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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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tfcheckpoint Resource Report Resource Website 1+ mentions |
tfcheckpoint (RRID:SCR_023880) | data or information resource, database | Collection of transcription factors annotated according to experimental and other evidence on their function as true DbTFs. Provides reference for both small scale experiments and genome scale studies. Curated compendium of specific DNA-binding RNA polymerase II transcription factors. | transcription factor, DNA-binding RNA polymerase II transcription factors, DNA-binding, RNA polymerase II transcription factors, | Liaison Committee between the Central Norway Regional Health Authority ; Norwegian Cancer Society ; Norwegian University of Science and Technology |
PMID:23933972 | Free, Freely available | SCR_023880 | 2026-09-12 01:02:22 | 4 | |||||||||
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Kravitz Dataset 2 Resource Report Resource Website 1+ mentions |
Kravitz Dataset 2 (RRID:SCR_000296) | data or information resource, data set | Dataset of the spike and laser timestamps from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings." The code will analyze spike trains around laser pulses to determine if a cell is significantly activated by the laser, and therefore expresses an excitatory opsin, such as channelrhodopsin-2. It returns an excel sheet that simply identifies the activated cells. | data set, neuron, spike train, optogenetic, in vivo, laser, channelrhodopsin, matlab | has parent organization: University of California at San Francisco; California; USA | Addiction, Parkinson's disease, Tourette's syndrome | PMID:23178332 | nlx_151410 | SCR_000296 | 2026-09-12 01:03:09 | 1 | ||||||||
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Center for In Vivo Microscopy Resource Report Resource Website 10+ mentions |
Center for In Vivo Microscopy (RRID:SCR_001426) | CIVM | biomedical technology research center, training resource | Biomedical technology research center dedicated to the development of novel imaging methods for the basic scientist and the application of the methods to important biomedical questions. The CIVM has played a major role in the development of magnetic resonance microscopy with specialized MR imaging systems capable of imaging at more than 500,000x higher resolution than is common in the clinical domain. The CIVM was the first to demonstrate MR images using hyperpolarized 3He which has been moved from mouse to man with recent clinical trials performed at Duke in collaboration with GE. More recently the CIVM has developed the molecular imaging workbench---a system dedicated to multimodality cardiopulmonary imaging in the rodent. Their collaborators are employing these unique imaging systems in an extraordinary range of mouse and rat models of neurologic disease, cardiopulmonary disease and cancer to illuminate the underlying biology and explore new therapies. | imaging, magnetic resonance microscopy, magnetic resonance imaging, clinical, mri, ct, x-ray, ultrasound, confocal, optical, spect | has parent organization: Duke University; North Carolina; USA | Cardiopulmonary disease, Cancer, Neurological disease | NIBIB 4P41EB015897-27 | Free, Freely Available | nlx_152650 | SCR_001426 | Duke Center for In Vivo Microscopy | 2026-09-12 01:03:11 | 10 | |||||
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Mammalian Brain Methylomes Resource Report Resource Website |
Mammalian Brain Methylomes (RRID:SCR_001648) | Mammalian Brain Methylomes | data or information resource, data set | THIS RESOURCE IS NO LONGER IN SERVICE. Datasets described in the manuscript: "Global Epigenomic Reconfiguration During Mammalian Brain Development" (Science, 2013 - DOI: 10.1126/science.1237905. This study provides genome-wide composition, patterning, cell specificity, and dynamics of DNA methylation at single-base resolution in human and mouse frontal cortex throughout their lifespan. Widespread methylome reconfiguration occurs during fetal to young adult development, coincident with synaptogenesis. | epigenetics, methylation, frontal cortex, development, neuron, methylome, maturation, learning, young adult, fetus | has parent organization: Salk Institute for Biological Studies | PMID:23828890 | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_153926 | SCR_001648 | Mammalian Brain Methylomes | 2026-09-12 01:03:12 | 0 | ||||||
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Connectomic reconstruction of the inner plexiform layer in the mouse retina Resource Report Resource Website 1+ mentions |
