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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Possibly Misidentified/Contaminated
https://web.expasy.org/cellosaurus/CVCL_V613
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Probably misidentified/contaminated. Except of a loss of an allele of TH01 the STR profile of SF172 is identical to that of SF763. Furthermore we could not find in the literature any trace of the exact origin of SF172. According to the UCSF Biorepository, there is no record of SF172 in their system while SF763 is registered there (personal communication of Shai, Anny). The TP53 mutation recorded for SF763 is also identical to the one in SF172..
Proper citation: RRID:CVCL_V613 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_6950
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related cervical squamous cell carcinoma
Category: Cancer cell line
Comments: Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3111C0001CCC000051). It was one of the sources for the STR profile of this entry., Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Contaminated. Shown to be a ME-180 derivative (PubMed=22570425)..
Proper citation: RRID:CVCL_6950 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3163
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments:
Proper citation: RRID:CVCL_3163 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3163
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments:
Proper citation: JCRB Cat# NIHS0016, RRID:CVCL_3163 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3163
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments:
Proper citation: JCRB Cat# JCRB0075, RRID:CVCL_3163 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: KCB Cat# KCB 92018YJ, RRID:CVCL_0549 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_RK68
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Senescence: Senesces at 34 PDL (PubMed=17395773)., Population: Japanese., Part of: Ban's atomic bomb survivor-derived skin fibroblast library.
Proper citation: RRID:CVCL_RK68 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: ATCC Cat# CRL-1711, RRID:CVCL_0549 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: ECACC Cat# 89070101, RRID:CVCL_0549 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: RRID:CVCL_0549 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4U10
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Biotechnology: Used for the production of the porcine circovirus 2 (PCV2) vaccine CircoFLEX. Used to produce the PCV2 ORF2 capsid protein (PubMed=29133148)., Biotechnology: Used for the production of the influenza virus vaccine FluBlok. Used to produce the hemagglutinin (HA) of influenza A subtype H1N1, H3N2 and of influenza B (PubMed=19453397)., Group: Vaccine production cell line., Group: Recombinant protein production insect cell line., Group: Patented cell line., Group: Insect cell line.
Proper citation: RRID:CVCL_4U10 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: RCB Cat# RCB0563, RRID:CVCL_0549 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_RK68
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Senescence: Senesces at 34 PDL (PubMed=17395773)., Population: Japanese., Part of: Ban's atomic bomb survivor-derived skin fibroblast library.
Proper citation: RCB Cat# RCB0581, RRID:CVCL_RK68 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_0019
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Virology: Low susceptibility to infection by Zika virus (ZIKV) (PubMed=29468137)., Characteristics: Particularly suitable for research in neurodegenerative diseases due to the fact that it has a specific uptake of norepinephrine (NA), expresses bona fide neurofilament proteins, and shows activity of enzymes involved in catecholaminergic systems (tyrosine and dopamine-beta-hydroxylases) (PubMed=35893584)., Characteristics: There seem to be differences in the retinoic acid (RA)-induced neuronal phenotype of SH-SY5Y cells from ATCC and ECACC. After 5 days of RA treatment, ECACC cells are slightly larger in size and contains significant amount of neuroblastic (N-type) cells and a small fraction of epithelial (S-type) cells (PubMed=18957096)., Characteristics: Neuroblastic type (N-type) (PubMed=15720811)., Population: Caucasian., From: Memorial Sloan Kettering Cancer Center; New York; USA., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 3., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Partially contaminated. Some laboratories that are redistributing this cell line are in fact redistributing a contaminated cell line of mouse origin (PubMed=25182563)..
Proper citation: RRID:CVCL_0019 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0F47
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Characteristics: Substrate-adherent type (S-type) (PubMed=15720811)., Population: Caucasian.
Proper citation: RRID:CVCL_0F47 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_RK37
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Parent cell line (SGC-7901) has been shown to be a HeLa derivative..
Proper citation: RRID:CVCL_RK37 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_0520
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: Formerly the CCRID database had 2 entries describing this cell line (3111C0001CCC000236, 3131C0001000700046). They were one of the sources for the STR profile of this entry., Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706; PubMed=28851942). Originally thought to originate from the lymph node of a 56 year old female patient with a gastric carcinoma..
Proper citation: CCTCC Cat# GDC0150, RRID:CVCL_0520 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_B0A1
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Parent cell line (SGC-7901) has been shown to be a HeLa derivative..
Proper citation: RRID:CVCL_B0A1 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_VU57
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Parent cell line (SGC-7901) has been shown to be a HeLa derivative..
Proper citation: RRID:CVCL_VU57 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_V314
Organism: Felis catus (Cat)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Persistently infected by feline immunodeficiency virus (FIV) isolate Shi., Characteristics: IL2 dependent., Group: Patented cell line.
Proper citation: RRID:CVCL_V314 Copy
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