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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.uab.edu/medicine/obriencenter/cores/pre-clinical-studies-of-aki
Core that provides services such as expertise in development and training in the use of rodent models of AKI, specifically in the setting of ischemia/reperfusion (I/R) injury, sepsis and renal transplantation, gamma-ray imaging (gamma camera, microSPECT/CT, microPET/CT), metabolic assessments of kidney O2 consumption, and technical expertise in isolation of primary renal and vascular cell in culture.
Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research Pre-Clinical Studies of AKI (RRID:SCR_015278) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/michael-hooker-microscopy-core
Core that provides advanced digital light microscopy, image processing and analysis resources for users from the UNC Chapel Hill campus. It also offers instrumentation and instruction to enable users to acquire, process and analyze images from a wide variety of sample types.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Michael Hooker Microscopy Core Facility (RRID:SCR_015390) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/ClinicalTranslationalCore
Core whose services include biospecimen collection and storage, development of lung imaging outcomes, imaging training, and biostatical analysis.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Clinical Translational Core (RRID:SCR_015391) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/TissueProcurmentandCellCultureCore
Core that provides standardized cell cultures for cystic fibrosis research, notably normal, cystic fibrosis and disease control cells, tissues and fluids. Its functions include tissue procurement, airway epithelial cell isolation and culture, collecting airway surface liquid from in vivo and in vitro samples, genetic manipulation of cell cultures, creating and characterizing novel cell lines, and translation of technology and reagents to the greater cystic fibrosis research community.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Tissue Procurement and Cell Culture Core (RRID:SCR_015394) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/mucuscore
Core that provides a service to quantify the concentration of given mucus samples for both total mucus concentration and the absolute relative contributions of each secreted mucin. It also provides quantitation of extracellular DNA. The mucus biphysics subcore component, provides core users with information on the biophysical properties of the mucus layer and its interaction with the cell surface.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Mucus and Mucin Biochemistry and Biophysics Core (RRID:SCR_015393) Copy
http://depts.washington.edu/cfrtc/clinical/
Core that aims to provide preclinical support for novel therapeutics, work with other biomedical cores to enhance and support bacterial and human specimen repositories, and support developmental research and training.
Proper citation: Cystic Fibrosis Center - University of Washington Clinical Core (RRID:SCR_015402) Copy
http://www.medschool.umaryland.edu/norc/Cores/Molecular-Genetics--Nutrigenomics-MGN-Core/
Core that aims to discover genes and gene-nutrient interactions associated with risk of obesity, diabetes, hypertension, atherogenesis and longevity. Its goal is to understand the molecular, cellular and physiological roles of genes in the etiology of obesity, diabetes, and associated metabolic abnormalities.
Proper citation: Mid-Atlantic Nutrition Obesity Research Center Molecular Genetics and Nutrigenomics Core (RRID:SCR_015459) Copy
http://www.med.unc.edu/cgibd/cores/advanced-analytics
Core facility provides solutions for studying proteins, peptides, and other molecules, including mRNA and cDNA. The Core's immunotechnologies (IT) component provides consultation, ordering, and immunoassay services, and supports a variety of analytes in both traditional ELISA/EIA and xMAP-based multiplex bead assay formats.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Advanced Analytics Core (RRID:SCR_015613) Copy
http://sph.unc.edu/norc/nutrigenetics/
Core facility whose services include grant writing assistance and consultation, laboratory analyses, brokerage services, and analytical services.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Nutrigenetics Core (RRID:SCR_015464) Copy
http://sph.unc.edu/norc/metabolic/
Core whose goals are to encourage and facilitate the use of biomarkers for nutritional epidemiological and intervention studies. It provides access to techniques and equipment to bench scientists, as well as assays for investigators without lab facilities.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Metabolic Molecular Phenotyping Core (RRID:SCR_015463) Copy
http://mmoc.med.umich.edu/CoreHumanPhenotyping.php
Core that aims to enhance and expand the research capabilities of investigators performing clinical and translational studies related to nutritional interventions, obesity, or obesity-related disorders in humans. Its services include standardized nutritional assessments and physiological testing of human subjects, researcher assistance in conducting dietary, behavioral, and/or exercise intervention in human subjects, and training in techniques or the assistance in development of new techniques and technologies for the metabolic and neurobehavioral assessment of humans.
