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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Contaminated
https://web.expasy.org/cellosaurus/CVCL_A8JP
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Parent cell line (HEp-2) has been shown to be a HeLa derivative..
Proper citation: RRID:CVCL_A8JP Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_RX05
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Expression of eGFP is under the control of the control of the mouse Mx2 promoter (PubMed=27346232)., Biotechnology: Used for a reporter gene assay (RGA) of the human type 1 interferon potency (PubMed=27346232)., Population: African American., Problematic cell line: Contaminated. Parent cell line (HEp-2) has been shown to be a HeLa derivative..
Proper citation: RRID:CVCL_RX05 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_9720
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Miscellaneous: This cell line is exclusively produced and controlled by Biopredic International and owned by Inserm. BioPredic sells undifferentiated cell line (HPR101) that can be expanded, passaged, and frozen in-house to prepare a cell bank and differentiated ready-to-use cells, HPR116 (Cellosaurus=CVCL_WL73) that can be used immediately or in a few days after thawing, as a single-use disposable product (Biopredic)., Anecdotal: The 'RG' in the cell name stands for 'Rumin' and 'Gripon', the two scientists that were influential in the establishment of this cell line., Characteristics: Cell line main applications are sugar and lipid metabolism, physiopathology; drug metabolism and toxicology and viral infection., Characteristics: Can be induced to differentiate into hepatocyte-like cells by exposure to DMSO., Group: Patented cell line.
Proper citation: Millipore Cat# C103485, RRID:CVCL_9720 Copy
Misidentified Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4226
Organism: Anguilla japonica (Japanese eel)
Disease:
Category: Spontaneously immortalized cell line
Comments: Problematic cell line: Misidentified. Originally thought to be of tilapia origin (Oreochromis niloticus) but found to be from eel (DOI=10.1007/s12562-018-1215-4; RCB). Is probably identical to Hepa-E1.., Group: Fish cell line.
Proper citation: ECACC Cat# 99072813, RRID:CVCL_4226 Copy
Misidentified Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4226
Organism: Anguilla japonica (Japanese eel)
Disease:
Category: Spontaneously immortalized cell line
Comments: Problematic cell line: Misidentified. Originally thought to be of tilapia origin (Oreochromis niloticus) but found to be from eel (DOI=10.1007/s12562-018-1215-4; RCB). Is probably identical to Hepa-E1.., Group: Fish cell line.
Proper citation: RRID:CVCL_4226 Copy
Misidentified Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4226
Organism: Anguilla japonica (Japanese eel)
Disease:
Category: Spontaneously immortalized cell line
Comments: Problematic cell line: Misidentified. Originally thought to be of tilapia origin (Oreochromis niloticus) but found to be from eel (DOI=10.1007/s12562-018-1215-4; RCB). Is probably identical to Hepa-E1.., Group: Fish cell line.
Proper citation: RCB Cat# RCB1156, RRID:CVCL_4226 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_9720
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Miscellaneous: This cell line is exclusively produced and controlled by Biopredic International and owned by Inserm. BioPredic sells undifferentiated cell line (HPR101) that can be expanded, passaged, and frozen in-house to prepare a cell bank and differentiated ready-to-use cells, HPR116 (Cellosaurus=CVCL_WL73) that can be used immediately or in a few days after thawing, as a single-use disposable product (Biopredic)., Anecdotal: The 'RG' in the cell name stands for 'Rumin' and 'Gripon', the two scientists that were influential in the establishment of this cell line., Characteristics: Cell line main applications are sugar and lipid metabolism, physiopathology; drug metabolism and toxicology and viral infection., Characteristics: Can be induced to differentiate into hepatocyte-like cells by exposure to DMSO., Group: Patented cell line.
Proper citation: RRID:CVCL_9720 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_DC15
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Acts through the activation of a luciferase reporter gene which is under the control of dioxin-response elements (DREs) from mouse Cyp1a1 gene., Biotechnology: Can be used for bioassays to detect dioxin/TCDD-like compounds., Group: Patented cell line.
Proper citation: RRID:CVCL_DC15 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_M177
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Virology: Inducibly expresses a hepatitis B virus (HBV) genome under the control of a tet operator/CMV promoter. Upon removal of tetracycline the cell line produces viral RNA and secrete virus-like particles into the supernatant., Biotechnology: Used in a bioassay that permits the large-scale screening of compound libraries for inhibitors of HBV replication., Population: Caucasian., Group: Patented cell line.
Proper citation: RRID:CVCL_M177 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_TZ61
Organism: Homo sapiens (Human)
Disease: Adult hepatocellular carcinoma
Category: Cancer cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: RRID:CVCL_TZ61 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_5I95
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_5I95 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_8560
Organism: Homo sapiens (Human)
Disease: Hepatoblastoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_8560 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4525
Organism: Mus musculus (Mouse)
Disease:
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: RRID:CVCL_4525 Copy
Possibly Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_3290
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Part of: Wistar Institute Special Collection vascular cell lines.
Proper citation: Coriell Cat# WC00114, RRID:CVCL_3290 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0E13
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Part of: Wistar Institute Special Collection vascular cell lines.
Proper citation: RRID:CVCL_0E13 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3289
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Senescence: Capable of at least 37 PDL (ATCC=CRL-2608)., Part of: Wistar Institute Special Collection vascular cell lines.
Proper citation: ATCC Cat# CRL-2608, RRID:CVCL_3289 Copy
Possibly Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_3288
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Part of: Wistar Institute Special Collection vascular cell lines.
Proper citation: Coriell Cat# WC00108, RRID:CVCL_3288 Copy
Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_3288
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Part of: Wistar Institute Special Collection vascular cell lines.
Proper citation: ATCC Cat# CRL-2599, RRID:CVCL_3288 Copy
Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_3288
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Part of: Wistar Institute Special Collection vascular cell lines.
Proper citation: RRID:CVCL_3288 Copy
Possibly Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_3291
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Senescence: Capable of at least 36 PDL (ATCC=CRL-2475)., Part of: Wistar Institute Special Collection vascular cell lines.
Proper citation: Coriell Cat# WC00100, RRID:CVCL_3291 Copy
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