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Species: Homo sapiens
Genetic Insert: AP-4 complex subunit epsilon-1
Vector Backbone Description: Vector Backbone:pRK5; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:31142229
Proper citation: RRID:Addgene_127624 Copy
Species: Homo sapiens
Genetic Insert: Miro1
Vector Backbone Description: Vector Backbone:pEGFP-C1; Vector Types:Mammalian Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:31894645
Proper citation: RRID:Addgene_127628 Copy
Species: Homo sapiens
Genetic Insert: Miro1
Vector Backbone Description: Vector Backbone:pEGFP-C1; Vector Types:Mammalian Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:31894645
Proper citation: RRID:Addgene_127626 Copy
Genetic Insert: GABA-A receptor subunit gamma-2
Vector Backbone Description: Vector Backbone:pRK5; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:19815531
Proper citation: RRID:Addgene_127619 Copy
Genetic Insert: Sindbis Glycoproteins
Vector Backbone Description: Vector Backbone:pSin; Vector Types:Synthetic Biology; Bacterial Resistance:Ampicillin
Defining Citation: PMID:31280962
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_127694 Copy
Genetic Insert: Sindbis Capsid
Vector Backbone Description: Vector Backbone:pSin; Vector Types:Synthetic Biology; Bacterial Resistance:Ampicillin
Defining Citation: PMID:31280962
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_127693 Copy
Genetic Insert: Sindbis Structural Genome
Vector Backbone Description: Vector Backbone:pSRE; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:31280962
Comments: These plasmids were generated as part of the Illuminating the Druggable Genome (IDG) program sponsored by the NIH Common Fund. The goal of this program is to identify, gather, and distribute information and resources for proteins that currently are not well-studied yet belong to commonly drug-targeted protein families: protein kinases, non-olfactory G-protein coupled receptors (GPCRs), and ion channels. The IDG program is designed to develop fundamental research tools for understudied proteins, elucidate their function, and disseminate the IDG-related resources and data to the greater scientific community.
Proper citation: RRID:Addgene_127692 Copy
Species: Mus musculus
Genetic Insert: shSTING Mmu
Vector Backbone Description: Backbone Size:13320; Vector Backbone:pTRIPZ RFP+; Vector Types:Mammalian Expression, Lentiviral; Bacterial Resistance:Ampicillin
Defining Citation: PMID:28598415
Proper citation: RRID:Addgene_127697 Copy
Species: Homo sapiens
Genetic Insert: shNS
Vector Backbone Description: Backbone Size:13320; Vector Backbone:pTRIPZ RFP+; Vector Types:Mammalian Expression, Lentiviral; Bacterial Resistance:Ampicillin
Defining Citation: PMID:28598415
Proper citation: RRID:Addgene_127696 Copy
Species: Mus musculus
Genetic Insert: shIFNAR1 Mmu
Vector Backbone Description: Backbone Size:13320; Vector Backbone:pTRIPZ RFP+; Vector Types:Mammalian Expression, Lentiviral; Bacterial Resistance:Ampicillin
Defining Citation: PMID:28598415
Proper citation: RRID:Addgene_127699 Copy
Species: Mus musculus
Genetic Insert: KIF5C
Vector Backbone Description: Vector Backbone:pRK5; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:20152113
Proper citation: RRID:Addgene_127618 Copy
Species: Synthetic
Genetic Insert: cis-aconitate decarboxylase
Vector Backbone Description: Vector Backbone:pDSM-bc; Vector Types:Yeast Expression, Synthetic Biology; Bacterial Resistance:Kanamycin
Defining Citation: PMID:29753070
Comments: CAD transcription unit with pathway position 3 homology arms, compatible with 5' position 2 and 3' position 3 homology arm. Sequencing primers are also the primers for amplifying DNA for integration into the S. cerevisiae genome.
Proper citation: RRID:Addgene_127729 Copy
Species: Synthetic
Genetic Insert: cis-aconitate decarboxylase
Vector Backbone Description: Vector Backbone:pDSM-bc; Vector Types:Yeast Expression, Synthetic Biology; Bacterial Resistance:Kanamycin
Defining Citation: PMID:29753070
Comments: CAD transcription unit with pathway position 3 homology arms, compatible with 5' position 2 and 3' position 3 homology arm. Sequencing primers are also the primers for amplifying DNA for integration into the S. cerevisiae genome.
Proper citation: RRID:Addgene_127728 Copy
Species: Aspergillus terreus
Genetic Insert: cis-aconitate decarboxylase
Vector Backbone Description: Vector Backbone:pDSM-bc; Vector Types:Yeast Expression, Synthetic Biology; Bacterial Resistance:Kanamycin
Defining Citation: PMID:29753070
Comments: CAD transcription unit with pathway position 3 homology arms, compatible with 5' position 2 and 3' position 3 homology arm. Sequencing primers are also the primers for amplifying DNA for integration into the S. cerevisiae genome.
Proper citation: RRID:Addgene_127727 Copy
Species: Aspergillus terreus
Genetic Insert: itaconate transporter from A. terreus
Vector Backbone Description: Vector Backbone:pDSM-5a; Vector Types:Yeast Expression, Synthetic Biology; Bacterial Resistance:Kanamycin
Defining Citation: PMID:29753070
Comments: ITE transcription unit with pathway position 1 homology arms, compatible with 5' ChrXV homology arm (5int) and 3' position 2 homology arm. Sequencing primers are also the primers for amplifying DNA for integration into the S. cerevisiae genome.
Proper citation: RRID:Addgene_127725 Copy
Vector Backbone Description: Vector Backbone:pDSM; Vector Types:Synthetic Biology; Bacterial Resistance:Kanamycin
Defining Citation: PMID:29753070
Comments: Assembles a transcription unit and adds pathway position 4 homology arms, compatible with 5' position 3 and 3' position 5 homology arm. Ccdb selection is used to select for correct clones. Sequencing primers are also the primers for amplifying DNA for integration into the S. cerevisiae genome.
Proper citation: RRID:Addgene_127719 Copy
Species: Escherichia coli
Genetic Insert: ygiF-CHAD
Vector Backbone Description: Backbone Marker:Michael Hothorn; Backbone Size:5320; Vector Backbone:pMH-HT; Vector Types:Bacterial Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:31133615
Proper citation: RRID:Addgene_127793 Copy
Species: Chlorobium tepidum
Genetic Insert: CtCHAD
Vector Backbone Description: Backbone Marker:Michael Hothorn; Backbone Size:5311; Vector Backbone:pMH-HT; Vector Types:Bacterial Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:31133615
Proper citation: RRID:Addgene_127791 Copy
Species: Chlorobium tepidum
Genetic Insert: CtCHAD
Vector Backbone Description: Backbone Marker:Michael Hothorn; Backbone Size:5311; Vector Backbone:pMH-HT; Vector Types:Bacterial Expression; Bacterial Resistance:Kanamycin
Defining Citation: PMID:31133615
Proper citation: RRID:Addgene_127790 Copy
Species: firefly
Genetic Insert: destabilized mutant (DM) Luciferase
Vector Backbone Description: Backbone Size:4600; Vector Backbone:pRK5; Vector Types:Mammalian Expression; Bacterial Resistance:Ampicillin
Defining Citation: PMID:27684355
Proper citation: RRID:Addgene_127796 Copy
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