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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_C6NQ
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: Responds to activation of the canonical Wnt signaling pathway by increasing expression of firefly luciferase. Luciferase reporter gene expression is under the control of a promoter with 7 LEF/TCF binding sites (from parent cell line HEK 293 STF)., Characteristics: Stably express high levels of murine Wnt3a (PubMed=19022675).
Proper citation: RRID:CVCL_C6NQ Copy
https://web.expasy.org/cellosaurus/CVCL_C8V2
Organism: Homo sapiens (Human)
Disease: Adult hepatocellular carcinoma
Category: Cancer cell line
Comments: Population: Korean.
Proper citation: RRID:CVCL_C8V2 Copy
https://web.expasy.org/cellosaurus/CVCL_C8WG
Organism: Homo sapiens (Human)
Disease: Childhood acute monocytic leukemia
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_C8WG Copy
https://web.expasy.org/cellosaurus/CVCL_C8WM
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Population: Caucasian., Problematic cell line: Misidentified. Parent cell line (U-87MG ATCC) is not the original glioblastoma cell line established in 1968 at the University of Uppsala..
Proper citation: RRID:CVCL_C8WM Copy
https://web.expasy.org/cellosaurus/CVCL_C7NK
Organism: Chlorocebus sabaeus (Green monkey)
Category: Spontaneously immortalized cell line
Comments: Characteristics: Transfected with a PuroR-P2A-TMPRSS2-T2A-ACE2 plasmid under the control of a CAG promoter (BEI_Resources=NR-54970)., Group: SARS-CoV-2 research cell line., Group: Non-human primate cell line.
Proper citation: RRID:CVCL_C7NK Copy
https://web.expasy.org/cellosaurus/CVCL_D0PU
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: From: Vrije Universiteit Amsterdam; Amsterdam; Netherlands.
Proper citation: RRID:CVCL_D0PU Copy
https://web.expasy.org/cellosaurus/CVCL_D0PT
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: From: Vrije Universiteit Amsterdam; Amsterdam; Netherlands.
Proper citation: RRID:CVCL_D0PT Copy
https://web.expasy.org/cellosaurus/CVCL_C7HE
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: Characteristics: Using CRISPR/Cas9 GFP under the control of a CAG promoter has been inserted at the AAVS1 safe harbor locus.
Proper citation: RRID:CVCL_C7HE Copy
https://web.expasy.org/cellosaurus/CVCL_C7IM
Organism: Homo sapiens (Human)
Disease: Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_C7IM Copy
https://web.expasy.org/cellosaurus/CVCL_C7XH
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: From: Cell Applications, Inc.; San Diego; USA.
Proper citation: RRID:CVCL_C7XH Copy
https://web.expasy.org/cellosaurus/CVCL_C7PL
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: RRID:CVCL_C7PL Copy
https://web.expasy.org/cellosaurus/CVCL_C8W9
Organism: Homo sapiens (Human)
Disease: Breast adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Group: Triple negative breast cancer (TNBC) cell line.
Proper citation: RRID:CVCL_C8W9 Copy
https://web.expasy.org/cellosaurus/CVCL_C3LZ
Organism: Homo sapiens (Human)
Disease: Esophageal squamous cell carcinoma
Category: Cancer cell line
Comments: Characteristics: Radioresistant. Was irradiated at 1 Gy three times, at 2 Gy three times and 4 Gy three times (PubMed=36090890)., Population: Japanese.
Proper citation: RRID:CVCL_C3LZ Copy
https://web.expasy.org/cellosaurus/CVCL_C5VB
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Comments: Miscellaneous: Cell line information from personal communication of Gamage, Akshamal Mihiranga., Characteristics: Readily divide in CSF-1 free-RPMI media and are to be passaged on non-tissue culture treated plastic ware (Direct_author_submission).
Proper citation: RRID:CVCL_C5VB Copy
https://web.expasy.org/cellosaurus/CVCL_C4PL
Organism: Mus musculus (Mouse)
Disease: Mouse gastric neuroendocrine neoplasm
Category: Cancer cell line
Comments: Characteristics: Secretes substantial amount of ghrelin.
Proper citation: RRID:CVCL_C4PL Copy
https://web.expasy.org/cellosaurus/CVCL_C6JY
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Proper citation: RRID:CVCL_C6JY Copy
https://web.expasy.org/cellosaurus/CVCL_C4UU
Organism: Felis catus (Cat)
Disease: Feline oral squamous cell carcinoma
Category: Cancer cell line
Proper citation: RRID:CVCL_C4UU Copy
https://web.expasy.org/cellosaurus/CVCL_C4UV
Organism: Felis catus (Cat)
Disease: Feline oral squamous cell carcinoma
Category: Cancer cell line
Comments: Karyotypic information: Half of the cells are diploid and the remaining are tetraploid (PubMed=22265717).
Proper citation: RRID:CVCL_C4UV Copy
https://web.expasy.org/cellosaurus/CVCL_2758
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Population: Caucasian; Swedish.
Proper citation: ATCC Cat# CCL-95.1, RRID:CVCL_2758 Copy
Discontinued Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0579
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Anecdotal: Have been flown in space on Skylab-3 to study growth in microgravity (PubMed=352912)., Anecdotal: Leonard Hayflick when numbering diploid cell strains 'jumped' directly from WI-27 (which failed) to WI-38 (CelloPub=CLPUB00391)., Senescence: Life expectancy of 50 +- 10 population doublings. Senesces at 38 PDL (PubMed=17395773)., Characteristics: Used in many context such as senescence and aging studies., Biotechnology: Was used in the early 1970's for the production of the Human Diploid Cell Vaccine (HDCV) vaccine against rabies by Institut Merieux., Biotechnology: Used for the production of live oral adenovirus type 4 and type 7 vaccine used by the US military. Produced first by Wyeth Laboratories from 1971 to 1999 and from 2011 onward by Barr Pharmaceuticals., Biotechnology: Used for the production of RA27/3 - the first rubella virus vaccine., Population: Caucasian; Swedish., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut).
Proper citation: Coriell Cat# AG06814-M, RRID:CVCL_0579 Copy
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