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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=65937
Proper Citation: RRID:MMRRC_065937-JAX
Description: Mus musculus with name B6.Cg-Tia1tm1Andp Smn1tm5(Smn1/SMN2)Mrph/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Cardiovascular, Cell Biology, Developmental Biology, Immunology and Inflammation, Internal/Organ, Models for Human Disease, Neurobiology, Reproduction, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: decreased bone mineral density [MP:0000063]| abnormal neuromuscular synapse morphology [MP:0001053]| epidermal necrosis [MP:0001220]| decreased body size [MP:0001265]| abnormal blood vessel morphology [MP:0001614]| hyperresponsive to tactile stimuli [MP:0002738]| abnormal endplate potential [MP:0002914]| abnormal synaptic transmission [MP:0003635]| enhanced coordination [MP:0003858]| decreased thermal nociceptive threshold [MP:0003998]| abnormal miniature endplate potential [MP:0004835]| decreased heart rate [MP:0005333]| hyperalgesia [MP:0005407]| decreased skeletal muscle fiber size [MP:0009400]| decreased bone mineral content [MP:0010124]| embryonic lethality [MP:0011092]| complete penetrance [MP:0013178]| increased neutrophil cell number [MP:0000219]| postnatal growth retardation [MP:0001732]| abnormal macrophage physiology [MP:0002451]| arthritis [MP:0002993]| increased susceptibility to endotoxin shock [MP:0008735]| postnatal lethality [MP:0011086]
Affected Gene: Tia1||SMN2|Smn1|
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
