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Species: Homo sapiens
Genetic Insert: GAlphaz-Rluc8
Vector Backbone Description: Backbone Marker:Invitrogen; Backbone Size:5203; Vector Backbone:pcDNA5/FRT/TO; Vector Types:Mammalian Expression, Luciferase; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32367019
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_140978 Copy
Species: Halothiobacillus neapolitanus
Genetic Insert: CbbL, CbbS, CsoS2 (delN1-N3), CsoSCA, CsoS4A, CsoS4B, CsoS1C, CsoS1A, CsoS1B, CsoS1D
Vector Backbone Description: Backbone Size:4891; Vector Backbone:NS3; Vector Types:Bacterial Expression; Bacterial Resistance:Chloramphenicol
Defining Citation: PMID:32123388
Proper citation: RRID:Addgene_140858 Copy
Species: Homo sapiens
Genetic Insert: GAlphaGustducin-RLuc8
Vector Backbone Description: Backbone Marker:Invitrogen; Backbone Size:5134; Vector Backbone:pcDNA5/FRT/TO; Vector Types:Mammalian Expression, Luciferase; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32367019
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_140979 Copy
Species: Halothiobacillus neapolitanus
Genetic Insert: CbbL, CbbS, CsoS2 (delN1-N2, N4), CsoSCA, CsoS4A, CsoS4B, CsoS1C, CsoS1A, CsoS1B, CsoS1D
Vector Backbone Description: Backbone Size:4891; Vector Backbone:NS3; Vector Types:Bacterial Expression; Bacterial Resistance:Chloramphenicol
Defining Citation: PMID:32123388
Proper citation: RRID:Addgene_140859 Copy
Genetic Insert: CsoS2 NTD repeat 2 fused to GFP
Vector Backbone Description: Backbone Marker:Novagen; Backbone Size:4614; Vector Backbone:pET-14b; Vector Types:Bacterial Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32123388
Proper citation: RRID:Addgene_140853 Copy
Species: Homo sapiens
Genetic Insert: GAlphai3-RLuc8
Vector Backbone Description: Backbone Marker:Invitrogen; Backbone Size:5189; Vector Backbone:pcDNA5/FRT/TO; Vector Types:Mammalian Expression, Luciferase; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32367019
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_140975 Copy
Species: Halothiobacillus neapolitanus
Genetic Insert: CbbL, CbbS, CsoS2 (delNTD), CsoSCA, CsoS4A, CsoS4B, CsoS1C, CsoS1A, CsoS1B, CsoS1D
Vector Backbone Description: Backbone Size:4891; Vector Backbone:NS3; Vector Types:Bacterial Expression; Bacterial Resistance:Chloramphenicol
Defining Citation: PMID:32123388
Proper citation: RRID:Addgene_140860 Copy
Genetic Insert: CsoS2 NTD fused to GFP
Vector Backbone Description: Backbone Marker:Novagen; Backbone Size:4614; Vector Backbone:pET-14b; Vector Types:Bacterial Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32123388
Proper citation: RRID:Addgene_140861 Copy
Species: Homo sapiens
Genetic Insert: GAlphaQ-RLuc8
Vector Backbone Description: Backbone Marker:Invitrogen; Backbone Size:5189; Vector Backbone:pcDNA5/FRT/TO; Vector Types:Mammalian Expression, Luciferase; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32367019
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_140982 Copy
Species: Homo sapiens
Genetic Insert: PTPN11 protein tyrosine phosphatase non-receptor type 11 [ Homo sapiens (human) ]
Vector Backbone Description: Backbone Size:10065; Vector Backbone:pLX307; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:31771968
Proper citation: RRID:Addgene_140862 Copy
Species: Homo sapiens
Genetic Insert: GAlpha11-RLuc8
Vector Backbone Description: Backbone Marker:Invitrogen; Backbone Size:5203; Vector Backbone:pcDNA5/FRT/TO; Vector Types:Mammalian Expression, Luciferase; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32367019
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_140983 Copy
Species: Mus musculus
Genetic Insert: PI3K catalytic subunit p110alpha-Myc- (iSH2-p85alpha)
Vector Backbone Description: Backbone Size:4700; Vector Backbone:pSRalpha; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Comments: Please note that NcoI is not a unique enzyme and will cut the plasmid DNA at five locations.
Proper citation: RRID:Addgene_1410 Copy
Genetic Insert: PCP-Mxi1
Vector Backbone Description: Backbone Size:4300; Vector Backbone:pCfB3035; Vector Types:; Bacterial Resistance:Ampicillin
Defining Citation: PMID:28298224
Proper citation: RRID:Addgene_140904 Copy
Species: Danio rerio
Genetic Insert: zebrafish smyhc1_977 sgRNA for in vitro transcription
Vector Backbone Description: Vector Backbone:pT7gRNA-ccdb (Addgene 140864); Vector Types:In vitro transcription of sgRNAs; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32709891
Proper citation: RRID:Addgene_140867 Copy
Species: Synthetic
Genetic Insert: SpiCee-NLS
Vector Backbone Description: Vector Backbone:pCX; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32697983
Proper citation: RRID:Addgene_140900 Copy
Species: Synthetic
Genetic Insert: TetR-sfGFP expressed with T7 promoter
Vector Backbone Description: Backbone Marker:Promega; Vector Backbone:pTNT; Vector Types:Bacterial Expression, Synthetic Biology; Bacterial Resistance:Ampicillin
Defining Citation: PMID:30487584
Proper citation: RRID:Addgene_140868 Copy
Species: Homo sapiens
Genetic Insert: GGamma1-GFP2
Vector Backbone Description: Backbone Marker:Invitrogen; Backbone Size:5432; Vector Backbone:pcDNA3.1; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32367019
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_140989 Copy
Species: Synthetic
Genetic Insert: mutSpiCee
Vector Backbone Description: Vector Backbone:pCX; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32697983
Proper citation: RRID:Addgene_140903 Copy
Species: Homo sapiens
Genetic Insert: GAlpha12-RLuc8
Vector Backbone Description: Backbone Marker:Invitrogen; Backbone Size:5203; Vector Backbone:pcDNA5/FRT/TO; Vector Types:Mammalian Expression, Luciferase; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32367019
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_140985 Copy
Species: Homo sapiens
Genetic Insert: GAlpha13-RLuc8
Vector Backbone Description: Backbone Marker:Invitrogen; Backbone Size:5203; Vector Backbone:pcDNA5/FRT/TO; Vector Types:Mammalian Expression, Luciferase; Bacterial Resistance:Ampicillin
Defining Citation: PMID:32367019
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_140986 Copy
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