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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_XE54
Organism: Homo sapiens (Human)
Disease: Childhood hepatocellular carcinoma
Category: Cancer cell line
Comments: Karyotypic information: Has lost chromosome Y., Characteristics: Transduced with a Cas9-FLAG-Neo construct., Population: African American.
Proper citation: RRID:CVCL_XE54 Copy
https://web.expasy.org/cellosaurus/CVCL_0327
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Secretes several liver products including albumin, alpha-fetoprotein, alpha 1-antitrypin and amylase (ECACC=92110305).
Proper citation: NCBI_Iran Cat# C517, RRID:CVCL_0327 Copy
https://web.expasy.org/cellosaurus/CVCL_0328
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Proper citation: KCLB Cat# 22026, RRID:CVCL_0328 Copy
https://web.expasy.org/cellosaurus/CVCL_0327
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Secretes several liver products including albumin, alpha-fetoprotein, alpha 1-antitrypin and amylase (ECACC=92110305).
Proper citation: ATCC Cat# CRL-1830, RRID:CVCL_0327 Copy
https://web.expasy.org/cellosaurus/CVCL_B5VY
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_B5VY Copy
https://web.expasy.org/cellosaurus/CVCL_A5BH
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Proper citation: RRID:CVCL_A5BH Copy
https://web.expasy.org/cellosaurus/CVCL_0329
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Proper citation: RRID:CVCL_0329 Copy
https://web.expasy.org/cellosaurus/CVCL_B6AL
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Proper citation: RRID:CVCL_B6AL Copy
https://web.expasy.org/cellosaurus/CVCL_B6AP
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Proper citation: RRID:CVCL_B6AP Copy
https://web.expasy.org/cellosaurus/CVCL_B5W1
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_B5W1 Copy
https://web.expasy.org/cellosaurus/CVCL_RA18
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Reporter cell line, transduced with the LV-eGFP-PGKp-Puro vector encoding for eGFP under control of the spleen focus-forming virus (SFFV) promoter and the PuroR gene under the control of the mouse PGK promoter (Imanis=CL128).
Proper citation: RRID:CVCL_RA18 Copy
https://web.expasy.org/cellosaurus/CVCL_B6AT
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Proper citation: RRID:CVCL_B6AT Copy
https://web.expasy.org/cellosaurus/CVCL_0327
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Secretes several liver products including albumin, alpha-fetoprotein, alpha 1-antitrypin and amylase (ECACC=92110305).
Proper citation: BCRC Cat# 60051, RRID:CVCL_0327 Copy
https://web.expasy.org/cellosaurus/CVCL_XE53
Organism: Homo sapiens (Human)
Disease: Childhood hepatocellular carcinoma
Category: Cancer cell line
Comments: Karyotypic information: Has lost chromosome Y., Characteristics: Transduced with a Cas9-FLAG-Neo construct., Population: African American.
Proper citation: RRID:CVCL_XE53 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_9720
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Miscellaneous: This cell line is exclusively produced and controlled by Biopredic International and owned by Inserm. BioPredic sells undifferentiated cell line (HPR101) that can be expanded, passaged, and frozen in-house to prepare a cell bank and differentiated ready-to-use cells, HPR116 (Cellosaurus=CVCL_WL73) that can be used immediately or in a few days after thawing, as a single-use disposable product (Biopredic)., Anecdotal: The 'RG' in the cell name stands for 'Rumin' and 'Gripon', the two scientists that were influential in the establishment of this cell line., Characteristics: Cell line main applications are sugar and lipid metabolism, physiopathology; drug metabolism and toxicology and viral infection., Characteristics: Can be induced to differentiate into hepatocyte-like cells by exposure to DMSO., Group: Patented cell line.
Proper citation: RRID:CVCL_9720 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_DC15
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Acts through the activation of a luciferase reporter gene which is under the control of dioxin-response elements (DREs) from mouse Cyp1a1 gene., Biotechnology: Can be used for bioassays to detect dioxin/TCDD-like compounds., Group: Patented cell line.
Proper citation: RRID:CVCL_DC15 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_M177
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Virology: Inducibly expresses a hepatitis B virus (HBV) genome under the control of a tet operator/CMV promoter. Upon removal of tetracycline the cell line produces viral RNA and secrete virus-like particles into the supernatant., Biotechnology: Used in a bioassay that permits the large-scale screening of compound libraries for inhibitors of HBV replication., Population: Caucasian., Group: Patented cell line.
Proper citation: RRID:CVCL_M177 Copy
https://web.expasy.org/cellosaurus/CVCL_DI40
Organism: Homo sapiens (Human)
Disease: Childhood hepatocellular carcinoma
Category: Cancer cell line
Comments: Karyotypic information: Has lost chromosome Y., Population: African American.
Proper citation: RRID:CVCL_DI40 Copy
https://web.expasy.org/cellosaurus/CVCL_XI49
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Characteristics: Compared to the parent cell line, has improved liver functionality. Drug metabolism is highly improved. Culturing can be performed in serum-free conditions both in the presence or absence of DMSO., Group: Patented cell line.
Proper citation: RRID:CVCL_XI49 Copy
https://web.expasy.org/cellosaurus/CVCL_B6AB
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Proper citation: RRID:CVCL_B6AB Copy
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