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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_5719
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: CLS Cat# 400391, RRID:CVCL_5719 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0229
Organism: Chlorocebus aethiops (Green monkey)
Category: Finite cell line
Comments: Virology: Susceptible to infection by SARS coronavirus (SARS-CoV) (PubMed=16494729)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Non-human primate cell line.
Proper citation: CLS Cat# 601470, RRID:CVCL_0229 Copy
Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_2898
Organism: Bos taurus (Bovine)
Category: Finite cell line
Comments: Virology: Persistently infected by bovine viral diarrhea virus (BVDV) (PubMed=7989438)., Characteristics: Susceptible to infection by Ehrlichia ruminantium (CelloPub=CLPUB00632)., Characteristics: FGF dependent.
Proper citation: CLS Cat# 302159, RRID:CVCL_2898 Copy
https://web.expasy.org/cellosaurus/CVCL_6974
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Discontinued: Thermo Fisher/Invitrogen; Catalog number R620-07., Characteristics: The use of recombinant protein expression vectors containing the EBV oriP in cell lines stably expressing EBV's EBNA1 protein significantly increases recombinant protein yield.
Proper citation: CLS Cat# 300264, RRID:CVCL_6974 Copy
https://web.expasy.org/cellosaurus/CVCL_B288
Organism: Mus musculus (Mouse)
Disease: Mouse colon adenocarcinoma
Category: Cancer cell line
Comments: Caution: The authors of PubMed=25434994 indicate that they have sequenced the mitochondrial genome of the 'rat' cell line MCA38. Their submitted DNA sequence (KM820832.1) is indeed a rat sequence but is labelled as originating from 'rat isolate 406'., Miscellaneous: Comparative analysis of MC38 cells obtained from Kerafast (MC38-K) and from Leiden University Medical Center (MC38-L) shows major differences in term of mutations and mRNA expression (PubMed=36969213).
Proper citation: CLS Cat# 305223, RRID:CVCL_B288 Copy
https://web.expasy.org/cellosaurus/CVCL_3855
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: CLS Cat# 300487, RRID:CVCL_3855 Copy
https://web.expasy.org/cellosaurus/CVCL_5J48
Organism: Mus musculus (Mouse)
Disease: Mouse gastric carcinoma
Category: Cancer cell line
Proper citation: CLS Cat# 300652, RRID:CVCL_5J48 Copy
https://web.expasy.org/cellosaurus/CVCL_B063
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: CLS Cat# 305182, RRID:CVCL_B063 Copy
https://web.expasy.org/cellosaurus/CVCL_2665
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Anecdotal: OKT3 was the first monoclonal antibody to be approved for clinical use in humans., Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized teplizumab (MGA031) therapeutic antibody., Biotechnology: The monoclonal antibody produced by this hybridoma was used as an immunosuppressant drug under the name Muromonab-CD3 (Orthoclone OKT3)., Group: Patented cell line.
Proper citation: CLS Cat# 300499, RRID:CVCL_2665 Copy
https://web.expasy.org/cellosaurus/CVCL_2664
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: CLS Cat# 300500, RRID:CVCL_2664 Copy
https://web.expasy.org/cellosaurus/CVCL_5845
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: CLS Cat# 400100, RRID:CVCL_5845 Copy
https://web.expasy.org/cellosaurus/CVCL_D899
Organism: Mus musculus (Mouse)
Category: Conditionally immortalized cell line
Comments: Characteristics: Growth at the permissive (33 Celsius) temperature results in dedifferentiation of the cells and accelerated proliferation. At the restrictive temperature (39 Celsius) cell proliferation halts in about 48h.
Proper citation: CLS Cat# 305548, RRID:CVCL_D899 Copy
https://web.expasy.org/cellosaurus/CVCL_4511
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: CLS Cat# 305354, RRID:CVCL_4511 Copy
https://web.expasy.org/cellosaurus/CVCL_8786
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: CLS Cat# 305261, RRID:CVCL_8786 Copy
https://web.expasy.org/cellosaurus/CVCL_6898
Organism: Homo sapiens (Human)
Disease: Esophageal squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Chinese., Problematic cell line: Partially contaminated. Some stocks of this cell line are contaminated with HeLa (ICLAC)..
Proper citation: CLS Cat# 305511, RRID:CVCL_6898 Copy
https://web.expasy.org/cellosaurus/CVCL_3285
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Donor information: Established from foreskin pooled from two individuals (ATCC=SCRC-1041).
Proper citation: CLS Cat# 305790, RRID:CVCL_3285 Copy
https://web.expasy.org/cellosaurus/CVCL_0281
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Comments: Characteristics: Exhibits high levels of Gnrh1 expression and secretes GnRH in response to depolarization.
Proper citation: CLS Cat# 305779, RRID:CVCL_0281 Copy
https://web.expasy.org/cellosaurus/CVCL_C261
Organism: Mus musculus (Mouse)
Category: Embryonic stem cell
Comments: Karyotypic information: Mosaic; 42,XY,+Y,+8; 41,XY,+Y; 40,XY (PubMed=23320952).
Proper citation: CLS Cat# 305738, RRID:CVCL_C261 Copy
https://web.expasy.org/cellosaurus/CVCL_S979
Organism: Homo sapiens (Human)
Disease: Lung papillary adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese., From: Immuno-Biological Laboratories (IBL); Tokyo; Japan.
Proper citation: CLS Cat# 500311, RRID:CVCL_S979 Copy
https://web.expasy.org/cellosaurus/CVCL_3940
Organism: Mus musculus (Mouse)
Disease: Mouse multiple myeloma
Category: Cancer cell line
Comments: Characteristics: Lacks endogenous glutamine synthetase (GS) activity., Characteristics: Commonly employed for monoclonal antibody expression., Group: Hybridoma fusion partner cell line.
Proper citation: CLS Cat# 400109, RRID:CVCL_3940 Copy
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