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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://chicagodiabetesresearch.org/cores/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 30,2023. Core facility that provides support to investigators in designing and carrying out translational studies assessing outcomes for patients with diabetes, or populations at risk.
Proper citation: Chicago Center for Diabetes Translation Research Outcomes Improvement Core (RRID:SCR_015221) Copy
Core whose services include designing, constructing and validating custom plasmids and other DNA vectors, making custom genome engineering reagents, including TALENs, transposons, bacterial artificial chromosomes and CRISPRs, and providing consults and training on a variety of topics, including rodent and zebrafish transgenic and knockout model development support.
Proper citation: Mayo Clinic Center for Cell Signaling in Gastroenterology Gene Editing and Cell Engineering Core (RRID:SCR_015226) Copy
https://keck.usc.edu/liver-diseases-research-center/about-the-center/scientific-cores/
Core that provides instrumentation (confocal and fluorescence microscopy) and technical support for cell biology and pathophysiology studies.
Proper citation: USC Liver Transplant Program and Center for Liver Disease Cell and Tissue Imaging Core (RRID:SCR_015234) Copy
Administrative core for the Michigan Center for Diabetes Translational Research. It works to raise awareness of and interest in type 2 diabetes research, manage its grant program, and support investigators working on both clinical and implementationl diabetes research.
Proper citation: Michigan Center for Diabetes Translational Research Administrative Core Facility (RRID:SCR_015194) Copy
http://www.baltimorepkdcenter.org/antibody/index.shtml
Core which supports the work of the Baltimore Polycystic Kidney Disease research center by providing antibody validation services and vectors to researchers.
Proper citation: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Antibody Validation and Vector Core (RRID:SCR_015318) Copy
http://www.uab.edu/medicine/hrfdcc/cores/c
Core whose goals include to characterize mouse models of HRFD in vivo, establish mTERT and hTERT immortalized cell lines, and the physiological and molecular characterization of HFRD cell lines.
Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Cellular Physiology Resource (RRID:SCR_015316) Copy
http://medicine.yale.edu/labmed/ycceh/cores/core_a/index.aspx
Core facility which provides emerging technologies in hematology and relevant training for junior investigators. Its services include in vitro hematopoiesis assays services, automated complete blood counts, morpholoigcal analyses, CRISPR based genomic editing, and FACsorting and analysis.
Proper citation: Yale Cooperative Center of Excellence in Hematology Cell Preparation and Analysis Core (RRID:SCR_015317) Copy
https://www.cincinnatichildrens.org/research/divisions/d/dhc/cores/clinical
Core that is meant to provide members with biostatistical support and the infrastructure to execute disease-based clinical research. Its services include advising on research designs, including project implementation and data collection methods, guidance on appropriate statistical methods based on study design, training and access to REDCap (Research Electronic Data Capture) for research studies, and reviewing REDCap Data Base Structure.
Proper citation: Cincinnati Digestive Health Center Clinical Component-Data Analysis and Management (RRID:SCR_015200) Copy
http://www.massgeneral.org/csibd/cores/molbiology.aspx
Core that provides services in the utilization of advanced genetics and molecular biological techniques and facilitates the implementation of advances in genomics and molecular biology to IBD research. It provides access to capital or resource-intensive methodologies, such as laboratory automation cDNA and siRNA libraries, and BAC-centered recombinant DNA techniques.
Proper citation: Center for the Study of Inflammatory Bowel Disease Genetics Genomics and Molecular Biology Core (RRID:SCR_015201) Copy
http://www.baltimorepkdcenter.org/cell/index.shtml
Core faiclity that provides researchers with cell culturing and engineering services.
Proper citation: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Cell Culture and Engineering (RRID:SCR_015323) Copy
https://www.uab.edu/medicine/obriencenter/cores/bioanalytical-core
Core that provides bioenergetics, oxidative stress analysis and metabolite analysis support for AKI research. It includes protocols and technology for bioanalytical analysis of oxidative stress and cellular bioenergetics as well as post-translational modifications.
Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research Bioanalytical Core (RRID:SCR_015280) Copy
http://sharedresources.fredhutch.org/core-facilities/experimental-histopathology
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 27,2022. Core facility which provides various histology, histochemistry, immunochemistry, and pathology services. They also provide technical training for histopathological methods and tools.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Experimental Histopathology Shared Resource (RRID:SCR_015329) Copy
Core provides essential optical technologies and applications expertise to support faculty research by providing microscopic technology to all faculty members that facilitates their study of GI cellular signaling cascades, educating and training faculty members in the use of both basic and sophisticated cellular imaging methods, and developing and applying optical imaging technologies to GI tissues and cells based on faculty needs.
Proper citation: Mayo Clinic Center for Cell Signaling in Gastroenterology Optical Microscopy Core (RRID:SCR_015211) Copy
http://www.cure.med.ucla.edu/cores/molecular-vector-peptidomics
Core whose aim is to promote and facilitate basic and translational GI research. Its services include consultation and troubleshooting in techniques for efficient gene delivery, as well as cloning and functional protein expression in mammalian cells in vitro and in vivo and consultation and to perform customized gene expression profiling, cytological phenotype profiling, and high-throughput molecular screening studies by utilizing high-throughput and highly automated robotic systems.
Proper citation: CURE - Digestive Diseases Research Center Molecular Biology and Peptidomics Core (RRID:SCR_015213) Copy
http://www.baltimorepkdcenter.org/clinical/index.shtml
Core facility that provides clinical applications and methods to make kidney research translational and applicable to care settings.
Proper citation: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Clinical and Translational Core Resource (RRID:SCR_015291) Copy
http://www.dukekidneycenter.org/cores/animal-models-core
Core facility that provides access to a range of experimental models of kidney, heart and vascular diseases. It also provides comprehensive phenotyping services for kidney functions, blood pressure and other cardiovascular functions.
Proper citation: Duke O'Brien Center for Kidney Research Animal Models Core (RRID:SCR_015267) Copy
https://www.cincinnatichildrens.org/research/divisions/n/nephrology/center-of-excellence/cores
Core aims include to empower the Nephrology Center of Excellence investigators by providing access to integrated state of the art gene expression technologies with which to apply genomics methods to accelerate molecular nephrology research, educate, assist, and improve the use of global genomics approaches, infrastructure and specialized tools for the enhancement of research productivity and discovery by the Nephrology Center of Excellence investigators, and develop and disseminate specialized data sets and the use of advanced analytic techniques and/or protocols to facilitate translation of research data to accelerate basic and applied research and its translation to improved clinical care.
Proper citation: Pediatric Centers of Excellence in Nephrology at Cincinnati Children's Hospital Medical Center Gene Expression Core (RRID:SCR_015301) Copy
http://www.mayo.edu/research/centers-programs/molecular-genetics-proteomics-core/overview
Core services include mutation screening of cell lines derived from ADPKD patients, mutation screening of large, typical ADPKD populations, genetic screening of atypical PKD families, cystic Kidney and Liver Disease Biobank (CKLBB) from ADPKD patients, and urine collection and fractionation.
Proper citation: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Molecular Genetics and Biomarker Core (RRID:SCR_015308) Copy
https://www.cincinnatichildrens.org/research/divisions/n/nephrology/center-of-excellence/cores
Core that provides quantitation and identification of protein changes by 2D gel-based methods and isotope tagging and nanoLC-MS/MS, identification of protein biomarkers detected from biofluids in the Biomarker Core, and provision of dedicated and expert Biostatistical and Bioinformatic support for data analysis.
Proper citation: Cincinnati Children's Hospital Pediatric Center of Excellence (RRID:SCR_015306) Copy
https://www.uab.edu/medicine/obriencenter/cores/pre-clinical-studies-of-aki
Core that provides services such as expertise in development and training in the use of rodent models of AKI, specifically in the setting of ischemia/reperfusion (I/R) injury, sepsis and renal transplantation, gamma-ray imaging (gamma camera, microSPECT/CT, microPET/CT), metabolic assessments of kidney O2 consumption, and technical expertise in isolation of primary renal and vascular cell in culture.
Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research Pre-Clinical Studies of AKI (RRID:SCR_015278) Copy
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