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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=69611
Proper Citation: RRID:MMRRC_069611-JAX
Description: Mus musculus with name STOCK Gpd2tm1Tka Slc25a13tm1Lct/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Metabolism, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| abnormal gluconeogenesis [MP:0003383]| increased circulating glycerol level [MP:0003443]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| abnormal urine homeostasis [MP:0009643]| hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| decreased body size [MP:0001265]| abnormal eating behavior [MP:0001431]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| decreased insulin secretion [MP:0003059]| increased circulating glycerol level [MP:0003443]| increased circulating cholesterol level [MP:0005178]| decreased oxygen consumption [MP:0005290]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| abnormal triiodothyronine level [MP:0005472]| increased circulating thyroxine level [MP:0005477]| increased circulating triiodothyronine level [MP:0005480]| increased body temperature [MP:0005533]| decreased brown fat cell lipid droplet size [MP:0009125]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| impaired adaptive thermogenesis [MP:0011049]| decreased brown adipose tissue mass [MP:0014169]
Affected Gene: |Gpd2||Slc25a13
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No rating or validation information has been found for STOCK Gpd2tm1Tka Slc25a13tm1Lct/Mmjax.
Issue
Warning. Researchers have noted that this genotype does not sufficiently model human citrullinemia.
Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
