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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Discontinued
https://web.expasy.org/cellosaurus/CVCL_1065
Organism: Homo sapiens (Human)
Disease: Renal cell carcinoma
Category: Cancer cell line
Comments: Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1065 Copy
https://web.expasy.org/cellosaurus/CVCL_1059
Organism: Homo sapiens (Human)
Disease: Amelanotic melanoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Part of: BRAF genetic alteration cell panel (ATCC TCP-1032).
Proper citation: RRID:CVCL_1059 Copy
https://web.expasy.org/cellosaurus/CVCL_1062
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1062 Copy
https://web.expasy.org/cellosaurus/CVCL_M605
Organism: Homo sapiens (Human)
Disease: Chondrosarcoma
Category: Cancer cell line
Comments: Miscellaneous: STR profile established at MicroSynth from personal communication of Muff, Roman.
Proper citation: RRID:CVCL_M605 Copy
https://web.expasy.org/cellosaurus/CVCL_1046
Organism: Homo sapiens (Human)
Disease: Gastric adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1046 Copy
Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_1067
Organism: Homo sapiens (Human)
Disease: Papillary renal cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: NCI-60 cancer cell line panel., Part of: MD Anderson Cell Lines Project., Part of: JFCR39 cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1067 Copy
https://web.expasy.org/cellosaurus/CVCL_1066
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1066 Copy
Misidentified Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_4362
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Karyotypic information: Near triploid with the modal number of 67 chromosomes (ATCC=HTB-124)., Virology: Contains 2 copies of the SV40 genome, one complete the other incomplete tandemly integrated in the cell line genome., Part of: JWGray breast cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (PubMed=16643607; PubMed=20143388). Originally thought to originate from a casein-producing breast cell line from a 27 year old Caucasian woman. In addition contains SV40 genomic sequence while the cell line was deemed to be spontaneously immortalized..
Proper citation: Ubigene Cat# YC-C013, RRID:CVCL_4362 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0030
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: HeLa is the most frequent contributor to cell lines contamination., Anecdotal: Was flown since the 1960s on at least ten different space missions: Korabl-Sputnik-2, Vostok-1, Vostok-4, Vostok-5 and Vostok-6, Voshkod 1 and Zond-5, Discoverer XVIII, Progress M-35/Mir and Shuttle STS-89., Anecdotal: The HeLa cell line and its story inspired Australian artist Cynthia Verspaget to embark in 2003 on a artistic project 'The Anarchy Cell Line' (TAnCL) where she mixed her blood with HeLa cells. This work later spawned a PhD thesis (CelloPub=CLPUB00376) where among other things she makes the observation that two main taxonomical distinctions present in the zombie, living/dead and human/nonhuman, are also present in the HeLa cell line., Anecdotal: The fascinating story of the HeLa cell line and of Henrietta Lacks from whom these cells originate are described in the book of Rebecca Skloot (CelloPub=CLPUB00377)., Anecdotal: The HeLa cell line which was established in February 1951 is the oldest human immortal cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: HeLa has 5 five HPV18 integration sites: three on normal chromosomes 8 at 8q24 and two on derivative chromosomes, der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22) (q24;q13)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Proper citation: Ubigene Cat# YC-A012, RRID:CVCL_0030 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0030
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: HeLa is the most frequent contributor to cell lines contamination., Anecdotal: Was flown since the 1960s on at least ten different space missions: Korabl-Sputnik-2, Vostok-1, Vostok-4, Vostok-5 and Vostok-6, Voshkod 1 and Zond-5, Discoverer XVIII, Progress M-35/Mir and Shuttle STS-89., Anecdotal: The HeLa cell line and its story inspired Australian artist Cynthia Verspaget to embark in 2003 on a artistic project 'The Anarchy Cell Line' (TAnCL) where she mixed her blood with HeLa cells. This work later spawned a PhD thesis (CelloPub=CLPUB00376) where among other things she makes the observation that two main taxonomical distinctions present in the zombie, living/dead and human/nonhuman, are also present in the HeLa cell line., Anecdotal: The fascinating story of the HeLa cell line and of Henrietta Lacks from whom these cells originate are described in the book of Rebecca Skloot (CelloPub=CLPUB00377)., Anecdotal: The HeLa cell line which was established in February 1951 is the oldest human immortal cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: HeLa has 5 five HPV18 integration sites: three on normal chromosomes 8 at 8q24 and two on derivative chromosomes, der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22) (q24;q13)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Proper citation: BEI_Resources Cat# ARP-153, RRID:CVCL_0030 Copy
https://web.expasy.org/cellosaurus/CVCL_1806
Organism: Homo sapiens (Human)
Disease: Plasma cell myeloma
Category: Cancer cell line
Comments: Miscellaneous: HLA typing from personal communication of Pellat-Deceunynck, Catherine., Characteristics: Produces IgA kappa., Population: Japanese., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1806 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_1968
Organism: Homo sapiens (Human)
Disease: Prostate carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Problematic cell line: Contaminated. Shown to be a DU145 derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from a 67 year old man with a primary prostatic adenocarcinoma..
