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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_3714
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Population: Caucasian., Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Proper citation: CLS Cat# 305126, RRID:CVCL_3714 Copy
https://web.expasy.org/cellosaurus/CVCL_0298
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Senescence: Capable of at least 57 PDL (JCRB=IFO50074)., Population: Caucasian.
Proper citation: CLS Cat# 305065, RRID:CVCL_0298 Copy
https://web.expasy.org/cellosaurus/CVCL_3009
Organism: Macaca mulatta (Rhesus macaque)
Category: Spontaneously immortalized cell line
Comments: Donor information: Derived from the trypsinization of a pool of kidneys from 6 adult rhesus monkeys., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV) (PubMed=16494729)., Group: Patented cell line., Group: Non-human primate cell line.
Proper citation: CLS Cat# 305149, RRID:CVCL_3009 Copy
https://web.expasy.org/cellosaurus/CVCL_5792
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Anecdotal: Cell line name is derived from the name of the first author of the original paper., Characteristics: Able to grow under reduced serum conditions (1% FBS) (PubMed=15591520).
Proper citation: CLS Cat# 305039, RRID:CVCL_5792 Copy
Misidentified Discontinued
https://web.expasy.org/cellosaurus/CVCL_3845
Organism: Chlorocebus pygerythrus (Vervet monkey)
Category: Spontaneously immortalized cell line
Comments: Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Virology: Susceptible to infection by many viruses (arboviruses, reoviruses, rotaviruses, etc.)., Problematic cell line: Misidentified. Originally thought to be of Rhesus macaque origin but found to be from African Green monkey (PubMed=4043530; PubMed=20143388) and more precisely from Chlorocebus pygerythrus (PubMed=34737324).., Group: Non-human primate cell line.
Proper citation: CLS Cat# 305007, RRID:CVCL_3845 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_4U18
Organism: Homo sapiens (Human)
Category: Hybrid cell line
Comments: Characteristics: Can differentiate when cultured in mitogen-free medium. The cells may be used to study developmental regulation of cardiomyocytes (Millipore=SCC109)., Characteristics: Hybrid of adult ventricular cardiomiocytes with a SV40 transformed, uridine auxotroph human fibroblast cell line devoid of mitochondrial DNA (PubMed=15913645)., Group: Patented cell line.
Proper citation: CLS Cat# 305215, RRID:CVCL_4U18 Copy
https://web.expasy.org/cellosaurus/CVCL_5719
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: CLS Cat# 400391, RRID:CVCL_5719 Copy
https://web.expasy.org/cellosaurus/CVCL_B288
Organism: Mus musculus (Mouse)
Disease: Mouse colon adenocarcinoma
Category: Cancer cell line
Comments: Caution: The authors of PubMed=25434994 indicate that they have sequenced the mitochondrial genome of the 'rat' cell line MCA38. Their submitted DNA sequence (KM820832.1) is indeed a rat sequence but is labelled as originating from 'rat isolate 406'., Miscellaneous: Comparative analysis of MC38 cells obtained from Kerafast (MC38-K) and from Leiden University Medical Center (MC38-L) shows major differences in term of mutations and mRNA expression (PubMed=36969213).
Proper citation: CLS Cat# 305223, RRID:CVCL_B288 Copy
https://web.expasy.org/cellosaurus/CVCL_3855
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: CLS Cat# 300487, RRID:CVCL_3855 Copy
https://web.expasy.org/cellosaurus/CVCL_5J48
Organism: Mus musculus (Mouse)
Disease: Mouse gastric carcinoma
Category: Cancer cell line
Proper citation: CLS Cat# 300652, RRID:CVCL_5J48 Copy
https://web.expasy.org/cellosaurus/CVCL_B063
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: CLS Cat# 305182, RRID:CVCL_B063 Copy
https://web.expasy.org/cellosaurus/CVCL_2665
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Anecdotal: OKT3 was the first monoclonal antibody to be approved for clinical use in humans., Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized teplizumab (MGA031) therapeutic antibody., Biotechnology: The monoclonal antibody produced by this hybridoma was used as an immunosuppressant drug under the name Muromonab-CD3 (Orthoclone OKT3)., Group: Patented cell line.
Proper citation: CLS Cat# 300499, RRID:CVCL_2665 Copy
https://web.expasy.org/cellosaurus/CVCL_2664
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: CLS Cat# 300500, RRID:CVCL_2664 Copy
https://web.expasy.org/cellosaurus/CVCL_5845
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: CLS Cat# 400100, RRID:CVCL_5845 Copy
Discontinued Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0347
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Senescence: Capable of attaining 58 population doublings before the onset of senescence (ATCC=CCL-186)., Population: Caucasian., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: International Histocompatibility Workshop cell lines., Part of: ENCODE project common cell types; tier 2.
Proper citation: CLS Cat# 305216, RRID:CVCL_0347 Copy
https://web.expasy.org/cellosaurus/CVCL_G363
Organism: Mus musculus (Mouse)
Disease: Adenocarcinoma of the mouse pulmonary system
Category: Cancer cell line
Proper citation: CLS Cat# 300472, RRID:CVCL_G363 Copy
https://web.expasy.org/cellosaurus/CVCL_1362
Organism: Homo sapiens (Human)
Disease: Hodgkin lymphoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: CLS Cat# 300201, RRID:CVCL_1362 Copy
Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_2898
Organism: Bos taurus (Bovine)
Category: Finite cell line
Comments: Virology: Persistently infected by bovine viral diarrhea virus (BVDV) (PubMed=7989438)., Characteristics: Susceptible to infection by Ehrlichia ruminantium (CelloPub=CLPUB00632)., Characteristics: FGF dependent.
Proper citation: CLS Cat# 302159, RRID:CVCL_2898 Copy
https://web.expasy.org/cellosaurus/CVCL_6974
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Discontinued: Thermo Fisher/Invitrogen; Catalog number R620-07., Characteristics: The use of recombinant protein expression vectors containing the EBV oriP in cell lines stably expressing EBV's EBNA1 protein significantly increases recombinant protein yield.
Proper citation: CLS Cat# 300264, RRID:CVCL_6974 Copy
https://web.expasy.org/cellosaurus/CVCL_UR41
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American.
Proper citation: CLS Cat# 300919, RRID:CVCL_UR41 Copy
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