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https://hillmanresearch.upmc.edu/research/shared-resources/cell-tissue-imaging
Core is part of the University of Pittsburgh Center for Biologic Imaging. Provides expertise in the design and implementation of experiments that use microscopy techniques and image analysis, including interpretation of morphological data. Services include to prepare, store and optimally analyze tissues and cells via morphological and mRNA and protein localization techniques; provide fixed cell and tissue imaging to Hillman investigators; provide live cell, live tissue, and live animal imaging to Hillman project leaders; perform detailed electron microscopy analysis of tissue structure; provide training related to use of and access to all instrumentation; Assist with experimental design and refinement, and evaluate experimental results including developing and implementing appropriate software algorithms to provide quantitative measurements.
Proper citation: University of Pittsburgh Hillman Cancer Center Cell and Tissue Imaging Facility CTIF Core Facility (RRID:SCR_028557) Copy
https://www.ucl.ac.uk/brain-sciences/ear/research-ear-institute/research-facilities/microscopy-unit
Core provides light and electron microscopy services.
Proper citation: University College London Ear Institute Microscopy Unit Core Facility (RRID:SCR_028564) Copy
https://igenseq.institutducerveau.org/
iGenSeq platform offers academic researchers and industry tools and services for genomic analysis: medium, high and very high throughput DNA and RNA sequencing, qPCR and ddPCR.
Proper citation: Paris Brain Institute iGenSeq Core Facility (RRID:SCR_028567) Copy
https://www.pm.mh.tum.de/en/path/comparative-experimental-pathology/
Core is fully equipped histological laboratory providing embedding station, automatic coverslipper, immunohistological platforms for standardized and automated immunohistochemistry, slide scanners, laser microdissection and light-sheet fluorescence microscope.
Proper citation: Technical University of Munich Institute of Pathology Comparative Experimental Pathology Core Facility (RRID:SCR_028771) Copy
https://www.cruk.cam.ac.uk/core-facilities/bioinformatics/
Core provides support for data analysis, statistics, and software development. Offers advice on experimental design, statistical modelling, and hypothesis testing and runs training courses to assist research scientists in performing their own analyses.
Proper citation: Cancer Research UK Cambridge Institute Bioinformatics Core Facility (RRID:SCR_028664) Copy
Core provides advanced instrumentation, consultation, and support for flow cytometry, light and electron microscopy, and small-animal imaging. Services include confocal microscopy, multi-plex whole slide imaging, conventional, widefield epifluorescence microscopy, Electron Microscopy, in vivo small animal PET, SPECT, CT, X-Ray, white light, fluorescence, and bioluminescence imaging, in vitro and in vivo X-Ray irradiation, multi-parameter flow cytometry, including conventional and spectral technologies, cell sorting, imaging cytometry, and advanced data analysis support.
Proper citation: Wayne State University Microscopy Imaging and Cytometry Resources MICR Core Facility (RRID:SCR_028700) Copy
Core specializes in multi-omics and next-generation sequencing data analysis from genetics, genomics, proteomics, metabolomics, and microbiome studies, with expertise in single-cell technologies as well as AI/ML applications in bioinformatics. Provides expertise, supports grant writing and manuscripts and comprehensive data analysis services.
Proper citation: Louisiana State University Pennington Biomedical Research Center Bioinformatics and Computational Biology Core Facility (RRID:SCR_028752) Copy
https://opioidcobre.org/cores/translational-and-transformative/
The BUH-COBRE Translational & Transformative Research Core is a shared research resource of the COBRE on Opioids and Overdose at Brown University Health. The Core supports the translation of research findings into clinical practice, community implementation, and public health impact. Services include qualitative research consultation, implementation and dissemination support, development of recruitment and educational materials, video production services, access to specialized research resources, and drug-checking research support.
Proper citation: Brown University BUH-COBRE Translational and Transformative Core Facility (RRID:SCR_028750) Copy
https://opioidcobre.org/cores/data-and-research-methods/
The BUH-OPIOID-COBRE DRM Core is a shared research resource of the COBRE on Opioids and Overdose at Brown University Health. The Data & Research Methods Core provides expertise in biostatistics, epidemiology, study design, data management, data visualization, and quantitative research methods. Services include statistical consultation, power and sample size estimation, analytic support, data infrastructure guidance, data collection strategies, and training for investigators conducting substance use, overdose, and related public health research.
Proper citation: Brown University BUH-OPIOID COBRE Data and Research Methods Core Facility (RRID:SCR_028751) Copy
Provides manufacturing micro- and nanofluidic devices for biomedical research, equipment and resources for applications with micro- and nanofabrication needs. Facility conisists of ISO class 7 cleanroom space, housing tools and materials for techniques including photolithography, nano-imprint lithography, plasma (dry) etching (ICP-RIE), wet etching, thin film deposition, scanning electron microscopy (VP-SEM), atomic force microscopy, contact angle goniometry, ellipsometry, profilometry, wafer dicing, wire bonding, laser ablation and engraving, 3D printing, hot embossing, and COMSOL software for device modeling. In addition, the facility has numerous microscopes for general inspection, ovens and furnaces, ultrapure water, and dedicated process fume hoods.
