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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_E2Y4
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Miscellaneous: Cell line information from personal communication of Sattler, Christian., Characteristics: Using pcDNA5/FRT/TO and pOG44, P2RX2 isoform B with p.Val60Leu and P2RX3 were integrated in a single site and their expression is regulated by tetracycline.
Proper citation: RRID:CVCL_E2Y4 Copy
https://web.expasy.org/cellosaurus/CVCL_E0W2
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: Transfected with two plasmids, XLone-GemininT25D and pCMV-hyPBase. The XLone-GemininT25D plasmid contains in one orientation a EF1A-rtTA-P2A-Bsd region where rtTA is a reverse tetracycline-controlled transactivator, a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16 and in the other orientation a TRE3G-GemininT25D region thus allowing the doxycycline induction of gemimin (DOI=10.1101/2024.02.02.578516)., Population: Caucasian.
Proper citation: RRID:CVCL_E0W2 Copy
https://web.expasy.org/cellosaurus/CVCL_E0W0
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: Using CRISPR/Cas9 the fluorescent protein mClover was integrated at the C-terminus of MTBP (from parent cell line HCT-116 MTBP-mClover)., Characteristics: Transfected with two plasmids, XLone-GemininT25D and pCMV-hyPBase. The XLone-GemininT25D plasmid contains in one orientation a EF1A-rtTA-P2A-Bsd region where rtTA is a reverse tetracycline-controlled transactivator, a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16 and in the other orientation a TRE3G-GemininT25D region thus allowing the doxycycline induction of gemimin (DOI=10.1101/2024.02.02.578516)., Population: Caucasian.
Proper citation: RRID:CVCL_E0W0 Copy
https://web.expasy.org/cellosaurus/CVCL_E2Y5
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Miscellaneous: Cell line information from personal communication of Sattler, Christian., Characteristics: Using pcDNA5/FRT/TO and pOG44, P2RX2 isoform B with p.Asp273Tyr and P2RX3 were integrated in a single site and their expression is regulated by tetracycline.
Proper citation: RRID:CVCL_E2Y5 Copy
https://web.expasy.org/cellosaurus/CVCL_E1HB
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: Cell line information from personal communication of Adriaenssens, Elias., Population: African American.
Proper citation: RRID:CVCL_E1HB Copy
https://web.expasy.org/cellosaurus/CVCL_E1HA
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: Cell line information from personal communication of Adriaenssens, Elias., Population: African American.
Proper citation: RRID:CVCL_E1HA Copy
https://web.expasy.org/cellosaurus/CVCL_E1HL
Organism: Mus musculus (Mouse)
Category: Hybridoma
Proper citation: RRID:CVCL_E1HL Copy
https://web.expasy.org/cellosaurus/CVCL_E2RM
Organism: Mus musculus (Mouse)
Category: Hybridoma
Proper citation: RRID:CVCL_E2RM Copy
https://web.expasy.org/cellosaurus/CVCL_E4JW
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Miscellaneous: Cell line information from personal communication of Yuste-Checa, Patricia., Characteristics: Additional transduction with a construct encoding for the LysoTag, the lysosomal protein TMEM192 tagged with 3xHA (Direct_author_submission)., Characteristics: Additional expression of a plasmid encoding a bicistronic IRES construct of EGFP-tagged RNF152, along with an mScarlet-I transfection marker (from parent cell line HEK293T TetOff-SNCA-A53T EGFP-RNF152-IRES-mScarlet-I)., Characteristics: Transduced with an all-in-one TetOff construct for the controllable expression of untagged SNCA p.Ala53Thr (from parent cell line HEK293T TetOff-SNCA-A53T EGFP-RNF152-IRES-mScarlet-I).
Proper citation: RRID:CVCL_E4JW Copy
https://web.expasy.org/cellosaurus/CVCL_E3Y2
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: Miscellaneous: Cell line information from personal communication of Harper, Jeffrey Wade., Characteristics: Using CRISPR/Cas9 a TRE3G promoter driven NEUROG2 construct was introduced in the AAVS1 safe harbor locus (from parent cell line KOLF2.1J AAVS1-TREG3-NGN2)., Population: Caucasian; British.
Proper citation: RRID:CVCL_E3Y2 Copy
https://web.expasy.org/cellosaurus/CVCL_E3Y1
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: Miscellaneous: Cell line information from personal communication of Harper, Jeffrey Wade., Characteristics: Using CRISPR/Cas9 a TRE3G promoter driven NEUROG2 construct was introduced in the AAVS1 safe harbor locus (from parent cell line KOLF2.1J AAVS1-TREG3-NGN2)., Population: Caucasian; British.
Proper citation: RRID:CVCL_E3Y1 Copy
https://web.expasy.org/cellosaurus/CVCL_E4SL
Organism: Homo sapiens (Human)
Disease: Alzheimer's disease 4
Category: Induced pluripotent stem cell
Comments: Population: Caucasian; British., From: The Jackson Laboratory; Bar Harbor; USA.
Proper citation: RRID:CVCL_E4SL Copy
https://web.expasy.org/cellosaurus/CVCL_E3G5
Organism: Homo sapiens (Human)
Category: Transformed cell line
Proper citation: RRID:CVCL_E3G5 Copy
https://web.expasy.org/cellosaurus/CVCL_W168
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Comments: Miscellaneous: Cell line name and sex of donor from author direct submission.
Proper citation: Ximbio Cat# 152138, RRID:CVCL_W168 Copy
https://web.expasy.org/cellosaurus/CVCL_W185
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Proper citation: Ximbio Cat# 152137, RRID:CVCL_W185 Copy
https://web.expasy.org/cellosaurus/CVCL_B046
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Proper citation: ATCC Cat# CRL-2979, RRID:CVCL_B046 Copy
https://web.expasy.org/cellosaurus/CVCL_A9A2
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Comments: Characteristics: Expression of the Csf1 gene is driven by the chicken beta-actin promoter and the human cytomegalovirus enhancer (PubMed=10934646).
Proper citation: RCB Cat# RCB5036, RRID:CVCL_A9A2 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_6888
Organism: Homo sapiens (Human)
Category: Hybrid cell line
Comments: Problematic cell line: Contaminated. On the basis of the STR profile (PubMed=18196576) it is identical to CNE-2 and seems to be a hybrid of HeLa and of cell line of unknown origin. This is also confirmed by RNASeq data from PubMed=24991015. Originally thought to originate from a 58 year old female patient with a nasopharyngeal carcinoma..
Proper citation: Ubigene Cat# YC-C062, RRID:CVCL_6888 Copy
https://web.expasy.org/cellosaurus/CVCL_ZJ60
Organism: Mus musculus (Mouse)
Disease: Mouse glioblastoma
Category: Cancer cell line
Comments: Characteristics: Transduced with a lentiviral vector containing a Fluc-IRES-GFP construct expressed under the control of the CMV promoter.
Proper citation: Millipore Cat# SCC195, RRID:CVCL_ZJ60 Copy
https://web.expasy.org/cellosaurus/CVCL_6773
Organism: Mus musculus (Mouse)
Category: Finite cell line
Proper citation: ATCC Cat# CRL-2613, RRID:CVCL_6773 Copy
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