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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_2078
Organism: Homo sapiens (Human)
Disease: Plasma cell myeloma
Category: Cancer cell line
Comments: Miscellaneous: HLA typing from personal communication of Pellat-Deceunynck, Catherine., Characteristics: IL6 independent., Characteristics: Produces IgA1 kappa., Population: Caucasian., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2078 Copy
https://web.expasy.org/cellosaurus/CVCL_D605
Organism: Homo sapiens (Human)
Disease: Primary central chondrosarcoma
Category: Cancer cell line
Proper citation: RRID:CVCL_D605 Copy
https://web.expasy.org/cellosaurus/CVCL_2080
Organism: Homo sapiens (Human)
Disease: Pleural epithelioid mesothelioma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: TCGA-110-CL cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2080 Copy
https://web.expasy.org/cellosaurus/CVCL_0004
Organism: Homo sapiens (Human)
Disease: Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
Category: Cancer cell line
Comments: Population: Caucasian., Part of: NCI-60 cancer cell line panel., Part of: MD Anderson Cell Lines Project., Part of: LL-100 blood cancer cell line panel., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 1., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0004 Copy
https://web.expasy.org/cellosaurus/CVCL_1323
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1323 Copy
https://web.expasy.org/cellosaurus/CVCL_2529
Organism: Homo sapiens (Human)
Disease: Type I endometrial adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: DepMap data are indicated for Ishidisconkawa (Heraklio) 02 ER- (CVCL_6543), but the referenced ECACC provider corresponds to Ishikawa (CVCL_2529)., Population: Japanese., Part of: ENCODE project common cell types; tier 3.
Proper citation: RRID:CVCL_2529 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_2805
Organism: Homo sapiens (Human)
Disease: Adult hepatocellular carcinoma
Category: Cancer cell line
Comments: Virology: Contains 2 copies of integrated incomplete hepatitis B virus (HBV) genomes. Does not secrete hepatitis virus B surface antigen (HBsAg) (PubMed=1701409; PubMed=2174476)., Population: Japanese., Part of: MD Anderson Cell Lines Project., Part of: Liver Cancer Model Repository (LIMORE)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2805 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0364
Organism: Homo sapiens (Human)
Disease: Adult hepatocellular carcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: TCGA-110-CL cell line panel., Part of: Liver Cancer Model Repository (LIMORE)., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0364 Copy
https://web.expasy.org/cellosaurus/CVCL_3073
Organism: Homo sapiens (Human)
Disease: Gestational choriocarcinoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: JCRB Cat# IFO50322, RRID:CVCL_3073 Copy
https://web.expasy.org/cellosaurus/CVCL_1136
Organism: Homo sapiens (Human)
Disease: Breast carcinoma
Category: Cancer cell line
Comments: Caution: Previously erroneously indicated as originating from a male patient, correct sex assignment from Moore G.E. in a personal communication to the authors of PubMed=9892114., Population: African American., Part of: MD Anderson Cell Lines Project., Part of: JWGray breast cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: CLS Cat# 300463, RRID:CVCL_1136 Copy
Misidentified Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_4362
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Karyotypic information: Near triploid with the modal number of 67 chromosomes (ATCC=HTB-124)., Virology: Contains 2 copies of the SV40 genome, one complete the other incomplete tandemly integrated in the cell line genome., Part of: JWGray breast cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (PubMed=16643607; PubMed=20143388). Originally thought to originate from a casein-producing breast cell line from a 27 year old Caucasian woman. In addition contains SV40 genomic sequence while the cell line was deemed to be spontaneously immortalized..
Proper citation: CLS Cat# 300178, RRID:CVCL_4362 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0030
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: HeLa is the most frequent contributor to cell lines contamination., Anecdotal: Was flown since the 1960s on at least ten different space missions: Korabl-Sputnik-2, Vostok-1, Vostok-4, Vostok-5 and Vostok-6, Voshkod 1 and Zond-5, Discoverer XVIII, Progress M-35/Mir and Shuttle STS-89., Anecdotal: The HeLa cell line and its story inspired Australian artist Cynthia Verspaget to embark in 2003 on a artistic project 'The Anarchy Cell Line' (TAnCL) where she mixed her blood with HeLa cells. This work later spawned a PhD thesis (CelloPub=CLPUB00376) where among other things she makes the observation that two main taxonomical distinctions present in the zombie, living/dead and human/nonhuman, are also present in the HeLa cell line., Anecdotal: The fascinating story of the HeLa cell line and of Henrietta Lacks from whom these cells originate are described in the book of Rebecca Skloot (CelloPub=CLPUB00377)., Anecdotal: The HeLa cell line which was established in February 1951 is the oldest human immortal cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: HeLa has 5 five HPV18 integration sites: three on normal chromosomes 8 at 8q24 and two on derivative chromosomes, der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22) (q24;q13)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Proper citation: CLS Cat# 300194, RRID:CVCL_0030 Copy
Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0346
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Characteristics: Neuroblastic type (N-type)., Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: CLS Cat# 300148, RRID:CVCL_0346 Copy
https://web.expasy.org/cellosaurus/CVCL_4996
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related cervical squamous cell carcinoma
Category: Cancer cell line
Comments: Virology: Contains a partial HPV45 genome., Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: CLS Cat# 305115, RRID:CVCL_4996 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0440
Organism: Homo sapiens (Human)
Category: Finite cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Senescence: Capable of attaining 42-46 population doublings before the onset of senescence (ATCC=CCL-171). Senesces at 26 PDL (PubMed=17395773)., Biotechnology: Used for the production of the live zoster vaccine (Trade name: Zostavax)., Biotechnology: Used for the production of the live varicella virus vaccine (Trade name: Varivax)., Biotechnology: Used for the production of the Hepatitis A vaccines Avaxim, Epaxal, Havrix and Vaqta., Biotechnology: Used for the production of the Human Diploid Cell Vaccine (HDCV) against rabies (Trade name: Imovax Rabies)., Group: Vaccine production cell line.
Proper citation: CLS Cat# 300395, RRID:CVCL_0440 Copy
https://web.expasy.org/cellosaurus/CVCL_0168
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Part of: Small cell lung cancer p53 hotspot mutation cell panel (ATCC TCP-2040)., Group: Patented cell line.
Proper citation: CLS Cat# 300311, RRID:CVCL_0168 Copy
https://web.expasy.org/cellosaurus/CVCL_6573
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: ATCC Cat# CRL-4001, RRID:CVCL_6573 Copy
Misclassified
https://web.expasy.org/cellosaurus/CVCL_0235
Organism: Homo sapiens (Human)
Disease: Papillary renal cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., From: Memorial Sloan Kettering Cancer Center; New York; USA., Part of: MD Anderson Cell Lines Project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misclassified. Originally thought to be a clear cell renal cell carcinoma but shown to be from a papillary renal cell carcinoma (PubMed=17409424; PubMed=27993170)..
Proper citation: CancerTools Cat# 161904, RRID:CVCL_0235 Copy
https://web.expasy.org/cellosaurus/CVCL_4996
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related cervical squamous cell carcinoma
Category: Cancer cell line
Comments: Virology: Contains a partial HPV45 genome., Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: Ubigene Cat# YC-C123, RRID:CVCL_4996 Copy
https://web.expasy.org/cellosaurus/CVCL_2505
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16., Population: African American.
Proper citation: ECACC Cat# 95091409, RRID:CVCL_2505 Copy
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