Connectomic reconstruction of the inner plexiform layer in the mouse retina (RRID:SCR_002246) | MPIN Connectomics | data or information resource, data set | Data set of the dense reconstruction of 950 neurons and their mutual contacts for the mouse inner plexiform layer--the main computational neuropil region in the mammalian retina. This was achieved by applying a combination of crowd-sourced manual annotation and machine-learning-based volume segmentation to serial block-face electron microscopy data. They characterize a new type of retinal bipolar interneuron and show that they can subdivide a known type based on connectivity. Circuit motifs that emerge from their data indicate a functional mechanism for a known cellular response in a ganglion cell that detects localized motion, and predict that another ganglion cell is motion sensitive. A Data browser is also available for download | connectome, retina, retina inner plexiform layer | has parent organization: Max Planck Institute for Biological Intelligence | Max-Planck-Gesellschaft ; DFG ; Gatsby Charitable Foundation |
PMID:23925239 | Free, Freely available | nlx_155563 | SCR_002246 | 2026-09-12 01:03:12 | 1 | ||||||
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EID: Exon-Intron Database Resource Report Resource Website 10+ mentions |
EID: Exon-Intron Database (RRID:SCR_002469) | EID | data or information resource, data set | Data sets of protein-coding intron-containing genes that contain gene information from humans, mice, rats, and other eukaryotes, as well as genes from species whose genomes have not been completely sequenced. This is a comprehensive and convenient dataset of sequences for computational biologists who study exon-intron gene structures and pre-mRNA splicing. The database is derived from GenBank release 112, and it contains protein-coding genes that harbor introns, along with extensive descriptions of each gene and its DNA and protein sequences, as well as splice motif information. They have created subdatabases of genes whose intron positions have been experimentally determined. The collection also contains data on untranslated regions of gene sequences and intron-less genes. For species with entirely sequenced genomes, species-specific databases have been generated. A novel Mammalian Orthologous Intron Database (MOID) has been introduced which includes the full set of introns that come from orthologous genes that have the same positions relative to the reading frames. | eukaryote genome, exon, exon-intro, gene structure, genome splicing, intron, ortholog, fasta, gene, protein-coding gene, splice, motif, gene prediction, structure, coding region |
is listed by: OMICtools has parent organization: University of Toledo; Ohio; USA |
PMID:16772261 PMID:10592221 |
Free, Available for download, Freely available | OMICS_01886, nif-0000-02793 | http://www.utoledo.edu/med/depts/bioinfo/database.html | http://www.meduohio.edu/bioinfo/eid/, http://mcb.harvard.edu/gilbert/EID | SCR_002469 | The Exon-Intron Database, Exon-Intron Database | 2026-09-12 01:03:13 | 11 | ||||
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MMPC-University of Michigan Medical School Animal Care and Germ-Free Mouse Core Resource Report Resource Website |
MMPC-University of Michigan Medical School Animal Care and Germ-Free Mouse Core (RRID:SCR_015344) | access service resource, core facility, resource, service resource | Core that provides services to the University of Michigan community and can also ship germ-free mice to locations worldwide. Its projects include studies investigating inflammatory bowel disease and cancer, host microbiome interactions, infectious disease pathogenesis, and mammalian and bacterial metabolism. | animal care, germ-free mouse care |
is listed by: NIDDK Information Network (dkNET) has parent organization: National Mouse Metabolic Phenotyping Centers has parent organization: University of Michigan; Ann Arbor; USA has parent organization: MMPC-University of Michigan Medical School is organization facet of: MMPC-University of Michigan Medical School |
NIDDK U2C-DK110768 | Available to the research community, Fee for service, Users must have an approved animal use protocol from the Institutional Animal Care and Use Committee | SCR_015344 | 2026-09-12 01:03:55 | 0 | |||||||||
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Yale Cooperative Center of Excellence in Hematology Animal Modeling Core Resource Report Resource Website |
