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https://www.ohsu.edu/dna-services-core

Services offered include Human cell line authentication: Accurate validation of human cell lines using STR analysis and meeting the ANSI/ATCC requirements; Fragment analysis: Detection of changes in length of specific DNA sequence to indicate presence or absence of genetic marker; Oligo synthesis: Creation of custom primers and probes for oligo and siRNA synthesis through Integrated DNA Technologies (IDT); DNA quantification: Quantification, size and quality assessment of DNA samples; Consulting: For project design and sample preparation assistance.

Proper citation: OHSU DNA Services Core Facility (RRID:SCR_009968) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/scxc/

Offers in vivo services specializing in immunodeficient and xenograft models (PDX, humanized immune system). Facility has dedicated BSL2 barrier space equipped with optical imaging, for applications ranging from immunotherapy, cancer biology, infectious diseases and regenerative medicine. Offers services centered around repository of live and fully annotated cells from adult patients with hematologic malignancies (AML, ALL, MPN, MDS), and hematopoietic stem/progenitor cells from healthy donors (BM, CB, and FL).

Proper citation: Pennsylvania University Perelman School of Medicine Stem Cell and Xenograft Core Facility (RRID:SCR_010035) Copy   

•   Source: SciCrunch Registry

https://nyumc.ilab.agilent.com/service_center/4273

Core offers services for researchers who want to apply advanced molecular genetic techniques in rodent models of physiology and disease. Provides expertise in generating novel mutant and transgenic mouse strains using genome engineering in mouse embryos and in embryonic stem cells (ESCs). Available technologies include:Generation of genome-edited mice by embryo pronuclear microinjection of DNA and genome editors (e.g., CRISPR/Cas9, site-specific recombinases) or traditional BAC transgenesis;Generation of genome-edited mice from mouse embryonic stem cells (mESCs) by chimeric blastocyst injection;Generation of genome-edited mice from mESCs by tetraploid blastocyst injection; Generation of mice from induced pluripotent stem cells;Assisted reproductive technologies; Sperm and embryo cryopreservation, storage and import/export;in vitro fertilization (IVF); Embryo rederivation technologies for animal import into barrier vivaria through quarantine.

Proper citation: NYU Langone’s Advanced Rodent Transgenics Laboratory ART-Lab Core Facility (RRID:SCR_017692) Copy   

•   Source: SciCrunch Registry

https://www.thermofisher.com/order/catalog/product/4406016#/4406016

Applied Biosystems 3500xL 24-capillary Genetic Analyzer is used for the Human Identification application.Genetic analyzer that utilizes capillary electrophoresis for genetic analysis. It has capillary lengths of 50 cm or 36 cm and can use 384 well plates or 96 well plates.

Proper citation: Thermo Fisher: Applied Biosystems: 3500xl Genetic Analyzer (RRID:SCR_018438) Copy   

•   Source: SciCrunch Registry

https://cancer.dartmouth.edu/scientists-researchers/clinical-pharmacology

Supports Dartmouth Cancer Center investigators in design, performance, data analysis, and interpretation of pharmacology objectives in preclinical, clinical and epidemiological studies.

Proper citation: Dartmouth College Clinical Pharmacology Shared Resource Core Facility (RRID:SCR_000873) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/facility/ems/

Core provides access to instruments including:FEI Tecnai 12 Spirit TEM, FEI Tecnai F20 (200kV) FEG-TEM 200kV FEG-TEM,Gatan US4000 4k x 4k CCD, bottom-mount,CryoTEM and electron tomography,High-resolution TEM;FEI Tecnai F20 (200kV) FEG-TEM,300kV FEG-TEM,Gatan US4000 4k x 4k CCD, bottom-mount,CryoTEM and electron tomography,High-resolution TEM,FEI/Phillips CM100 (100kV) TEM,100kV, tungsten TEM,2k x 2k AMT CCD, bottom-mount.

Proper citation: Colorado University at Boulder EM Services Core Facility (RRID:SCR_001432) Copy   

•   Source: SciCrunch Registry

https://genome.med.harvard.edu/

Provided core services include Sanger DNA Sequencing, Next Generation DNA Sequencing (Four Illumina MiSeqs, four Illumina NextSeq 500s and one Illumina NovaSeq 6000),Next Generation Automated Library Sample Prep (Perkin Elmer Sciclone Genomic, ChIP, RNAseq and other methods), Single Cell DNA and RNA-Seq (10X Genomics Chromium), Bioanalyzer Analysis DNA and RNA (Two Agilent 2100 BioAnalyzers and two Agilent 2200 TapeStations), Qiagen Qiacube Automated DNA / RNA Prep (single to multiple samples), Oligonucleotide Ordering (IDT Portal), Reagents and Supplies Ordering (multiple vendors / products). Facility web based Laboratory Information Management System provides users with access to order services and supplies as well as retrieve data and review and pay invoices all online.

Proper citation: Harvard Medical School Biopolymers Core Facility (RRID:SCR_007175) Copy   

•   Source: SciCrunch Registry

https://www.urmc.rochester.edu/research/rochester-genomics-center.aspx

Provides core laboratory support, technical consultation, assistance with experimental design and data analysis for investigators using high throughput genomic sequencing, genotyping and gene expression in their research programs.Provides support for RNA-Seq, ATAC-seq, ChIP-Seq, Single Cell RNA-seq, Spatial Transcriptomics, Exome/Genome sequencing, Whole Genome and Reduced Representation Bisulfite Sequencing (WGBS, RRBS), 16S rRNA Sequencing, Small RNA-Seq, Metatranscriptomics, qRT-PCR, processing of RNA/DNA, as well as custom applications and approaches. Bioinformatic analysis support is also available.

