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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Contaminated
https://web.expasy.org/cellosaurus/CVCL_8441
Organism: Homo sapiens (Human)
Disease: Childhood acute myeloid leukemia
Category: Cancer cell line
Comments: Population: African American and Caucasian., Problematic cell line: Contaminated. Shown to be a AML-193 derivative (PubMed=12592342; PubMed=20143388). Originally thought to originate from the peripheral blood of a 22 year old male patient with acute lymphoblastic leukemia..
Proper citation: RRID:CVCL_8441 Copy
Misidentified/Contaminated
https://web.expasy.org/cellosaurus/CVCL_L986
Organism: Aotus trivirgatus (Three-striped night monkey)
Disease:
Category: Undefined cell line type
Comments: Anecdotal: Part of a set of 4 cell lines that were fraudulently stated to originate from Hodgkin lymphoma (PubMed=265539)., Problematic cell line: Misidentified/contaminated. Originally thought to be of human origin but found to derive from Aotus trivirgatus OMK-210 (PubMed=7192801; PubMed=12592342; PubMed=20143388).., Group: Non-human primate cell line.
Proper citation: RRID:CVCL_L986 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0551
Organism: Homo sapiens (Human)
Disease: Oral cavity squamous cell carcinoma
Category: Cancer cell line
Comments: Part of: MD Anderson Cell Lines Project.
Proper citation: RRID:CVCL_0551 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_2200
Organism: Homo sapiens (Human)
Disease: Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
Category: Cancer cell line
Comments: Population: Caucasian., Problematic cell line: Contaminated. Shown to be a K-562 derivative (PubMed=10508494; PubMed=12592342; PubMed=20143388)..
Proper citation: RRID:CVCL_2200 Copy
Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_8273
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=16643607; PubMed=20143388). Originally thought to originate from a lung carcinoma..
Proper citation: RRID:CVCL_8273 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_4902
Organism: Homo sapiens (Human)
Disease: Intrahepatic cholangiocarcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: JFCR45 cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Part of: Biliary tract cancer cell line atlas., Problematic cell line: Contaminated. Shown to be a ETK-1 derivative (RCB=RCB1293). Originally thought to originate from a 64 year old female patient with an intrahepatic cholangiocarcinoma..
Proper citation: RRID:CVCL_4902 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_Y456
Organism: Sorex trowbridgii (Trowbridge's shrew)
Disease:
Category: Finite cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: ATCC Cat# CRL-6552, RRID:CVCL_Y456 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_5586
Organism: Suncus murinus (Asian house shrew)
Disease:
Category: Finite cell line
Comments:
Proper citation: RRID:CVCL_5586 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_JG84
Organism: Homo sapiens (Human)
Disease: Lung small cell carcinoma
Category: Cancer cell line
Comments:
Proper citation: JCRB Cat# KURB2687, RRID:CVCL_JG84 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0F69
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments:
Proper citation: RRID:CVCL_0F69 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_JG84
Organism: Homo sapiens (Human)
Disease: Lung small cell carcinoma
Category: Cancer cell line
Comments:
Proper citation: RRID:CVCL_JG84 Copy
Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_3162
Organism: Homo sapiens (Human)
Disease: Melanoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_3162 Copy
Possibly Misidentified/Contaminated
https://web.expasy.org/cellosaurus/CVCL_V613
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Probably misidentified/contaminated. Except of a loss of an allele of TH01 the STR profile of SF172 is identical to that of SF763. Furthermore we could not find in the literature any trace of the exact origin of SF172. According to the UCSF Biorepository, there is no record of SF172 in their system while SF763 is registered there (personal communication of Shai, Anny). The TP53 mutation recorded for SF763 is also identical to the one in SF172..
Proper citation: RRID:CVCL_V613 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_6950
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related cervical squamous cell carcinoma
Category: Cancer cell line
Comments: Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3111C0001CCC000051). It was one of the sources for the STR profile of this entry., Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Contaminated. Shown to be a ME-180 derivative (PubMed=22570425)..
Proper citation: RRID:CVCL_6950 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3163
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments:
Proper citation: RRID:CVCL_3163 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3163
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments:
Proper citation: JCRB Cat# NIHS0016, RRID:CVCL_3163 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_3163
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments:
Proper citation: JCRB Cat# JCRB0075, RRID:CVCL_3163 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: KCB Cat# KCB 92018YJ, RRID:CVCL_0549 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_RK68
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Senescence: Senesces at 34 PDL (PubMed=17395773)., Population: Japanese., Part of: Ban's atomic bomb survivor-derived skin fibroblast library.
Proper citation: RRID:CVCL_RK68 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: ATCC Cat# CRL-1711, RRID:CVCL_0549 Copy
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