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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_L280
Organism: Homo sapiens (Human)
Disease: Testicular teratoma
Category: Cancer cell line
Comments: Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-747, RRID:CVCL_L280 Copy
https://web.expasy.org/cellosaurus/CVCL_2211
Organism: Homo sapiens (Human)
Category: Hybrid cell line
Proper citation: DSMZ Cat# ACC-598, RRID:CVCL_2211 Copy
https://web.expasy.org/cellosaurus/CVCL_1920
Organism: Oncorhynchus mykiss (Rainbow trout)
Category: Spontaneously immortalized cell line
Comments: Anecdotal: First fish cell line, established in 1962., Group: Fish cell line.
Proper citation: DSMZ Cat# ACC-352, RRID:CVCL_1920 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: DSMZ Cat# ACC-125, RRID:CVCL_0549 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_1680
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from an urinary bladder carcinoma..
Proper citation: DSMZ Cat# ACC-229, RRID:CVCL_1680 Copy
https://web.expasy.org/cellosaurus/CVCL_2179
Organism: Mus musculus (Mouse)
Disease: Mouse leukemia
Category: Cancer cell line
Proper citation: DSMZ Cat# ACC-415, RRID:CVCL_2179 Copy
https://web.expasy.org/cellosaurus/CVCL_2178
Organism: Rattus norvegicus (Rat)
Category: Spontaneously immortalized cell line
Proper citation: DSMZ Cat# ACC-332, RRID:CVCL_2178 Copy
https://web.expasy.org/cellosaurus/CVCL_2181
Organism: Mus musculus (Mouse)
Disease: Mouse erythroid leukemia
Category: Cancer cell line
Proper citation: DSMZ Cat# ACC-391, RRID:CVCL_2181 Copy
https://web.expasy.org/cellosaurus/CVCL_2159
Organism: Mus musculus (Mouse)
Category: Factor-dependent cell line
Comments: Characteristics: IL7 dependent.
Proper citation: DSMZ Cat# ACC-241, RRID:CVCL_2159 Copy
https://web.expasy.org/cellosaurus/CVCL_2H32
Organism: Homo sapiens (Human)
Disease: Chronic lymphocytic leukemia
Category: Transformed cell line
Proper citation: DSMZ Cat# ACC-794, RRID:CVCL_2H32 Copy
https://web.expasy.org/cellosaurus/CVCL_2188
Organism: Mus musculus (Mouse)
Disease: Mouse osteosarcoma
Category: Cancer cell line
Comments: Karyotypic information: Near diploid karyotype. Has lost chromosome Y (PubMed=39662063).
Proper citation: DSMZ Cat# ACC-523, RRID:CVCL_2188 Copy
https://web.expasy.org/cellosaurus/CVCL_2074
Organism: Spodoptera frugiperda (Fall armyworm)
Category: Spontaneously immortalized cell line
Comments: Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: DSMZ Cat# ACC-292, RRID:CVCL_2074 Copy
https://web.expasy.org/cellosaurus/CVCL_1901
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: DSMZ Cat# ACC-652, RRID:CVCL_1901 Copy
https://web.expasy.org/cellosaurus/CVCL_1900
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: DSMZ Cat# ACC-651, RRID:CVCL_1900 Copy
https://web.expasy.org/cellosaurus/CVCL_1899
Organism: Homo sapiens (Human)
Disease: Tongue squamous cell carcinoma
Category: Cancer cell line
Comments: Virology: Contains from 100 to 500 copies of the HPV16 genome (PubMed=24201445)., Population: Caucasian., Part of: OPC-22 oral and pharyngeal cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-670, RRID:CVCL_1899 Copy
https://web.expasy.org/cellosaurus/CVCL_2229
Organism: Homo sapiens (Human)
Disease: Floor of mouth squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-668, RRID:CVCL_2229 Copy
https://web.expasy.org/cellosaurus/CVCL_1819
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma
Category: Cancer cell line
Comments: Miscellaneous: Originally assigned to be from a B-cell acute lymphoblastic leukemia., Population: Caucasian., Part of: MD Anderson Cell Lines Project., Part of: LL-100 blood cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-586, RRID:CVCL_1819 Copy
https://web.expasy.org/cellosaurus/CVCL_1912
Organism: Chlorocebus sabaeus (Green monkey)
Category: Spontaneously immortalized cell line
Comments: Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=34339474)., Virology: Susceptible to infection by Middle East respiratory syndrome-related coronavirus (MERS-CoV) (PubMed=25531820)., Group: Vaccine production cell line., Group: Non-human primate cell line.
Proper citation: DSMZ Cat# ACC-33, RRID:CVCL_1912 Copy
https://web.expasy.org/cellosaurus/CVCL_S503
Organism: Rousettus aegyptiacus (Egyptian rousette)
Category: Transformed cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Group: Bat cell line.
Proper citation: DSMZ Cat# ACC-754, RRID:CVCL_S503 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_S504
Organism: Rousettus aegyptiacus (Egyptian rousette)
Category: Transformed cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., From: ProBioGen AG; Berlin; Germany., Problematic cell line: Partially contaminated. Some cultures of R06E are contaminated with the Vero cell line (PubMed=22754654), this is the case of the culture used in PubMed=20808767.., Group: Patented cell line., Group: Bat cell line.
Proper citation: DSMZ Cat# ACC-756, RRID:CVCL_S504 Copy
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