Yale Cooperative Center of Excellence in Hematology Animal Modeling Core (RRID:SCR_015349) | access service resource, core facility, resource, service resource | Core facility which provides expertise, technical assistance, and mice for human-into-mouse xenotransplantation studies. Mouse models include MITRG-SKI (KnockIn) mice that express human cytokines and huSIRPa from the endogenous murine loci in the Rag-/- IL-2Ry -/- background. It also offers training and technical assistance in the study of hematopoiesis and benign hematologic questions in mice. | mouse model, hematology mouse model, xenotransplantation, hematopoeisis model |
is listed by: NIDDK Information Network (dkNET) has parent organization: Yale School of Medicine; Connecticut; USA has parent organization: Yale Cooperative Center of Excellence in Hematology is organization facet of: Yale Cooperative Center of Excellence in Hematology |
NIDDK U54DK106857 | Available to the research community | SCR_015349 | 2026-09-12 01:03:55 | 0 | |||||||||
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Boston Children's Hospital Center of Excellence in Molecular Hematology Stem Cell Engineering and Analysis Core Resource Report Resource Website |
Boston Children's Hospital Center of Excellence in Molecular Hematology Stem Cell Engineering and Analysis Core (RRID:SCR_015352) | access service resource, core facility, resource, service resource | Core facility for basic and translational stem cell research. The core's areas of expertise include human pluripotent stem cell biology, cGMP cell manufacturing, reprogramming, genome editing, genotyping, laboratory automation, chemical screening, and imaging/image analysis. | basic stem cell research, translational stem cell research, stem cell core facility |
is listed by: NIDDK Information Network (dkNET) has parent organization: Boston Children's Hospital Center of Excellence in Molecular Hematology is organization facet of: Boston Children's Hospital Center of Excellence in Molecular Hematology |
NIDDK U54DK110805 | Available to the research community, Fee for service | SCR_015352 | 2026-09-12 01:03:55 | 0 | |||||||||
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MMPC-Vanderbilt University School of Medicine Cardiovascular Pathophysiology Core Resource Report Resource Website |
MMPC-Vanderbilt University School of Medicine Cardiovascular Pathophysiology Core (RRID:SCR_015353) | access service resource, core facility, service resource | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 6th,2023. Core whose objective is to provide investigators at Vanderbilt and outside institutions a means to accurately assess cardiovascular phenotypes in mouse models of diabetes and metabolic disease. The CPC uses validated approaches and state-of-the-art instrumentation that allow for sensitive screening of phenotypic variations. | cardiovascular phenotype, cardiovascular mouse model, diabetes mouse model, metabolic mouse model |
is listed by: NIDDK Information Network (dkNET) has parent organization: National Mouse Metabolic Phenotyping Centers has parent organization: MMPC-Vanderbilt University School of Medicine is organization facet of: MMPC-Vanderbilt University School of Medicine |
Diabetes, metabolic disease | NIDDK U24 DK059637 | THIS RESOURCE IS NO LONGER IN SERVICE | SCR_015353 | 2026-09-12 01:03:55 | 0 | ||||||||
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George M. O'Brien Kidney Center at Yale Mouse Genetics and Cell Line Core Resource Report Resource Website |
George M. O'Brien Kidney Center at Yale Mouse Genetics and Cell Line Core (RRID:SCR_015299) | access service resource, core facility, resource, service resource | Core provides services to generate unique in vivo mouse models and kidney specific cell lines. | mouse genetics, kidney cell lines, bacterial artificial chromosome |
is listed by: NIDDK Information Network (dkNET) has parent organization: Yale School of Medicine; Connecticut; USA has parent organization: George M. O'Brien Kidney Center at Yale is organization facet of: George M. O'Brien Kidney Center at Yale |
NIDDK P30DK079310 | Available to the research community | SCR_015299 | 2026-09-12 01:03:54 | 0 | |||||||||
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Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Mouse Models Core Resource Report Resource Website |
Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Mouse Models Core (RRID:SCR_015389) | access service resource, core facility, resource, service resource | Core that provides support and expertise for mouse colony maintenance, breeding strategies, mouse lung phenotyping protocols, and submission of live-animal applications to maintain compliance with IACUC guidelines. | mouse model, mouse maintanence, pathophysiology, treatment, pathology |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of North Carolina at Chapel Hill School of Medicine; North Carolina; USA has parent organization: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center is organization facet of: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center |
