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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: CLS Cat# 604328, RRID:CVCL_0549 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0059
Organism: Chlorocebus sabaeus (Green monkey)
Disease:
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank=DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603)., Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank=DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain., Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia)., Biotechnology: Used for the production of the live smallpox (vaccinia) vaccine (Trade name: ACAM2000)., Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix)., Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV)., Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB)., Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio)., Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Non-human primate cell line.
Proper citation: CLS Cat# 605372, RRID:CVCL_0059 Copy
Misidentified Discontinued
https://web.expasy.org/cellosaurus/CVCL_3845
Organism: Chlorocebus pygerythrus (Vervet monkey)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Virology: Susceptible to infection by many viruses (arboviruses, reoviruses, rotaviruses, etc.)., Problematic cell line: Misidentified. Originally thought to be of Rhesus macaque origin but found to be from African Green monkey (PubMed=4043530; PubMed=20143388) and more precisely from Chlorocebus pygerythrus (PubMed=34737324).., Group: Non-human primate cell line.
Proper citation: CLS Cat# 305007, RRID:CVCL_3845 Copy
Misidentified Misidentified Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4540
Organism: Chlorocebus pygerythrus (Vervet monkey)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Highly susceptible to infection by porcine reproductive and respiratory syndrome virus (PRRSV)., Problematic cell line: Misidentified. Parent cell line (MA-104) has been shown to be from African Green monkey instead of Rhesus macaque.., Group: Patented cell line., Group: Non-human primate cell line.
Proper citation: CLS Cat# 305006, RRID:CVCL_4540 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0593
Organism: Neovison vison (American mink)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Susceptible to infection by SARS coronavirus (SARS-CoV) (PubMed=15731278)., Virology: Susceptible to infection and replication of influenza A and B viruses (PubMed=9817906)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: CLS Cat# 305192, RRID:CVCL_0593 Copy
Contaminated Contaminated Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_0238
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=1246601; PubMed=20143388; PubMed=21656536). Originally thought to originate from normal hepatic cells obtained from a liver biopsy of an adult..
Proper citation: CLS Cat# 300139, RRID:CVCL_0238 Copy
Partially Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_2309
Organism: Homo sapiens (Human)
Disease: Laryngeal squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Partially contaminated. The ICLC stock (now discontinued) was found to be contaminated, probably by U-251MG (Cellosaurus=CVCL_0021)..
Proper citation: CancerTools Cat# 152843, RRID:CVCL_2309 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WI
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: RRID:CVCL_A5WI Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WF
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: RRID:CVCL_A5WF Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WI
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: Coriell Cat# GM16292, RRID:CVCL_A5WI Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WL
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: Coriell Cat# GM16295, RRID:CVCL_A5WL Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WK
Organism: Homo sapiens (Human)
Disease: Facioscapulohumeral muscular dystrophy 1
Category: Transformed cell line
Comments:
Proper citation: RRID:CVCL_A5WK Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WC
Organism: Homo sapiens (Human)
Disease: Facioscapulohumeral muscular dystrophy 1
Category: Transformed cell line
Comments:
Proper citation: RRID:CVCL_A5WC Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WD
Organism: Homo sapiens (Human)
Disease: Facioscapulohumeral muscular dystrophy 1
Category: Transformed cell line
Comments:
Proper citation: RRID:CVCL_A5WD Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WH
Organism: Homo sapiens (Human)
Disease: Facioscapulohumeral muscular dystrophy 1
Category: Transformed cell line
Comments:
Proper citation: RRID:CVCL_A5WH Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WL
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: RRID:CVCL_A5WL Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WM
Organism: Homo sapiens (Human)
Disease: Facioscapulohumeral muscular dystrophy 1
Category: Transformed cell line
Comments:
Proper citation: RRID:CVCL_A5WM Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_A5WR
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: Coriell Cat# GM16330, RRID:CVCL_A5WR Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0H58
Organism: Homo sapiens (Human)
Disease: Tourette syndrome
Category: Transformed cell line
Comments:
Proper citation: RRID:CVCL_0H58 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0H57
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: Coriell Cat# GM16434, RRID:CVCL_0H57 Copy
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