Proper citation: University of Michigan Nutrition and Obesity Research Center Human Phenotyping Core (RRID:SCR_015460) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/proteomicsCore.html
Core facility that uses mass spectrometry coupled to one (1D) and two (2D) dimensional separations by column chromatography or gel electrophoresis to identify, quantify or characterize proteins and their post-translational modifications, that are expressed in well characterized protein fractions from the small intestine, colon, kidney, liver and pancreas. Techniques such as difference gel electrophoresis (DIGE), isobaric tag for relative and absolute quantitation (iTRAQ), tandem mass tags (TMT) and stable isotope labeling of amino acids in cell culture (SILAC) as well as non-labeling methods (MudPIT, multi-dimensional protein identification technology) are available for quantifying relative differences in protein expression and post-translational modifications, such as acetylation, glycosylation, phosphorylation, nitrosation, ubiquitination and novel cleavage sites.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Proteomics Core (RRID:SCR_015597) Copy
http://www.norc.uab.edu/corefacilities/physicalactivity
Core that provides physical activity services and consultation for UAB investigators. Services include aerobic fitness tests, supervised resistance training, submaximal ease/economy locomotion tests, and strength and functional tests, with respective measurements taken.
Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Physical Activity Core (RRID:SCR_015474) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/imagingCore.html
Core facility that provides state-of-art light microscopy technology to the members of the Hopkins Basic Research Digestive Disease Development Center and to the whole Hopkins scientific community.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Image Core (RRID:SCR_015593) Copy
https://hddc.hms.harvard.edu/bio-repository-and-data-registry-human-material
Core facility that supports basic, translational, and clinical research in the digestive diseases by providing access to human materials and resources in statistics and study design. It also aims to to forge connections and support collaboration between HDDC Clinical Associates and Members, support a well-organized infrastructure for acquisition and storage of clinical samples, and provide professional support in biostatistics and study design to HDDC members and Clinical Associates.
Proper citation: Harvard Digestive Diseases Center Bio-Repository and Data Registry for Human Material (RRID:SCR_015590) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/integratedPhysiology.html
Core facility that provides Center investigators and their laboratories the tools and advice needed to establish and study mouse (including transgenic and knockout) and human (i.e. GI organoids) physiology of GI disease.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Integrated Physiology Core (RRID:SCR_015591) Copy
http://norc.pbrc.edu/animal_core.asp
Core that is comprised of the Animal Models Subcore and Animal Phenotyping Subcore. The former provides expertise and services for design and construction of transgenes, ES cell transfection and screening, pronuclear injection, and cryopreservation. The latter provides expertise and services for metabolism, physical activity, body composition, and behavioral research.
Proper citation: Pennington Biomedical Research Center Nutrition and Obesity Research Center Animal Models and Phenotyping Core (RRID:SCR_015443) Copy
http://norc.pbrc.edu/human_core.asp
Core that provides users with expertise and phenotyping services for different stages in life. It specifically provides services for obesity research, unique populations (pregnant women, children, infants, etc.), and clinical and translational studies through their Energy Balance subcore and Behavioral subcore.
Proper citation: Pennington Biomedical Research Center Nutrition and Obesity Research Center Human Phenotyping Core (RRID:SCR_015440) Copy
http://norc.pbrc.edu/molecular_core.asp
Core that includes a genomics subcore that provides services in genomics such as Sanger DNA sequencing and fragment analysis service, microarray analysis service, quantitative PCR, robotic pipetting for quantitative PCR and custom pipetting projects, and software analysis solutions. The Cell Biology &and Bioimaging subcore provides histology and specipmen preparation, imaging, and flow cytometry/cell sorting.
Proper citation: Pennington Biomedical Research Center Nutrition and Obesity Research Center Molecular Mechanisms Core (RRID:SCR_015441) Copy
http://sph.unc.edu/norc/clinical-program/
Core for nutrition researchers that consists of two subcores: the Human Research Core and the Nutrition Research Kitchen and Metabolism Core. The Human Research Core provides human metabolism and body composition assessments, clinical laboratory and support services, and preparation and delivery of precisely designed meals for study participants. The Nutrition Research Kitchen and Metabolism Core offers nutrition research assistance to complement clinical studies.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Clinical Nutrition Research Facilitation Program (RRID:SCR_015444) Copy
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