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URL: http://www.wormbase.org/db/get?name=WBStrain00050449
Proper Citation: RRID:WB-STRAIN:WBStrain00050449
Description: Caenorhabditis elegans with name ogt-1(dr84[ogt-1::GFP] dr91[H612A]) III. from WB.
Species: Caenorhabditis elegans
Synonyms: ogt-1(dr84[ogt-1::GFP] dr91[H612A]) III.
Notes: drIs4 [gpdh-1p::GFP + col-12p::DsRed] IV. H612A mutation introduced into the endogenous ogt-1 locus tagged with C-terminal GFP. OGT-1(H612A)::GFP is expressed ubiquitously in somatic tissues with a nuclear localization. The H612A mutation decreases, but does not completely ablate, the O-GlcNAcylation activity of OGT-1 as measured by the RL2 O-GlcNAc antibody. Sanger sequence confirmed. Reference: Urso SJ, et al. (2020). The O-GlcNAc transferase OGT is a conserved and essential regulator of the cellular and organismal response to hypertonic stress. bioRxiv, 2020.2005.2001.072033.|"Generated from papers flagged positive during the last month for data type afp_otherstrain and contains genotype and gene data."|"Made_by: Sarel Urso"
Affected Gene: WBGene00003858(ogt-1)
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Source: WormBase (RRID:SCR_003098)
Description: Central data repository for nematode biology including complete genomic sequence, gene predictions and orthology assignments from range of related nematodes.Data concerning genetics, genomics and biology of C. elegans and related nematodes. Derived from initial ACeDB database of C. elegans genetic and sequence information, WormBase includes genomic, anatomical and functional information of C. elegans, other Caenorhabditis species and other nematodes. Maintains public FTP site where researchers can find many commonly requested files and datasets, WormBase software and prepackaged databases.
URL: http://www.wormbase.org
Source Database: WormBase (WB)