Proper citation: University of Kansas Nanofabrication Core Facility (RRID:SCR_028756) Copy
https://www.cruk.cam.ac.uk/core-facilities/genomics/
Core provides sequencing using Illumina next-generation sequencing and ONT long read technologies. Offers library preparation services for genomes, exomes, transcriptomes, and ChIP-seq experiments, expertise on the best approach for samples, depending on the quality of nucleic acids, scope of project, and available budget.
Proper citation: Cancer Research UK Cambridge Institute Genomics Core Facility (RRID:SCR_028699) Copy
Core offers standard and specialised histology services including tissue processing (murine, human and Drosophila tissue), processing of cellular material (cells, crypt cultures, organoids and spheroids), microtomy, cryo-microtomy, haematoxylin and eosin and specialised tissue stains along with automated immunohistochemical/ immunofluorescence/ in situ hybridisation analysis for specific labelling of individual tissue constituents.
Proper citation: Cancer Research UK Scotland Institute Histology Service Core Facility (RRID:SCR_028690) Copy
https://icemhh.pbrc.hawaii.edu/mgal/
Centralized molecular and analytical core that provides full service genomic library preparation, high-throughput DNA/RNA extractions, small molecule analysis, and routine isolation and storage of microbial strains. Specializes in environmental samples and offer low-cost fees for training and walk-in instrument use. Functions as a bio-repository of experimental arthropod models including Drosophila and other endemic insects.
Proper citation: University of Hawaii at Manoa Microbial Genomic and Arthropod Laboratory Core Facility (RRID:SCR_028713) Copy
https://www.ohsu.edu/flow-cytometry-core/monoclonal-antibodies
Core facility provides services including generation of new monoclonal antibodies , scaleup production , purification of antibody from existing cell lines and antibody conjugation.
Proper citation: OHSU Monoclonal Antibody Shared Resource Core Facility (RRID:SCR_028711) Copy
https://www.cruk.cam.ac.uk/core-facilities/bioanalytical-mass-spectrometry/
Core provides bioanalytical and pharmacokinetic support for the research groups and associated clinical trials within the institute, creating a bridge between the laboratory and clinic. Offers services performing bioanalysis using mass spectrometry, quantify therapeutic drugs as well as small molecule cancer related metabolites (targeted metabolomics), analysis of samples from matrices including plasma, blood, tissues, tumours, and cells.
Proper citation: Cancer Research UK Cambridge Institute Bioanalytical Mass Spectrometry Core Facility (RRID:SCR_028670) Copy
https://www.nottingham.ac.uk/deepseq/
Facility offers sequencing services including expertise, sequencing experiment design, data analysis. Provided instruments include Illumina MiSeq and NextSeq500 sequencing platforms for low and medium throughput, which can supply single or paired reads from 75 to 600 cycles, Oxford NanoPore Technologies GridION and PromethION platforms and MinIONs. Core helped to develop software tools for MinION data analysis.
Proper citation: University of Nottingham Deep Seq Core Facility (RRID:SCR_028703) Copy
https://icemhh.pbrc.hawaii.edu/mgal/
Molecular and analytical core that provides full service genomic library preparation, high-throughput DNA/RNA extractions and small molecule analysis, and serves as a bio-repository of microbes and experimental arthropod models.
Proper citation: University of Hawaii at Manoa Microbial, Genomic, and Arthropod Laboratory Core Facility (RRID:SCR_028689) Copy
https://health.usf.edu/publichealth/research/gac
Core provides analytic expertise and infrastructure needed to transform complex spatial data into actionable insights to support cancer research, precision population health, learning health system interventions and policy and resource planning at institutional and regional levels.
Proper citation: University of South Florida USFHealth Tampa General Hospital Cancer Institute Geospatial Analytics Core Facility (RRID:SCR_028682) Copy
https://aimrc.uark.edu/data-science-core/
Core specializes in artificial intelligence-based approaches to elucidate relationships between large imaging, bioenergetics, genomic, and proteomic data sets. Provided services include: 1) foundational training for those getting started with high-performance computing and Arkansas Research Platform (ARP), 2) training and support for the collaborative use of a 508 TB data storage server exclusively maintained for and catering to AIMRC researchers, 3) training for Python programming, basic data mining, and machine learning, 4) training and support for using open-source deep learning based biomedical imaging resources (e.g., ZeroCostDL4Mic and Bioimage Model Zoo), and 5) customized solutions for deep learning based and large foundational models based biomedical imaging analysis, multi-omics data integration and analysis, and quantitative analysis pipelines for large data sets.
Proper citation: University of Arkansas AIMRC Data Science Core Facility (RRID:SCR_028681) Copy
https://www.ous-research.no/flow/
Core provides services, including sample analysis and cell sorting, as well as instrumentation, software, and technical expertise/advice for a variety of flow cytometric protocols. Training is available to enable users to run the cytometers themselves.
Proper citation: Oslo University Hospital Flow Cytometry Core Facility (RRID:SCR_028716) Copy
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