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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0030
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: HeLa is the most frequent contributor to cell lines contamination., Anecdotal: Was flown since the 1960s on at least ten different space missions: Korabl-Sputnik-2, Vostok-1, Vostok-4, Vostok-5 and Vostok-6, Voshkod 1 and Zond-5, Discoverer XVIII, Progress M-35/Mir and Shuttle STS-89., Anecdotal: The HeLa cell line and its story inspired Australian artist Cynthia Verspaget to embark in 2003 on a artistic project 'The Anarchy Cell Line' (TAnCL) where she mixed her blood with HeLa cells. This work later spawned a PhD thesis (CelloPub=CLPUB00376) where among other things she makes the observation that two main taxonomical distinctions present in the zombie, living/dead and human/nonhuman, are also present in the HeLa cell line., Anecdotal: The fascinating story of the HeLa cell line and of Henrietta Lacks from whom these cells originate are described in the book of Rebecca Skloot (CelloPub=CLPUB00377)., Anecdotal: The HeLa cell line which was established in February 1951 is the oldest human immortal cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: HeLa has 5 five HPV18 integration sites: three on normal chromosomes 8 at 8q24 and two on derivative chromosomes, der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22) (q24;q13)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Proper citation: ATCC Cat# CCL-2, RRID:CVCL_0030 Copy
https://web.expasy.org/cellosaurus/CVCL_B053
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Transfected with a recombinant adeno-associated virus type 2 (rAAV) (PubMed=10953917)., Population: African American., Group: Adeno-associated virus packaging cell line.
Proper citation: ATCC Cat# CRL-2972, RRID:CVCL_B053 Copy
https://web.expasy.org/cellosaurus/CVCL_1278
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Group: Serum/protein free medium cell line.
Proper citation: ATCC Cat# CCL-2.3, RRID:CVCL_1278 Copy
Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_1906
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Population: African American., Part of: KuDOS 95 cell line panel., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=20143388). Originally thought to originate from a 56 year old male patient with a laryngeal carcinoma..
Proper citation: ATCC Cat# CCL-23, RRID:CVCL_1906 Copy
Misclassified Discontinued
https://web.expasy.org/cellosaurus/CVCL_B367
Organism: Homo sapiens (Human)
Disease: Adult T lymphoblastic lymphoma
Category: Cancer cell line
Comments: Problematic cell line: Misclassified. Originally thought to be a Hodgkin lymphoma cell line, but seems to be a T lymphoblastic lymphoma (PubMed=29533902)..
Proper citation: ATCC Cat# CRL-2626, RRID:CVCL_B367 Copy
https://web.expasy.org/cellosaurus/CVCL_9179
Organism: Mus musculus (Mouse)
Category: Hybridoma
Proper citation: ATCC Cat# HB-252, RRID:CVCL_9179 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3698
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: ATCC Cat# CRL-7717, RRID:CVCL_3698 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3699
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: ATCC Cat# CRL-7718, RRID:CVCL_3699 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_U777
Organism: Homo sapiens (Human)
Disease: Marfan syndrome
Category: Finite cell line
Proper citation: ATCC Cat# CRL-1174, RRID:CVCL_U777 Copy
https://web.expasy.org/cellosaurus/CVCL_4W07
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: Adapted to growth in suspension (ATCC=CRL-1573.3).
Proper citation: ATCC Cat# CRL-1573.3, RRID:CVCL_4W07 Copy
https://web.expasy.org/cellosaurus/CVCL_J013
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: ATCC Cat# HB-8554, RRID:CVCL_J013 Copy
https://web.expasy.org/cellosaurus/CVCL_4234
Organism: Mus musculus (Mouse)
Disease: Mouse thymic lymphoma
Category: Cancer cell line
Comments: Characteristics: Resistant to X-rays, but sensitive to ultraviolet radiation.
Proper citation: ATCC Cat# CRL-1722, RRID:CVCL_4234 Copy
https://web.expasy.org/cellosaurus/CVCL_6414
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: ATCC Cat# CRL-10998, RRID:CVCL_6414 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_U239
Organism: Leontopithecus rosalia (Golden lion tamarin)
Category: Finite cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Non-human primate cell line.
Proper citation: ATCC Cat# CRL-6307, RRID:CVCL_U239 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4536
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: ATCC Cat# CRL-2648, RRID:CVCL_4536 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4536
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: ATCC Cat# CCL-1.3, RRID:CVCL_4536 Copy
https://web.expasy.org/cellosaurus/CVCL_4532
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: ATCC Cat# HB-8705, RRID:CVCL_4532 Copy
https://web.expasy.org/cellosaurus/CVCL_J015
Organism: Mus musculus (Mouse)
Category: Hybridoma
Proper citation: ATCC Cat# HB-171, RRID:CVCL_J015 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_6665
Organism: Mus musculus (Mouse)
Disease: Mouse thymic lymphoma
Category: Cancer cell line
Comments: Biotechnology: Used for mutation assays to predict the carcinogenic potential of chemicals. Allows the quantitation of forward mutations at the thymidine kinase (TK) locus. These TK heterozygous cells are treated with a range of doses of the test substance. The cells are incubated, washed free of tests substance and allowed time for the phenotypic expression of newly induced mutations (PubMed=1093012; PubMed=3416837; PubMed=4360720; PubMed=7329431).
Proper citation: ATCC Cat# CRL-9518, RRID:CVCL_6665 Copy
https://web.expasy.org/cellosaurus/CVCL_0385
Organism: Rattus norvegicus (Rat)
Category: Transformed cell line
Comments: Anecdotal: Called L6 by David Yaffe because he and Sara Neuman established the cell line during the Six-Day war in 1967 (PubMed=33117511).
Proper citation: ATCC Cat# CRL-1458, RRID:CVCL_0385 Copy
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