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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_1702
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Population: Caucasian., From: Memorial Sloan Kettering Cancer Center; New York; USA., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1702 Copy
https://web.expasy.org/cellosaurus/CVCL_0528
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Characteristics: Substrate-adherent type (S-type) (PubMed=15720811)., Population: Caucasian., From: Memorial Sloan Kettering Cancer Center; New York; USA., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0528 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0532
Organism: Homo sapiens (Human)
Disease: Ovarian serous cystadenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian., From: Memorial Sloan Kettering Cancer Center; New York; USA., Part of: OCCP ovarian cancer cell line panel., Part of: NCI-60 cancer cell line panel., Part of: MD Anderson Cell Lines Project., Part of: KuDOS 95 cell line panel., Part of: JFCR39 cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0532 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0098
Organism: Homo sapiens (Human)
Disease: Adult acute myeloid leukemia
Category: Cancer cell line
Comments: Caution: TP53 mutation indicated incorrectly as being at p.Tyr327His (c.981T>C) in PubMed=8136267., Population: Japanese., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0098 Copy
https://web.expasy.org/cellosaurus/CVCL_1704
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related cervical squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1704 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_2795
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related cervical squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: JCRB Cat# IFO50311, RRID:CVCL_2795 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_2795
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related cervical squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_2795 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_1707
Organism: Homo sapiens (Human)
Disease: Endometrial adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Possibly contaminated. HHUA (distributed by RCB) and SNG-M (distributed by JCRB) share similar STR profiles and have been established by the same research group. While HHUA was described in 1984 and SNG-M in 1977 it has not been possible to establish which of the two cell lines are derived from each other. Thus it has been decided to consider them as being sister cell lines originating from the same donor..
Proper citation: RRID:CVCL_1707 Copy
Contaminated Contaminated Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_0535
Organism: Homo sapiens (Human)
Disease: Astrocytoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: NCI-60 cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Contaminated. Shown to be a U-251MG derivative (PubMed=18304946; PubMed=20143388; PubMed=22570425). Originally thought to originate from a 47 year old patient with a left parieto-occipital glioblastoma..
Proper citation: RRID:CVCL_0535 Copy
https://web.expasy.org/cellosaurus/CVCL_0076
Organism: Homo sapiens (Human)
Disease: Gastric adenocarcinoma
Category: Cancer cell line
Comments: Population: Korean., Part of: TCGA-110-CL cell line panel., Part of: Seoul National University (SNU) cell line collection., Part of: MYC genetic alteration cell panel (ATCC TCP-1035)., Part of: MD Anderson Cell Lines Project., Part of: FGFR genetic alteration cell panel (ATCC TCP-1034)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0076 Copy
https://web.expasy.org/cellosaurus/CVCL_0250
Organism: Homo sapiens (Human)
Disease: Adult hepatocellular carcinoma
Category: Cancer cell line
Comments: Population: Korean., Part of: Seoul National University (SNU) cell line collection., Part of: MD Anderson Cell Lines Project., Part of: Liver Cancer Model Repository (LIMORE)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0250 Copy
https://web.expasy.org/cellosaurus/CVCL_0077
Organism: Homo sapiens (Human)
Disease: Adult hepatocellular carcinoma
Category: Cancer cell line
Comments: Karyotypic information: Has lost chromosome Y., Population: Korean., Part of: Seoul National University (SNU) cell line collection., Part of: MD Anderson Cell Lines Project., Part of: Liver Cancer Model Repository (LIMORE)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0077 Copy
https://web.expasy.org/cellosaurus/CVCL_0366
Organism: Homo sapiens (Human)
Disease: Adult hepatocellular carcinoma
Category: Cancer cell line
Comments: Population: Korean., Part of: Seoul National University (SNU) cell line collection., Part of: MD Anderson Cell Lines Project., Part of: Liver Cancer Model Repository (LIMORE)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0366 Copy
https://web.expasy.org/cellosaurus/CVCL_1136
Organism: Homo sapiens (Human)
Disease: Breast carcinoma
Category: Cancer cell line
Comments: Caution: Previously erroneously indicated as originating from a male patient, correct sex assignment from Moore G.E. in a personal communication to the authors of PubMed=9892114., Population: African American., Part of: MD Anderson Cell Lines Project., Part of: JWGray breast cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: CLS Cat# 300463, RRID:CVCL_1136 Copy
Misidentified Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_4362
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Karyotypic information: Near triploid with the modal number of 67 chromosomes (ATCC=HTB-124)., Virology: Contains 2 copies of the SV40 genome, one complete the other incomplete tandemly integrated in the cell line genome., Part of: JWGray breast cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (PubMed=16643607; PubMed=20143388). Originally thought to originate from a casein-producing breast cell line from a 27 year old Caucasian woman. In addition contains SV40 genomic sequence while the cell line was deemed to be spontaneously immortalized..
Proper citation: CLS Cat# 300178, RRID:CVCL_4362 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0030
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: HeLa is the most frequent contributor to cell lines contamination., Anecdotal: Was flown since the 1960s on at least ten different space missions: Korabl-Sputnik-2, Vostok-1, Vostok-4, Vostok-5 and Vostok-6, Voshkod 1 and Zond-5, Discoverer XVIII, Progress M-35/Mir and Shuttle STS-89., Anecdotal: The HeLa cell line and its story inspired Australian artist Cynthia Verspaget to embark in 2003 on a artistic project 'The Anarchy Cell Line' (TAnCL) where she mixed her blood with HeLa cells. This work later spawned a PhD thesis (CelloPub=CLPUB00376) where among other things she makes the observation that two main taxonomical distinctions present in the zombie, living/dead and human/nonhuman, are also present in the HeLa cell line., Anecdotal: The fascinating story of the HeLa cell line and of Henrietta Lacks from whom these cells originate are described in the book of Rebecca Skloot (CelloPub=CLPUB00377)., Anecdotal: The HeLa cell line which was established in February 1951 is the oldest human immortal cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: HeLa has 5 five HPV18 integration sites: three on normal chromosomes 8 at 8q24 and two on derivative chromosomes, der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22) (q24;q13)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Proper citation: CLS Cat# 300194, RRID:CVCL_0030 Copy
Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0346
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Characteristics: Neuroblastic type (N-type)., Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: CLS Cat# 300148, RRID:CVCL_0346 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0440
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Senescence: Capable of attaining 42-46 population doublings before the onset of senescence (ATCC=CCL-171). Senesces at 26 PDL (PubMed=17395773)., Biotechnology: Used for the production of the live zoster vaccine (Trade name: Zostavax)., Biotechnology: Used for the production of the live varicella virus vaccine (Trade name: Varivax)., Biotechnology: Used for the production of the Hepatitis A vaccines Avaxim, Epaxal, Havrix and Vaqta., Biotechnology: Used for the production of the Human Diploid Cell Vaccine (HDCV) against rabies (Trade name: Imovax Rabies)., Group: Vaccine production cell line.
Proper citation: CLS Cat# 300395, RRID:CVCL_0440 Copy
https://web.expasy.org/cellosaurus/CVCL_3612
Organism: Homo sapiens (Human)
Disease: Ovarian endometrioid adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: OCCP ovarian cancer cell line panel., Part of: MD Anderson Cell Lines Project., Part of: KuDOS 95 cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Patented cell line.
Proper citation: RRID:CVCL_3612 Copy
https://web.expasy.org/cellosaurus/CVCL_3611
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma germinal center B-cell type
Category: Cancer cell line
Comments: Population: Caucasian., Part of: MD Anderson Cell Lines Project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_3611 Copy
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