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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
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https://web.expasy.org/cellosaurus/CVCL_0514
Organism: Potorous tridactylus (Potoroo)
Category: Spontaneously immortalized cell line
Comments: Karyotypic information: As the diploid chromosome number of P.tridactylus is quite small (2n=12), this cell line is suited to the study of mitosis and to easily visualize the chromosomes under a microscope., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Marsupial cell line.
Proper citation: CLS Cat# 608316, RRID:CVCL_0514 Copy
https://web.expasy.org/cellosaurus/CVCL_B7QI
Organism: Siganus canaliculatus (White-spotted spinefoot)
Category: Spontaneously immortalized cell line
Comments: Group: Fish cell line.
Proper citation: RRID:CVCL_B7QI Copy
https://web.expasy.org/cellosaurus/CVCL_B7NI
Organism: Acipenser fulvescens (Lake sturgeon)
Category: Spontaneously immortalized cell line
Comments: Group: Fish cell line.
Proper citation: RRID:CVCL_B7NI Copy
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https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: CLS Cat# 604328, RRID:CVCL_0549 Copy
https://web.expasy.org/cellosaurus/CVCL_B7N1
Organism: Gasterosteus aculeatus (Three-spined stickleback)
Category: Spontaneously immortalized cell line
Comments: Group: Fish cell line.
Proper citation: RRID:CVCL_B7N1 Copy
https://web.expasy.org/cellosaurus/CVCL_B7RV
Organism: Carassius auratus (Goldfish)
Category: Spontaneously immortalized cell line
Comments: Characteristics: Adapted to growth at 37 Celsius., Group: Fish cell line.
Proper citation: RRID:CVCL_B7RV Copy
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https://web.expasy.org/cellosaurus/CVCL_0059
Organism: Chlorocebus sabaeus (Green monkey)
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank=DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603)., Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank=DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain., Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia)., Biotechnology: Used for the production of the live smallpox (vaccinia) vaccine (Trade name: ACAM2000)., Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix)., Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV)., Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB)., Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio)., Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Non-human primate cell line.
Proper citation: CLS Cat# 605372, RRID:CVCL_0059 Copy
https://web.expasy.org/cellosaurus/CVCL_B7QJ
Organism: Notophthalmus viridescens (Eastern newt)
Category: Spontaneously immortalized cell line
Comments: Group: Amphibian cell line.
Proper citation: RRID:CVCL_B7QJ Copy
https://web.expasy.org/cellosaurus/CVCL_B7RC
Organism: Notophthalmus viridescens (Eastern newt)
Category: Spontaneously immortalized cell line
Comments: Group: Amphibian cell line.
Proper citation: RRID:CVCL_B7RC Copy
https://web.expasy.org/cellosaurus/CVCL_B7QH
Organism: Oreochromis spilurus (Sabaki tilapia)
Category: Spontaneously immortalized cell line
Comments: Characteristics: Optimal growth at 28 Celsius (DOI=10.1111/j.1095-8649.1987.tb05322.x)., Group: Fish cell line.
Proper citation: RRID:CVCL_B7QH Copy
https://web.expasy.org/cellosaurus/CVCL_B7DX
Organism: Chlorocebus sabaeus (Green monkey)
Category: Spontaneously immortalized cell line
Comments: Characteristics: Adapted to the serum free, chemically-defined culture medium SciN4Vero (CLS=605372-CDM)., Group: Vaccine production cell line., Group: Serum/protein free medium cell line., Group: Non-human primate cell line.
Proper citation: CLS Cat# 605372-CDM, RRID:CVCL_B7DX Copy
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https://web.expasy.org/cellosaurus/CVCL_6369
Organism: Mesocricetus auratus (Golden hamster)
Category: Spontaneously immortalized cell line
Comments: Group: Patented cell line.
Proper citation: ATCC Cat# CRL-13001, RRID:CVCL_6369 Copy
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https://web.expasy.org/cellosaurus/CVCL_1914
Organism: Mesocricetus auratus (Golden hamster)
Category: Spontaneously immortalized cell line
Comments: Miscellaneous: Not distributed parent cell line., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Space-flown cell line (cellonaut).
Proper citation: Ubigene Cat# YC-A049, RRID:CVCL_1914 Copy
https://web.expasy.org/cellosaurus/CVCL_UR37
Organism: Mesocricetus auratus (Golden hamster)
Category: Spontaneously immortalized cell line
Proper citation: ATCC Cat# CRL-3423, RRID:CVCL_UR37 Copy
https://web.expasy.org/cellosaurus/CVCL_RW96
Organism: Mesocricetus auratus (Golden hamster)
Category: Spontaneously immortalized cell line
Comments: Caution: This cell line is protected by IP rights of the inventors. The CCLV of the Friedrich-Loeffler-Institute, Federal Research Center for Virus Diseases of Animals is the sole approved distributor is CCLV (personal communication of Finke, Stefan)., Characteristics: Expression of the T7 RNA polymerase gene is under control of the cytomegalovirus promoter (PubMed=9847328).
Proper citation: CCLV Cat# CCLV-RIE 0583, RRID:CVCL_RW96 Copy
https://web.expasy.org/cellosaurus/CVCL_Z090
Organism: Bombyx mori (Silk moth)
Category: Spontaneously immortalized cell line
Comments: Characteristics: Used in a transient luciferase assay system for measuring extrachromosomal homologous recombination (HR). Expresses a disrupted luciferase gene which can become enzymatically active through HR (PubMed=14680819)., Group: Insect cell line.
Proper citation: RCB Cat# RCB2126, RRID:CVCL_Z090 Copy
https://web.expasy.org/cellosaurus/CVCL_D5GM
Organism: Nicotiana tabacum (Common tobacco)
Category: Spontaneously immortalized cell line
Comments: Anecdotal: This cell line was generated at the Japan Tobacco and Salt Monopoly Public Corporation. In 1982 Toshiyuki Nagata brought it with him to the USA and left it there after renaming it to NT-1 in order to distribute it clandestinely because he was not allowed officially to give the BY-2 cell line to others. He called it NT-1 as it could both mean Nicotiana tabacum or Nagata, Toshiyuki (PubMed=37642778)., Characteristics: Used as model for the electrochemical sensing of beta-glucuronidase activity of transgenic cell lines (PubMed=29982119)., Characteristics: Tested for the production of viral proteins (PubMed=14680934; PubMed=12601177; PubMed=16187337)., Characteristics: Tested for the production of synthetic proteins (PubMed=15818563)., Characteristics: Tested for the production of bacterial proteins (PubMed=14688094; PubMed=22928883)., Characteristics: Tested for the production of animal proteins (PubMed=7766897)., Characteristics: Produces low levels of nicotine (PubMed=18567891)., Characteristics: Can be used to prepare protoplasts (PubMed=17947977)., Group: Plant cell line.
Proper citation: DSMZ Cat# PC-1181, RRID:CVCL_D5GM Copy
https://web.expasy.org/cellosaurus/CVCL_0188
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Comments: Characteristics: Capable, upon starvation, of differentiating into contractile myotubes that express muscle-specific proteins., Part of: ENCODE project mouse cell lines.
Proper citation: Ubigene Cat# YC-A010, RRID:CVCL_0188 Copy
https://web.expasy.org/cellosaurus/CVCL_6581
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: ATCC Cat# CRL-2581, RRID:CVCL_6581 Copy
https://web.expasy.org/cellosaurus/CVCL_0F01
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: ATCC Cat# CRL-2582, RRID:CVCL_0F01 Copy
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