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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_0328
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Proper citation: BCRJ Cat# 0102, RRID:CVCL_0328 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_9720
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Miscellaneous: This cell line is exclusively produced and controlled by Biopredic International and owned by Inserm. BioPredic sells undifferentiated cell line (HPR101) that can be expanded, passaged, and frozen in-house to prepare a cell bank and differentiated ready-to-use cells, HPR116 (Cellosaurus=CVCL_WL73) that can be used immediately or in a few days after thawing, as a single-use disposable product (Biopredic)., Anecdotal: The 'RG' in the cell name stands for 'Rumin' and 'Gripon', the two scientists that were influential in the establishment of this cell line., Characteristics: Cell line main applications are sugar and lipid metabolism, physiopathology; drug metabolism and toxicology and viral infection., Characteristics: Can be induced to differentiate into hepatocyte-like cells by exposure to DMSO., Group: Patented cell line.
Proper citation: Millipore Cat# C103485, RRID:CVCL_9720 Copy
Misidentified Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4226
Organism: Anguilla japonica (Japanese eel)
Category: Spontaneously immortalized cell line
Comments: Problematic cell line: Misidentified. Originally thought to be of tilapia origin (Oreochromis niloticus) but found to be from eel (DOI=10.1007/s12562-018-1215-4; RCB). Is probably identical to Hepa-E1.., Group: Fish cell line.
Proper citation: ECACC Cat# 99072813, RRID:CVCL_4226 Copy
https://web.expasy.org/cellosaurus/CVCL_0328
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Proper citation: BCRC Cat# 60104, RRID:CVCL_0328 Copy
https://web.expasy.org/cellosaurus/CVCL_0327
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Secretes several liver products including albumin, alpha-fetoprotein, alpha 1-antitrypin and amylase (ECACC=92110305).
Proper citation: NCBI_Iran Cat# C517, RRID:CVCL_0327 Copy
https://web.expasy.org/cellosaurus/CVCL_0328
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Proper citation: KCLB Cat# 22026, RRID:CVCL_0328 Copy
https://web.expasy.org/cellosaurus/CVCL_0327
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Secretes several liver products including albumin, alpha-fetoprotein, alpha 1-antitrypin and amylase (ECACC=92110305).
Proper citation: ATCC Cat# CRL-1830, RRID:CVCL_0327 Copy
Misidentified Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4226
Organism: Anguilla japonica (Japanese eel)
Category: Spontaneously immortalized cell line
Comments: Problematic cell line: Misidentified. Originally thought to be of tilapia origin (Oreochromis niloticus) but found to be from eel (DOI=10.1007/s12562-018-1215-4; RCB). Is probably identical to Hepa-E1.., Group: Fish cell line.
Proper citation: RRID:CVCL_4226 Copy
Misidentified Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4226
Organism: Anguilla japonica (Japanese eel)
Category: Spontaneously immortalized cell line
Comments: Problematic cell line: Misidentified. Originally thought to be of tilapia origin (Oreochromis niloticus) but found to be from eel (DOI=10.1007/s12562-018-1215-4; RCB). Is probably identical to Hepa-E1.., Group: Fish cell line.
Proper citation: RCB Cat# RCB1156, RRID:CVCL_4226 Copy
https://web.expasy.org/cellosaurus/CVCL_RA18
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Reporter cell line, transduced with the LV-eGFP-PGKp-Puro vector encoding for eGFP under control of the spleen focus-forming virus (SFFV) promoter and the PuroR gene under the control of the mouse PGK promoter (Imanis=CL128).
Proper citation: RRID:CVCL_RA18 Copy
https://web.expasy.org/cellosaurus/CVCL_0327
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Secretes several liver products including albumin, alpha-fetoprotein, alpha 1-antitrypin and amylase (ECACC=92110305).
Proper citation: BCRC Cat# 60051, RRID:CVCL_0327 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_9720
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Miscellaneous: This cell line is exclusively produced and controlled by Biopredic International and owned by Inserm. BioPredic sells undifferentiated cell line (HPR101) that can be expanded, passaged, and frozen in-house to prepare a cell bank and differentiated ready-to-use cells, HPR116 (Cellosaurus=CVCL_WL73) that can be used immediately or in a few days after thawing, as a single-use disposable product (Biopredic)., Anecdotal: The 'RG' in the cell name stands for 'Rumin' and 'Gripon', the two scientists that were influential in the establishment of this cell line., Characteristics: Cell line main applications are sugar and lipid metabolism, physiopathology; drug metabolism and toxicology and viral infection., Characteristics: Can be induced to differentiate into hepatocyte-like cells by exposure to DMSO., Group: Patented cell line.
Proper citation: RRID:CVCL_9720 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_M177
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Virology: Inducibly expresses a hepatitis B virus (HBV) genome under the control of a tet operator/CMV promoter. Upon removal of tetracycline the cell line produces viral RNA and secrete virus-like particles into the supernatant., Biotechnology: Used in a bioassay that permits the large-scale screening of compound libraries for inhibitors of HBV replication., Population: Caucasian., Group: Patented cell line.
Proper citation: RRID:CVCL_M177 Copy
https://web.expasy.org/cellosaurus/CVCL_B6AS
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Proper citation: RRID:CVCL_B6AS Copy
https://web.expasy.org/cellosaurus/CVCL_A8BS
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Characteristics: Stably expresses two reporter genes: SEAP (secreted ALPP) and the Lucia luciferase. In this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB binding sites and 3 c-Rel binding sites. The Lucia luciferase reporter gene is under the control of an ISG54 minimal promoter in conjunction with 5 IFN-stimulated response elements (ISRE) (InvivoGen=hepg2d-nfis)., Population: Caucasian.
Proper citation: RRID:CVCL_A8BS Copy
https://web.expasy.org/cellosaurus/CVCL_VS10
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: African American.
Proper citation: RRID:CVCL_VS10 Copy
https://web.expasy.org/cellosaurus/CVCL_G003
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Karyotypic information: Near tetraploid karyotype (PubMed=8606490)., Characteristics: Tumorigenic. Injection into nude mice gives rise to subcutaneous tumors (PubMed=8606490).
Proper citation: RRID:CVCL_G003 Copy
https://web.expasy.org/cellosaurus/CVCL_VS06
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Proper citation: RRID:CVCL_VS06 Copy
https://web.expasy.org/cellosaurus/CVCL_KT01
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Characteristics: Transfected with an advanced reverse tetracycline-controlled transactivator (rtTA2(S)-M2), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16., Population: Caucasian.
Proper citation: RRID:CVCL_KT01 Copy
https://web.expasy.org/cellosaurus/CVCL_VS20
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Proper citation: RRID:CVCL_VS20 Copy
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