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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_U985
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Group: Patented cell line.
Proper citation: KCB Cat# KCB 2019022YJ, RRID:CVCL_U985 Copy
https://web.expasy.org/cellosaurus/CVCL_IM83
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB and AP-1-binding sites (InvivoGen=hkb-htlr5).
Proper citation: NCBI_Iran Cat# C634, RRID:CVCL_IM83 Copy
https://web.expasy.org/cellosaurus/CVCL_U985
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Group: Patented cell line.
Proper citation: Millipore Cat# SCC066, RRID:CVCL_U985 Copy
https://web.expasy.org/cellosaurus/CVCL_KU63
Organism: Homo sapiens (Human)
Category: Transformed cell line
Proper citation: DiscoverX Cat# 95-1024C1, RRID:CVCL_KU63 Copy
https://web.expasy.org/cellosaurus/CVCL_0288
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: DSMZ Cat# ACC-780, RRID:CVCL_0288 Copy
https://web.expasy.org/cellosaurus/CVCL_0045
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Biotechnology: Used for the production of the Gamaleya SARS-CoV-2 (COVID-19) vaccine (Trade name: Gam-COVID-Vac; also known as Sputnik V) (DrugBank=DB15848). Cautio., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 3., Group: Vaccine production cell line.
Proper citation: BEI_Resources Cat# ARP-103, RRID:CVCL_0045 Copy
https://web.expasy.org/cellosaurus/CVCL_HB82
Organism: Homo sapiens (Human)
Category: Transformed cell line
Proper citation: Kerafast Cat# EUR030, RRID:CVCL_HB82 Copy
https://web.expasy.org/cellosaurus/CVCL_0288
Organism: Mus musculus (Mouse)
Category: Spontaneously immortalized cell line
Proper citation: CLS Cat# 305050, RRID:CVCL_0288 Copy
https://web.expasy.org/cellosaurus/CVCL_AQ26
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: Responds to activation of the canonical Wnt signaling pathway by increasing expression of firefly luciferase. Luciferase reporter gene expression is under the control of a promoter with 7 LEF/TCF binding sites (PubMed=15035989).
Proper citation: ATCC Cat# CRL-3249, RRID:CVCL_AQ26 Copy
https://web.expasy.org/cellosaurus/CVCL_0045
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Biotechnology: Used for the production of the Gamaleya SARS-CoV-2 (COVID-19) vaccine (Trade name: Gam-COVID-Vac; also known as Sputnik V) (DrugBank=DB15848). Cautio., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 3., Group: Vaccine production cell line.
Proper citation: Ubigene Cat# YC-A008, RRID:CVCL_0045 Copy
https://web.expasy.org/cellosaurus/CVCL_S549
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Expression of the luciferase gene is under the control of a xenobiotic-responsive element (XRE) driven by a TATA promoter. HeB5 can be used for detection of mouse CYP1A induction by chemicals (ECACC=11033104)., Characteristics: Can be used for detection of mouse Cyp1a induction by chemicals (ECACC=11033104).
Proper citation: ECACC Cat# 11033104, RRID:CVCL_S549 Copy
https://web.expasy.org/cellosaurus/CVCL_A7YM
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of an IL12 p40 minimal promoter fused to 5 NF-kappaB and AP-1-binding sites (InvivoGen=hkb-null2).
Proper citation: NCBI_Iran Cat# C636, RRID:CVCL_A7YM Copy
https://web.expasy.org/cellosaurus/CVCL_U985
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Group: Patented cell line.
Proper citation: Ubigene Cat# YC-C029, RRID:CVCL_U985 Copy
https://web.expasy.org/cellosaurus/CVCL_A7UK
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: Expresses ACE2 under the control of the EF1a promoter (BEI_Resources=NR-52511)., Group: SARS-CoV-2 research cell line.
Proper citation: BEI_Resources Cat# NR-52511, RRID:CVCL_A7UK Copy
https://web.expasy.org/cellosaurus/CVCL_YI91
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: The red cAMP-Nomad biosensor consists of a membrane localization peptide derived from interleukin-2 receptor alpha chain, a TurboFP650 fluorescent protein, a Ht31 peptide fused to a KDEL signal., Characteristics: In absence of cAMP, the fluorescent biosensor is localized in the cellular membrane. An increase in this second messenger concentration leads to change in the structural folding of Nomad biosensor that promotes its cellular relocation in the vesicular trafficking of the cells.
Proper citation: Innoprot Cat# P70527, RRID:CVCL_YI91 Copy
https://web.expasy.org/cellosaurus/CVCL_XX01
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16., Characteristics: Transfected with the hprtDR-GFP reporter construct that targets the DR-GFP into the hprt locus and includes a dominant selectable puroR marker. The DR-GFP construct which contains a tandem repeat of two inactive genes coding for EGFP. After transfection with an expression vector coding for the I-SceI enzyme, recombination induced by the cleavage of the I-SceI site recreates a functional EGFP.
Proper citation: DSMZ Cat# ACC-845, RRID:CVCL_XX01 Copy
https://web.expasy.org/cellosaurus/CVCL_0063
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Virology: Highly susceptible to infection by Zika virus (ZIKV) (PubMed=29468137)., Part of: MD Anderson Cell Lines Project., Part of: ENCODE project common cell types; tier 3.
Proper citation: Abcam Cat# ab282205, RRID:CVCL_0063 Copy
https://web.expasy.org/cellosaurus/CVCL_W347
Organism: Homo sapiens (Human)
Category: Transformed cell line
Proper citation: ECACC Cat# 14050801, RRID:CVCL_W347 Copy
https://web.expasy.org/cellosaurus/CVCL_0063
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Virology: Highly susceptible to infection by Zika virus (ZIKV) (PubMed=29468137)., Part of: MD Anderson Cell Lines Project., Part of: ENCODE project common cell types; tier 3.
Proper citation: ICLC Cat# HTL04001, RRID:CVCL_0063 Copy
https://web.expasy.org/cellosaurus/CVCL_1926
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Group: Patented cell line.
Proper citation: ATCC Cat# CRL-11268, RRID:CVCL_1926 Copy
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