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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://sourceforge.net/projects/netclassr/
An R package for network-based feature (gene) selection for biomarkers discovery via integrating biological information. The package adapts the following 5 algorithms for classifying and predicting gene expression data using prior knowledge: # average gene expression of pathway (aep); # pathway activities classification (PAC); # Hub network classification (hubc); # filter via top ranked genes (FrSVM); # network smoothed t-statistic (stSVM).
Proper citation: netClass (RRID:SCR_005672) Copy
http://www.bioconductor.org/packages/devel/bioc/html/DMRforPairs.html
Software for identifying differentially methylated regions between unique samples using array based methylation profiles. It allows researchers to compare n greater than or equal to 2 unique samples with regard to their methylation profile. The (pairwise) comparison of n unique single samples distinguishesit from other existing pipelines as these often compare groups of samples in either single CpG locus or region based analysis. DMRforPairs defines regions of interest as genomic ranges with sufficient probes located in close proximity to each other. Probes in one region are optionally annotated to the same functional class(es). Differential methylation is evaluated by comparing the methylation values within each region between individual samples and (if the difference is sufficiently large), testing this difference formally for statistical significance.
Proper citation: DMRforPairs (RRID:SCR_005702) Copy
http://www.vicbioinformatics.com/software.vague.shtml
An open-source de novo genome assembly software tool, which is run from the Unix command line, providing a multi-platform graphical front-end for the Velvet de novo assembler. VAGUE is implemented in JRuby and targets the Java Virtual Machine.
Proper citation: VAGUE (RRID:SCR_005607) Copy
http://www.bioinformatics.babraham.ac.uk/projects/bismark/
Software tool to map bisulfite converted sequence reads and determine cytosine methylation states. Flexible aligner and methylation caller for Bisulfite-Seq applications. Used to map bisulfite treated sequencing reads to genome of interest and perform methylation calls in single step.
Proper citation: Bismark (RRID:SCR_005604) Copy
https://code.google.com/p/jmhc/
Software for analyzing and visualization of the results of deep amplicon sequencing.
Proper citation: jMHC (RRID:SCR_005605) Copy
http://genome-www.stanford.edu/TMA/combiner/
A Simple Software Tool to Permit Analysis of Replicate Cores on Tissue Microarrays., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: TMA-Combiner (RRID:SCR_005600) Copy
http://tmaj.pathology.jhmi.edu/
Open-source software to support information and images related to tissue micro-arrays. It contains support for multiple organ systems, multiple users, image analysis, and is designed to be compliant with HIPPA regulations. Patients, specimens, blocks, slides, cores, images, and scores can all be stored and viewed. Features include advanced security, custom dynamic fields, and an image analysis program.
Proper citation: TMAJ (RRID:SCR_005601) Copy
http://agbase.msstate.edu/cgi-bin/tools/goprofiler_select.pl
Service that provides a summary of GO annotations available for each species. The user provides a taxon id and GOProfiler displays the number of GO associations and the number of annotated proteins for that species. The results are listed by evidence code and a separate list of unannotated proteins is also provided.
Proper citation: GOProfiler (RRID:SCR_005683) Copy
http://genome-www.stanford.edu/TMA/
Software Tools for High-Throughput Analysis and Archiving of Immunohistochemistry Staining Data Obtained with Tissue Microarrays.
Proper citation: Stanford TMA Software (RRID:SCR_005598) Copy
http://www.compbio.dundee.ac.uk/downloads/oxbench/
A suite of programs aimed at developers of alignment methods rather than end-users to assess the accuracy of multiple sequence alignment methods. It includes a reference database of protein multiple sequence alignments that were generated by consideration of protein three-dimensional structure.
Proper citation: OXBench (RRID:SCR_005591) Copy
http://staden.sourceforge.net/
A fully developed set of DNA sequence assembly (Gap4 and Gap5), editing and analysis tools (Spin) for Unix, Linux, MacOSX and MS Windows.
Proper citation: Staden Package (RRID:SCR_005629) Copy
http://mesquiteproject.org/packages/chromaseq/
A software package in Mesquite that processes chromatograms, makes contigs, base calls, etc., using in part the programs Phred and Phrap.
Proper citation: Chromaseq (RRID:SCR_005587) Copy
https://github.com/phe-bioinformatics/snp-search/tree/master/test_data
A software tool that manages SNP data and outputs useful information which can be used to test important biological hypotheses.
Proper citation: snp-search (RRID:SCR_005618) Copy
http://sourceforge.net/projects/dical-ibd/
Software tool for detecting identity-by-descent (IBD) tracts between pairs of genomic sequences.
Proper citation: diCal-IBD (RRID:SCR_012111) Copy
http://sourceforge.net/projects/ionwinze/
Software tool to pick out ion signals that discriminate two groups of samples (e.g. diseased/healthy, resistant/susceptible) by quasi-datapoint-wise comparison using univariate statistic procedures.
Proper citation: Ionwinze (RRID:SCR_012115) Copy
http://sourceforge.net/projects/genosight/
An adaptive imaging cytometry software environment.
Proper citation: GenoSIGHT (RRID:SCR_012119) Copy
https://github.com/stoeckli/MSImageViewer
Software for the conversion of data acquired with the FlashQuant (MALDI version of ABSciex 4000) into MS images.
Proper citation: MSImageViewer (RRID:SCR_012121) Copy
https://code.google.com/p/cell-motility/
An open source Java application that provides a clear and concise analysis workbench for large amounts of cell motion data.
Proper citation: Cell motility (RRID:SCR_012120) Copy
https://code.google.com/p/glycanbuilder/
An intuitive and flexible software tool for building and displaying glycan structures.
Proper citation: GlycanBuilder (RRID:SCR_012123) Copy
https://code.google.com/p/glycresoft/
A software package for automated recognition of glycans from LC/MS data.
Proper citation: GlycReSoft (RRID:SCR_012122) Copy
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