Proper citation: RRID:CVCL_1968 Copy
https://web.expasy.org/cellosaurus/CVCL_1244
Organism: Homo sapiens (Human)
Disease: Breast ductal carcinoma
Category: Cancer cell line
Comments: Miscellaneous: Direct author submission of STR profile from Girard, Luc & Gazdar, Adi F., Population: African American., Part of: JWGray breast cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: KCLB Cat# 9S1008, RRID:CVCL_1244 Copy
https://web.expasy.org/cellosaurus/CVCL_5310
Organism: Homo sapiens (Human)
Disease: Breast inflammatory carcinoma
Category: Cancer cell line
Comments: Characteristics: ER-negative, PR-negative and ERBB2-positive., Population: Japanese., Part of: JFCR45 cancer cell line panel.
Proper citation: CLS Cat# 305578, RRID:CVCL_5310 Copy
https://web.expasy.org/cellosaurus/CVCL_2866
Organism: Homo sapiens (Human)
Disease: Nevoid basal cell carcinoma syndrome
Category: Finite cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_2866 Copy
https://web.expasy.org/cellosaurus/CVCL_0152
Organism: Homo sapiens (Human)
Disease: Pancreatic ductal adenocarcinoma
Category: Cancer cell line
Comments: Caution: TP53 mutation indicated incorrectly as being at c.818G>A in PubMed=1630814., Population: Caucasian., Part of: NCI RAS program mutant KRAS cell line panel., Part of: MD Anderson Cell Lines Project., Part of: KuDOS 95 cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0152 Copy
https://web.expasy.org/cellosaurus/CVCL_2299
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: One copy of the ATR gene has been disrupted while lox sites have been added flanking exon 2 of the 2nd allele thus making it susceptible to Cre-mediated deletion., Population: Caucasian.
Proper citation: RRID:CVCL_2299 Copy
https://web.expasy.org/cellosaurus/CVCL_0153
Organism: Homo sapiens (Human)
Disease: Poorly differentiated thyroid gland carcinoma
Category: Cancer cell line
Comments: Caution: Originally classified a thyroid gland papillary carcinoma (PTC) but is now considered to be a poorly differentiated thyroid gland carcinoma (PDTC) (PubMed=23162534)., Population: Caucasian., Part of: TCGA-110-CL cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0153 Copy
https://web.expasy.org/cellosaurus/CVCL_0168
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Part of: Small cell lung cancer p53 hotspot mutation cell panel (ATCC TCP-2040)., Group: Patented cell line.
Proper citation: AddexBio Cat# T0007001/26, RRID:CVCL_0168 Copy
https://web.expasy.org/cellosaurus/CVCL_1082
Organism: Homo sapiens (Human)
Disease: Lung non-small cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1082 Copy
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