Cystic Fibrosis, pulmonary disease | North American Cystic Fibrosis Foundation ; NIDDK P30DK065988 |
Available to the research community | SCR_015389 | 2026-09-12 01:03:55 | 0 | ||||||||
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MMPC-Vanderbilt University School of Medicine Animal Health and Welfare Core Resource Report Resource Website |
MMPC-Vanderbilt University School of Medicine Animal Health and Welfare Core (RRID:SCR_015380) | access service resource, core facility, resource, service resource | Core that ensures the health and welfare of mouse models by assuring that mice admitted to the MMPC meet defined health criteria and that post-quarantine protocol assignment. It diagnoses disease and identifies unique metabolic or cardiovascular phenotypes of mice through interaction with the Comparative Pathology Subcore. | animal health, Animal care, quarantine, receipt of mice, approved vendors, testing of mice, animal husbandry, Core, animal, vendors, testing, husbandry |
is listed by: NIDDK Information Network (dkNET) has parent organization: National Mouse Metabolic Phenotyping Centers has parent organization: MMPC-Vanderbilt University School of Medicine is organization facet of: MMPC-Vanderbilt University School of Medicine |
NIDDK U24 DK059637 | Available to the research community | SCR_015380 | 2026-09-12 01:03:55 | 0 | |||||||||
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Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Animal Models Core Resource Report Resource Website |
Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Animal Models Core (RRID:SCR_015396) | access service resource, core facility, resource, service resource | Core that assists in mouse line generation by both oocyte micro-injection and by embryonic stem cell gene targeting technologies. It also establishes breeding colonies of cystic fibrosis mice, and genotypes and provides these to UAB investigators and furnishes electrophysiology tests of CFTR activation, including murine nasal potential difference assays and intestinal short circuit current measurements. | animal models, mouse model, mice colonies, cystic fibrosis research, cystic fibrosis model |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Alabama at Birmingham School of Medicine; Alabama; USA has parent organization: Gregory Fleming James Cystic Fibrosis Research Center is organization facet of: Gregory Fleming James Cystic Fibrosis Research Center |
Cystic Fibrosis | NIDDK P30DK072482; Cystic Fibrosis Foundation |
Available to the research community | SCR_015396 | 2026-09-12 01:03:56 | 0 | ||||||||
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MMPC-University of California Davis Energy Balance Exercise and Behavior Core Resource Report Resource Website 1+ mentions |
MMPC-University of California Davis Energy Balance Exercise and Behavior Core (RRID:SCR_015364) | access service resource, core facility, resource, service resource | Core that provides investigators with services to accurately measure the major components of energy balance in their mouse models and tests that allow investigators to examine physiological factors that may influence food intake or energy expenditure. | energy balance, exercise and behavior, obesity |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of California at Davis; California; USA has parent organization: National Mouse Metabolic Phenotyping Centers has parent organization: MMPC-University of California Davis is organization facet of: MMPC-University of California Davis |
Obesity, Diabetes, metabolic disease | NIDDK DK092993 | Available to the research community | SCR_015364 | 2026-09-12 01:03:55 | 6 | ||||||||
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MMPC-University of Massachusetts Medical School Metabolism Core Resource Report Resource Website |
MMPC-University of Massachusetts Medical School Metabolism Core (RRID:SCR_015369) | access service resource, core facility, resource, service resource | Core that conducts specialized and non-invasive metabolic experiments to measure insulin sensitivity, glucose/lipid/protein metabolism, pancreatic beta-cell function, body composition and energy balance. Its services include access to hyperglycemic clamps to assess insulin secretion and pancreatic beta cell function in awake mice and exercise studiesl with acute, chronic endurance, and exhaustive exercise protocols and using in-house cage wheels. | metabolism core, body composition, energy balance, exercise studies |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Massachusetts Medical School; Massachusetts; USA has parent organization: National Mouse Metabolic Phenotyping Centers has parent organization: University of Massachusetts Medical School Metabolic Disease Research Center Core Facility is organization facet of: University of Massachusetts Medical School Metabolic Disease Research Center Core Facility |
