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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
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https://web.expasy.org/cellosaurus/CVCL_0421
Organism: Bos taurus (Bovine)
Category: Spontaneously immortalized cell line
Comments: Virology: Not susceptible to infection by wild-type and vaccinal strains of myxoma virus (MYXV) (PubMed=17900332)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: CLS Cat# 600396, RRID:CVCL_0421 Copy
https://web.expasy.org/cellosaurus/CVCL_B7HR
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Comments: Miscellaneous: Sex of mouse and STR profile from personal communication of Hummler, Edith., Miscellaneous: Doubling time from personal communication of Rossier, Bernard Claude., Characteristics: Expresses epithelial sodium channels (ENaC) as well as the necessary cellular machinery to enable their stimulation by physiological concentrations of aldosterone, including 11-betahydroxysteroid dehydrogenase (HSD11b2), mineralocorticoid and glucocorticoid receptors and have therefore been used as a model for the study of principal cells physiology (PubMed=15743993; PubMed=29357433).
Proper citation: RRID:CVCL_B7HR Copy
https://web.expasy.org/cellosaurus/CVCL_4624
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: CancerTools Cat# 153599, RRID:CVCL_4624 Copy
https://web.expasy.org/cellosaurus/CVCL_C0CU
Organism: Homo sapiens (Human)
Disease: Invasive breast carcinoma of no special type
Category: Cancer cell line
Comments: Miscellaneous: Doubling time, ABCB1 status and STR profile from personal communication of Daniel, Petr., Characteristics: Generated by step-increasing drug concentration to 300 nm of SB-T-0035. Overexpresses ABCB1 which is amplified and inserted in chromosome 19 (PubMed=29625142; Direct_author_submission)., Population: Caucasian.
Proper citation: RRID:CVCL_C0CU Copy
https://web.expasy.org/cellosaurus/CVCL_B7HR
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Comments: Miscellaneous: Sex of mouse and STR profile from personal communication of Hummler, Edith., Miscellaneous: Doubling time from personal communication of Rossier, Bernard Claude., Characteristics: Expresses epithelial sodium channels (ENaC) as well as the necessary cellular machinery to enable their stimulation by physiological concentrations of aldosterone, including 11-betahydroxysteroid dehydrogenase (HSD11b2), mineralocorticoid and glucocorticoid receptors and have therefore been used as a model for the study of principal cells physiology (PubMed=15743993; PubMed=29357433).
Proper citation: ABM Cat# T0620, RRID:CVCL_B7HR Copy
https://web.expasy.org/cellosaurus/CVCL_B7P7
Organism: Homo sapiens (Human)
Disease: Invasive breast carcinoma of no special type
Category: Cancer cell line
Comments: Miscellaneous: Doubling time, ABCB1 status and STR profile from personal communication of Daniel, Petr., Characteristics: Generated by step-increasing drug concentration to 300 nm of paclitaxel. Overexpresses ABCB1 which is amplified and inserted in chromosome 3 (PubMed=27664577; Direct_author_submission)., Population: Caucasian.
Proper citation: RRID:CVCL_B7P7 Copy
https://web.expasy.org/cellosaurus/CVCL_B7F7
Organism: Homo sapiens (Human)
Disease: Plasma cell myeloma
Category: Cancer cell line
Comments: Characteristics: Produces IgA lambda (from parent cell line MM1.S)., Population: African American.
Proper citation: RRID:CVCL_B7F7 Copy
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https://web.expasy.org/cellosaurus/CVCL_0440
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Senescence: Capable of attaining 42-46 population doublings before the onset of senescence (ATCC=CCL-171). Senesces at 26 PDL (PubMed=17395773)., Biotechnology: Used for the production of the live zoster vaccine (Trade name: Zostavax)., Biotechnology: Used for the production of the live varicella virus vaccine (Trade name: Varivax)., Biotechnology: Used for the production of the Hepatitis A vaccines Avaxim, Epaxal, Havrix and Vaqta., Biotechnology: Used for the production of the Human Diploid Cell Vaccine (HDCV) against rabies (Trade name: Imovax Rabies)., Group: Vaccine production cell line.