Proper citation: University of Rochester Genomics Research Center Core Facility (RRID:SCR_012359) Copy   

•   Source: SciCrunch Registry

http://www.montana.edu/massspec/index.html

Provides access to mass spectrometers and mass spectrometry expertise. The facility currently maintains the following equipment Waters Synapt-XS Q-IMS-TOF with Waters I-Class UHPLC; Agilent 6538 Q-TOF with Agilent 1290 UHPLC;Agilent 7800 Inductively Coupled Plasma with Laser Ablation (193 nm);Bruker micrOTOF with Agilent 1290 UHPLC; Agilent 6490 Triple Quadrupole Mass Spectrometer; Bruker MALDI Autoflex; Agilent GC-MS; Waters Synapt G2S-i Q-TOF with Ion Mobility.

Proper citation: Montana State University Mass Spectrometry Core Facility (RRID:SCR_012482) Copy   

•   Source: SciCrunch Registry

https://www.urmc.rochester.edu/research/flow-core.aspx

Provides investigators with instrumentation along with expertise. Core instrumentation includes traditional analytical cytometers, full spectrum cytometer, cell sorters, imaging cytometers, small(nano) particle detection system, metabolomics instrument, and mass cytometer.

Proper citation: University of Rochester Medical Center Flow Cytometry Core Facility (RRID:SCR_012360) Copy   

•   Source: SciCrunch Registry

https://www.urmc.rochester.edu/research/electron-microscope.aspx

Electron Microscopy Resource supports ultra-structural interrogation of tissues, biologic solutions and nanomaterials for investigators utilizing transmission electron microscopy (TEM), scanning electron microscopy (SEM) and cryo-TEM.

Proper citation: University of Rochester Medical Center Electron Microscopy Core Facility (RRID:SCR_012366) Copy   

•   Source: SciCrunch Registry

https://azgc.arizona.edu

Core provides molecular biotechnology services and current molecular genetic methods. Services include DNA and RNA Extraction, transgenic mouse genotyping, Human Cell line Authentication, Sanger DNA Sequencing, Next-Generation sequencing platforms, Microsatellite DNA Typing, Agena multiplex SNP Genotyping, Real-time PCR, NanoString Gene Expression Analysis. Specializes in custom workflows that couple services with specific research needs.

Proper citation: Arizona Genetics Core (RRID:SCR_012429) Copy   

•   Source: SciCrunch Registry

http://www.ohri.ca/stemcore/Default.aspx

StemCore Laboratories is a high-throughput genomics facility within the Ottawa Hospital Research Institute (OHRI). Core is capable of facilitating large-scale scientific research and biotechnology projects.Provides infrastructure for genomics, bioinformatics, and proteomics.

Proper citation: Ottawa Hospital Research Institute StemCore Laboratories Core Facility (RRID:SCR_012601) Copy   

•   Source: SciCrunch Registry

https://www.salk.edu/science/core-facilities/integrative-genomics-and-bioinformatics-core/

Core houses state-of-the-art equipment in sequencing and genomics, including high-throughput sequencing systems such as Illumina NovaSeq 6000, NextSeq 2000, MiniSeq, and PacBio Sequel IIe system (long-read sequencing), as well as 10x Genomics Chromium Controller single-cell solution, NanoString nCounter MAX Analyzer, and GeoMx Digital Spatial Profiler instrument, along with QuantStudio Real-Time PCR instruments.

Proper citation: Salk Institute Next Generation Sequencing Core (NGS) (RRID:SCR_014846) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/histopathology-core

Provides routine and customized histology and immunohistochemistry services critical for progress of biomedical research.

Proper citation: OHSU Histopathology Shared Resource Core Facility (RRID:SCR_009977) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/gene-profiling-shared-resource

Full service genomics facility providing research scientists and clinicians with services for RNA expression profiling, DNA variation analysis, and nucleic acid extraction.

Proper citation: OHSU Gene Profiling Shared Resource Core Facility (RRID:SCR_009975) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/multiscale-microscopy-core

Multiscale Microscopy Core at OHSU is electron microscopy core that provides services and training to academic and corporate users.

Proper citation: Oregon Health and Science University Multiscale Microscopy Core Facility (RRID:SCR_009969) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/advanced-light-microscopy-core

Provides confocal image analysis and presentation training, microscope training, microscope access service, deconvolution training, super resolution imaging and training service. Offers research scientists access to high-end instrumentation for fluorescence microscopy. Offers support with image acquisition, processing, analysis and presentation.

Proper citation: OHSU Advanced Light Microscopy Core Facility (RRID:SCR_009961) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/xd/research/research-cores/advanced-computing-center/index.cfm

Provides technology solutions to meet non enterprise IT needs across OHSU for healthcare including limited clinical research project support, academic, and research missions. ACC is also home to Exacloud HPC cluster.

Proper citation: OHSU Advanced Computing Center Core Facility (RRID:SCR_009959) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/research-cores/massively-parallel-sequencing-shared-resource-mpssr

As of January 1, 2024, the Integrated Genomics Laboratory is one shared resource comprising the former Massively Parallel Sequencing Shared Resource, the Gene Profiling Shared Resource, and the DNA Services Core. Please be aware that the reorganization is an ongoing process, particularly regarding our iLab integration.Provides RNA-sequencing for gene expression analysis, DNA resequencing for single nucleotide polymorphism discovery, DNA resequencing for copy number variation discovery, ChiP-sequencing for promoter analysis, DNA methylation analysis, De novo sequencing for unique genomes, Sequence capture service. Offers sequencing including genome resequencing, transcriptome analysis, miRNA analysis, and prometer analysis via ChIP-seq.

Proper citation: OHSU Massively Parallel Sequencing Shared Resource Core Facility (RRID:SCR_009984) Copy   

•   Source: SciCrunch Registry