NIDDK UC2-DK093000 | Available to the research community | SCR_015369 | 2026-09-12 01:03:55 | 0 | |||||||||
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MMPC-University of California Davis Microbiome and Host Response Core Resource Report Resource Website 1+ mentions |
MMPC-University of California Davis Microbiome and Host Response Core (RRID:SCR_015361) | access service resource, core facility, resource, service resource | Core that offers measurement of gut permeability, plasma lipopolysaccharide binding protein (LBP) assay, and inflammatory profiling. | gut, microbiome, host response, digestion |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of California at Davis; California; USA has parent organization: National Mouse Metabolic Phenotyping Centers has parent organization: MMPC-University of California Davis is organization facet of: MMPC-University of California Davis |
NIDDK DK092993 | Available to the research community | SCR_015361 | 2026-09-12 01:03:55 | 9 | |||||||||
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University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Immunology Core Resource Report Resource Website |
University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Immunology Core (RRID:SCR_015409) | access service resource, core facility, resource, service resource | Core facility which provides a variety of assay services to evaluate cell-mediated and humoral responses to in animal models of gene therapies. | cell assay, assay service, gene therapy, animal model |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Pennsylvania Perelman School of Medicine; Pennsylvania; USA has parent organization: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis is organization facet of: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis |
Cystic Fibrosis | NIDDK P30DK047757 | Available to the research community | SCR_015409 | 2026-09-12 01:03:56 | 0 | ||||||||
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MMPC-University of Michigan Medical School Microvascular Complications Core Resource Report Resource Website |
MMPC-University of Michigan Medical School Microvascular Complications Core (RRID:SCR_015376) | access service resource, core facility, resource, service resource | Core which provides a complete range of microvascular phenotyping of murine models of diabetes, obesity and metabolic disease, including validated, reproducible and standardized phenotyping of the three major microvascular complications: diabetic polyneuropathy, nephropathy and retinopathy. | microvascular complications, dpn, dr, dn |
is listed by: NIDDK Information Network (dkNET) has parent organization: National Mouse Metabolic Phenotyping Centers has parent organization: University of Michigan; Ann Arbor; USA has parent organization: MMPC-University of Michigan Medical School is organization facet of: MMPC-University of Michigan Medical School |
NIDDK U2C-DK110768 | Available to the research community | SCR_015376 | 2026-09-12 01:03:55 | 0 | |||||||||
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MMPC-Vanderbilt University School of Medicine Metabolic Regulation Core Resource Report Resource Website |
MMPC-Vanderbilt University School of Medicine Metabolic Regulation Core (RRID:SCR_015377) | access service resource, core facility, resource, service resource | Core whose services include determining the components of energy balance with high precision and time resolution, providing robust imaging technology to monitor the dynamics of cellular process, and providing innovative mouse bariatric surgery models with application to basic and translational research. | pathophysiology, in vivo, metabolic core, metabolic imaging |
is listed by: NIDDK Information Network (dkNET) has parent organization: National Mouse Metabolic Phenotyping Centers has parent organization: MMPC-Vanderbilt University School of Medicine is organization facet of: MMPC-Vanderbilt University School of Medicine |
NIDDK U24 DK059637 | Available to the research community | SCR_015377 | 2026-09-12 01:03:55 | 0 |
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