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URL: http://www.wormbase.org/db/get?name=WBStrain00008304
Proper Citation: RRID:WB-STRAIN:WBStrain00008304
Description: Caenorhabditis elegans with name sod-1(rt451[sod-1(G85R C)]) II. from WB.
Species: Caenorhabditis elegans
Synonyms: sod-1(rt451[sod-1(G85R C)]) II.
Notes: Made_by: Saba Baskoylu|"Superficially wild-type with increased sensitivity to paraquat in multiple assays. Can be maintained 15-25C. rt451 is CRISPR/Cas9 engineered G85R missense mutation in endogenous sod-1 locus mimicking human ALS SOD1 model. Reference: Baskoylu SN, et al. PLoS Genet. 2018;14(10):e1007682. NOTE: A micropublication on these strains (PMID: 33474528) incorrectly described sod-1(rt448) as the G85R mutant version and sod-1(rt449) as the control. Additionally, the strains list in the paper also incorrectly describes rt449 as sod-1 [G85RC]. The correct descriptions are that rt448 is the wild-type control, rt449 is the sod-1 [G93AC] mutant version, and rt451 is the sod-1 [G85RC] mutant version.]"|"[250107 skd] genotype updated as sod-1(rt451[sod-1G85RC]) II. was sod-1(rt451[sod-1G85R]) II."
Affected Gene: WBGene00004930(sod-1)
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Source: Integrated Animals
Source Database: WormBase (WB)