Proper citation: CLS Cat# 300395, RRID:CVCL_0440 Copy
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https://web.expasy.org/cellosaurus/CVCL_0594
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Comments: Miscellaneous: PubMed=23430347 has a different value for STR 6-4 (14.3) than that of NIST (15.3) due to a change in the marker motif (personal communication of Almeida, Jamie L.)., Miscellaneous: PubMed=23430347 has a different value for STR 4-2 (19.3) than that of NIST (19.3,20.3) due to a change in the stutter rules (personal communication of Almeida, Jamie L.)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: ENCODE project mouse cell lines.
Proper citation: CLS Cat# 400101, RRID:CVCL_0594 Copy
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https://web.expasy.org/cellosaurus/CVCL_0462
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Comments: Miscellaneous: PubMed=23430347 has a different value for STR 6-4 (16) than that of NIST (17,18) due to a change in the marker motif (personal communication of Almeida, Jamie L.)., Anecdotal: First established continuous cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Space-flown cell line (cellonaut).
Proper citation: CLS Cat# 400260, RRID:CVCL_0462 Copy
Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4032
Organism: Mus musculus (Mouse)
Disease: Mouse multiple myeloma
Category: Cancer cell line
Comments: Miscellaneous: PubMed=23430347 has a different value for STR 6-4 (17,18) than that of NIST (18,19) due to a change in the marker motif (personal communication of Almeida, Jamie L.)., Group: Hybridoma fusion partner cell line.
Proper citation: CLS Cat# 400118, RRID:CVCL_4032 Copy
https://web.expasy.org/cellosaurus/CVCL_2153
Organism: Mus musculus (Mouse)
Disease: Mouse teratocarcinoma
Category: Cancer cell line
Comments: Caution: There seem to be 3 distinct cell lines which were assigned NCBI_Iran catalog number C422.
Proper citation: CLS Cat# 400416, RRID:CVCL_2153 Copy
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https://web.expasy.org/cellosaurus/CVCL_0514
Organism: Potorous tridactylus (Potoroo)
Category: Spontaneously immortalized cell line
Comments: Karyotypic information: As the diploid chromosome number of P.tridactylus is quite small (2n=12), this cell line is suited to the study of mitosis and to easily visualize the chromosomes under a microscope., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Marsupial cell line.
Proper citation: CLS Cat# 608316, RRID:CVCL_0514 Copy
https://web.expasy.org/cellosaurus/CVCL_B7TK
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Proper citation: RRID:CVCL_B7TK Copy
https://web.expasy.org/cellosaurus/CVCL_B7SD
Organism: Mus musculus (Mouse)
Disease: Mouse lymphoma
Category: Cancer cell line
Comments: Characteristics: Overexpresses PU.1 (Spi1).
Proper citation: RRID:CVCL_B7SD Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_2710
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Population: Caucasian., Part of: Human variation panel., Part of: Genetic Testing Reference Material (GeT-RM) samples.
Proper citation: CLS Cat# 300318, RRID:CVCL_2710 Copy
https://web.expasy.org/cellosaurus/CVCL_6230
Organism: Homo sapiens (Human)
Disease: Rectal adenocarcinoma
Category: Cancer cell line
Comments: From: Scott and White Clinic; Temple; USA.
Proper citation: CLS Cat# 300351, RRID:CVCL_6230 Copy
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https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: CLS Cat# 604328, RRID:CVCL_0549 Copy
https://web.expasy.org/cellosaurus/CVCL_2199
Organism: Mus musculus (Mouse)
Disease: Mouse multiple myeloma
Category: Cancer cell line
Comments: Group: Hybridoma fusion partner cell line.
Proper citation: CLS Cat# 400481, RRID:CVCL_2199 Copy
https://web.expasy.org/cellosaurus/CVCL_6028
Organism: Homo sapiens (Human)
Disease: Melanoma
Category: Cancer cell line
Comments: From: Memorial Sloan Kettering Cancer Center; New York; USA.
Proper citation: CLS Cat# 300336, RRID:CVCL_6028 Copy
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