iris synechia [MP:0011481]| decreased a wave amplitude [MP:0012143]| decreased b wave amplitude [MP:0012144]
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)